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Building Healthy Lifestyles

Chronic Respiratory
Asthma
Clinical Guide

Building
Healthy 388-6654
1-866-506-6654 Lifestyles
Asthma

We would like to acknowledge the contribution of the following groups:


Chronic Respiratory Interdisciplinary Working Group

Chronic Disease Physician Advisory Group

Chronic Disease Clinical Leadership Group

Specialist Consultants

Chronic Respiratory Clinical Champions

CHR Asthma Program Committee

Utilizing the Chronic Care model, these groups developed the Asthma Clinical Guide as a decision-
support tool for improved functional and clinical outcomes. This Guide supports primary care
interdisciplinary team-based practice with a strong focus on self-management.

Please use and reproduce with acknowledgement to the Chinook Health Region.

Chronic Disease Management and Prevention Network:


An Alberta Health Capacity Building Initiative

Chinook Health Region


Lethbridge, Alberta
April 2006

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Asthma

Table of Contents

1. Diagnosis
a. Definition ............................................................................................................5
b. Risk Factors .........................................................................................................5
c. Screening .............................................................................................................6
d. Signs and Symptoms............................................................................................6
e. Testing and Evaluation ........................................................................................6
f. Further Testing ....................................................................................................7
g. Algorithm ............................................................................................................8

2. Classification/Type/Staging
a. Stages/Types of Disease ........................................................................................11

3. Patient Care Flow Sheet for Health Teams


a. Patient Care Flow Sheet ......................................................................................13
b. Key Clinical Summary .........................................................................................14

4. Management Strategies for Health Teams


a. Goals of Management ..........................................................................................15
b. Key Clinical Targets .............................................................................................15
c. Non-Pharmacologic Strategies .............................................................................15
d. Pharmacologic Strategies......................................................................................16

5. Management Strategies for Patients/Clients


a. Self-Care Support Information/Handouts/Tools .................................................21
b. Patient/Client Checklist for Evidence-Based Care ................................................25

6. Referral to Specialists/Specialty Program


a. Indications for Referral to Medical Specialists ......................................................27
b. Indications for Referral to Specialty Programs ......................................................27
c. Local Contacts .....................................................................................................27

7. References
a. Evidence ..............................................................................................................29
b. On-line Resources ...............................................................................................29
c. Supplementary Handouts Available .....................................................................29

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Asthma

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1. Diagnosis Asthma

BUILDING HEALTHY LIFESTYLES


CHRONIC RESPIRATORY-ASTHMA
Unless clinical practice guidelines are followed, the danger of both Reactive Airways Disease (RADS) is poorly defined, confusing and
under- and over-diagnosis exists. The interpretation and availability should not be used in lieu of “possible or probable Asthma”.
of tests to assess variable airway obstruction is inconsistent. Because
of the variable nature of the disease over time, the tests for airway b. Risk Factors
obstruction and hyper-responsiveness may not reveal a problem even
when asthma exists. Major risk factors:
i. Personal history of atopy, especially atopic dermatitis
ii. Parental history of asthma or eczema
1. Diagnosis iii. Three or more episodes of wheeze during the first three years
a. Definitions: of life

Asthma: is characterized by paroxysmal or persistent symptoms Minor risk factors:


such as dyspnea, wheezing, chest tightness, sputum production and i. Eosinophilia
cough associated with variable airflow limitation and airway hyper- ii. Wheezing without colds
responsiveness to endogenous or exogenous stimuli. iii. Allergic rhinitis
iv. Environmental tobacco smoke (ETS)
Exercise Induced Bronchospasm (EIB): is a reversible airway
obstruction that occurs during or after strenuous physical exertion. OCCUPATIONAL ASTHMA (OA)
Solitary EIB is not asthma and it is important to distinguish if exercise
induced symptoms are the result of poorly controlled asthma. Highest risk occupations and asthma-producing substances

EIB versus Asthma OCCUPATION ASTHMA-PRODUCING


SUBSTANCES
A therapeutic trial is a practical way to confirm EIB. The client Adhesive handlers Chemicals such as acrylate
takes B-2 agonists, 15 minutes prior to exercise; the EIB diagnosis is
confirmed if the medications prevent or diminish symptoms. The Animal handlers, vets, researcher Animal proteins
challenge is to distinguish whether or not the patient has asthma Bakers, Millers Cereal Grains
with an exercise exacerbation or has solitary EIB. Because treatment Carpet makers Gums
is different for these two conditions, it is important to evaluate
the patient for asthma using patient history, physical exam and Electronic workers Soldering resin
pulmonary function tests (spirometry). Forest workers, Carpenters, Wood dust
Cabinet makers
Occupational Asthma (OA) – is asthma induced by exposure to a
specific agent in the workplace; is the most common occupational Hairdressers Chemicals such as persulfate
lung disease in developed countries. OA has been estimated to cause Healthcare professionals Latex and chemicals such as
5 – 15 % of adult onset asthma. glutaraldehyde
• An occupational cause should be suspected for all new cases of Janitors, Cleaning staff Chemicals such as chloramine-T
asthma in adults Pharmaceutical workers Drugs, enzymes
• Temporal associations are not sufficient to diagnose work-related Seafood processors Seafood
asthma and objective tests are required to confirm the diagnosis.
Workers with asthma symptoms should not be told to leave their Shellac handlers Chemicals such as amines
job until diagnosis is proven because part of the diagnostic work- Solderers, Refiners Metals
up of OA may involve a return trial to work. Spray painters, Insulation Chemicals such as diisocyanates
• Referral to a medical specialist for evaluation of OA installers, Plastic & Foam
industry workers
Irritant-induced Asthma – is caused by single or multiple exposures
to high concentrations of an irritant vapour, fume or smoke in people Textile workers Dyes
who have no previous diagnosis or history of asthma symptoms. The Users of plastics, epoxy resins Chemicals such as anhydrides
term “Reactive airways dysfunction syndrome” or RADS is used
when the condition is caused by a single exposure.

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1. Diagnosis Asthma

c. Screening Findings with asthma that may be present are:


• use of accessory muscles of respiration
There is currently no organized approach to screening for asthma in • tracheal tug
Canada. • indrawing
• hyperinflation of the chest
d. Signs and Symptoms • decreased air entry
• prolonged expiration
Asthma
• wheezing
• Coughing • wheeze with forced expiration
• Wheezing • silent chest

• Chest tightness • Lung function tests (2 types): Objective measurements are


needed to confirm the diagnosis of asthma and to assess its
• Shortness of breath severity accurately in all symptomatic patients.
• Trouble sleeping because of breathing difficulty
i. Spirometry (preferred method)
• Reduced physical activity due to breathing difficulty - A 12% (at least 180 mL in adults) or greater improvement in
Forced Expiratory Volume (FEV)1.0 15 minutes (10 minutes
EIB:
is more practical and used in the LRH PFT lab) after use of
• Coughing, wheezing, shortness of breath and chest tightness an inhaled short-acting beta-2 agonist will confirm diagnosis
immediately following 6 to 8 minutes of strenuous exercise. of asthma*
These symptoms may occur during or after exercise. - A 20% (at least 250mL in adults) or greater improvement in
FEV1.0 after 10-14 days of inhaled glucocorticosteriods or
e. Testing and Evaluation ingested prednisone, when symptoms are stable will confirm
diagnosis of asthma
Evaluation and diagnosis of asthma in clients able to perform
- A 20% (at least 250 mL in adults) or greater spontaneous
lung function tests (Usually 6 years of age and older):
variability in FEV1.0 over time is considered significant and
There is no one definitive test that can be used to diagnose asthma, will confirm the diagnosis of asthma
requiring the bringing together of many sources of information in
ii. Peak Expiratory Flow or PEF (used when spirometry is
order to reach such a diagnosis. At the present time, diagnosing
unavailable or home monitoring is required to diagnose)
asthma is based on the following:
- Variable airflow obstruction can be documented by home
• the presence of typical symptoms of asthma and an improvement measured PEF that shows a 20% or greater diurnal variability
in these symptoms with asthma medication over a period of several weeks. This can confirm the
• evidence of variable airflow limitation and/or obstruction diagnosis of asthma.
- A 20% or greater improvement in PEF, 15 minutes (10
• in some circumstances, evidence of hyper-responsiveness of the minutes is more practical) after the administration of a short
airways using a provocation challenge test acting beta-2 agonist may be used to confirm asthma in a
Steps in primary care setting to accurately diagnosis asthma, suspect physician’s office when spirometry is not available.
asthma based on symptoms, physical exam and patient history. - Both these methods are not as reliable as spirometry.
Next, confirm diagnosis through lung function tests showing • Therapeutic trial of asthma medications, which should include
variable airflow obstruction and/or response to trial of asthma Inhaled Corticosteroids (ICSs) daily and short-acting B-2 agonist
medications. as needed for a period of 2-4 weeks may be helpful in confirming
• Thorough history: covering symptoms and pattern of symptoms the diagnosis of asthma.
as well as what triggers the symptoms. Personal history of atopy Evaluation and diagnosis of asthma in clients unable to perform
(eczema, hay fever, hives, allergic rhinitis, allergies) and family lung function tests (Usually less than 6 years of age):
history of atopy or asthma in close relatives.
• Physical exam: should focus on upper respiratory airway NOTE: There are no age criteria for the diagnosis of asthma
(nasopharynx) and lower respiratory airway (chest) as well as as it can be diagnosed at any age. However, caution should be
the skin. Physical exam may help confirm the diagnosis of used when diagnosing asthma in clients less than one year of
asthma, but does not generally provide the diagnosis. Physical age. Persistent respiratory symptoms in infants and children may
exam alone tends to underestimate the severity of an asthma warrant a referral to a specialist.
exacerbation. Co-morbid conditions such as rhinitis, sinusitis, • The diagnosis rests on careful and sometimes repeated history
post nasal drip or Gastroesphageal Reflux Disease (GERD) that taking and physical examination as stated above
mimic or worsen asthma symptoms should be evaluated and *Please note- in children age 6-17 only a ≥ 12% improvement in FEV 1.0 is
addressed. required after bronchodilator.

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1. Diagnosis Asthma

• Factors particularly useful in establishing a diagnosis in young


patients:
• severe episodes of wheezing
• wheezing after 1 year of age
• more than 3 episodes of wheezing in a given year
• family history of asthma/atopy
• personal history of asthma/atopy
• maternal smoking
• clinical benefits from acute bronchodilator therapy
• clinical evidence of improvement after anti-inflammatory
treatment
• chronic cough (especially nocturnal or associated with
exercise)
• wheezing when viral etiology is unlikely

The likelihood of a diagnosis of asthma increases with the number


of these factors present.

Clinical Index for the Diagnosis of Asthma

Stringent Index: 3 or more episodes of wheeze during the first


3 years of life with either one of the major risk
factors: parental history of asthma or eczema, or
2 of 3 minor risk factors; eosinophilia, wheezing
without colds, allergic rhinitis

Loose Index: any wheezing during the first 3 years of life plus 1
major or 2 minor risk factors

Clinical Clues to Alternate Diagnosis

Not asthma: poor response to therapy after ensuring compliance


with trigger avoidance strategies, proper inhaler use and compliance
with medical treatment. No history of atopy.
• Cystic fibrosis: malabsorption, finger clubbing, nasal polyps
• Pertussis: paroxysmal cough, ill contacts
• Rhinitis/Sinusitis: no wheeze, throat clearing
• Gastroesophageal Reflux (GER): previous regurgitation, night
time
• Congenital malformation: age under one year
• Foreign Body: sudden onset without Upper Respiratory Infection
(URI), focal findings

f. Further Testing
• Referral to a medical specialist for bronchoprovocation testing to
help confirm or rule out asthma.
• Appropriate allergy assessment is warranted in patients with
asthma and must be interpreted in light of patient’s history.
Allergen exposure is a risk factor for severe, acute asthma,
especially if the patient is exposed to high concentrations of
the specific allergen. Therefore, allergens to which a person
is sensitized should be identified through allergy testing.
Once identified, steps should be taken to eliminate or at least
substantially reduce allergen exposure.

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1. Diagnosis Asthma

g. Algorithms
Approach to Asthma Diagnosis in Clients Able to Perform Spirometry Tests
Reliably (usually 6 years of age or greater) in the Primary Care Setting

Suspect asthma based on symptoms, patient history & physical exam

Confirm diagnosis of asthma with Pre & Post Spirometry Testing

Is there a >12% improvement in Forced Expiratory Asthma diagnosis confirmed


Volume FEV1.0 (of at least 180ml in adults 18+) 10 YES Initiate treatment & asthma education
minutes after short-acting bronchodilator* (Referral to asthma educator)

NO

Does pre & post spirometry test meet the following criteria to be considered normal
• FEV1.0/FVC ratio > 0.7
• FVC > 80% of predicted value
• FEV1.0 > 80% of predicted value

NO YES

• If FVC is < 80% predicted and Consider diagnosis of restrictive


FEV1.0/FVC ratio is > 0.7 lung defect not consistent with a
diagnosis of asthma - referral to a
• Post bronchodilator FEV1.0/FVC specialist may be warranted
ratio is < 0.7 and post
bronchodilator FEV1.0 is < 80% Diagnosis of COPD can be Initiate proper COPD treatment
predicted confirmed alone or co-existing with
asthma
• If post bronchodilator
FEV1.0/FVC ratio is < 0.7 Consider diagnosis of irreversible
obstructive lung defect

Is client currently symptomatic

YES NO

• Initiate proper asthma therapy of • Repeat spirometry if and when


inhaled corticosteroids and short- symptoms recur to confirm
acting bronchodilators for one month diagnosis of asthma or dismiss
then follow up and reassess diagnosis of asthma

• Clinical benefits after proper asthma


therapy?

YES NO

• Asthma diagnosis may be confirmed


• Consider re-test with spirometry Referral to a specialist for bronchoprovocation testing to help confirm / rule out diagnosis of asthma
• Initiate treatment and asthma and investigate other conditions that mimic asthma (i.e. Gastroesophageal Reflux Disease (GERD),
education (referral to an asthma vocal cord dysfunction)
educator)
years of age. Some children as young as 5 can give
Notes:
reliable spirometry testing. Therefore, this may need
• FVC is forced vital capacity, FEV1.0 is forced to be decided by the person performing the test.
expiratory volume in 1 second.
*• In children age 6 - 17 only a ≥12% improvement in
• Normal predicted values in spirometry are available FEV1.0 10 minutes after a short-acting bronchodilator
for people 5 years of age and older. No normal is required to confirm a diagnosis of asthma.
predicted values exist for children younger than 5

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1. Diagnosis Asthma

Asthma
Approach to Asthma Diagnosis in Clients Able to Perform Peak Expiratory Flow Tests
Reliably (usually 6 years of age or greater) in the Primary Care Setting

Suspect asthma based on symptoms, patient history & physical exam

Spirometry is not available


(Spirometry is the preferred method according to the CPG’s)

Confirm Diagnosis of asthma with Peak Expiratory Flows (PEF)

>20% improvement in PEF 10 minutes after >20% or greater diurnal variability in PEF
administration of short-acting B-2 agonist over a period of several weeks

YES NO YES NO

Asthma diagnosis confirmed Asthma diagnosis confirmed


Initiate treatment and asthma education Initiate treatment and asthma education
(referral to an asthma educator) (referral to an asthma educator)

Is client currently symptomatic

YES NO

Initiate proper asthma therapy of inhaled Repeat PEF if and when symptoms recur
corticosteroids and short-acting bronchodilators
for one month then follow up and reassess

Clinical benefits after proper asthma therapy

YES NO

Asthma diagnosis may be confirmed Consider a referral to have pre & post spirometry done or referral to a
Consider retesting with spirometry specialist for bronchoprovocation test to help confirm / rule out
Initiate treatment and asthma asthma diagnosis and investigate other conditions that mimic asthma
education (i.e. Gastroesophageal Reflux Disease (GERD), vocal cord
Consider a referral to an asthma dysfunction).
educator

Note:
• PEF is less reliable than spirometry for confirming the diagnosis of asthma
To calculate a 20% improvement in PEF following administration of a short-acting B-2 agonist:
1. Obtain a peak flow reading prior to medication, e.g. 400 lpm
2. Multiply that number by 1.2 to give value needed to confirm a 20% improvement in PEF (400 x 1.2 = 480).
3. Give B-2agonist, wait 10 minutes then repeat PEF; this value must be > 480 lpm to show a 20% improvement in
PEF and confirm diagnosis of asthma
To calculate diurnal variation of PEF:
1. Client is to measure peak flows in the am and pm of each day for 2-4 weeks and record the best value of 3 tries
in a diary
2. Once this data has been recorded, calculate the diurnal variation of each day by using the following formula:
Highest PEF – Lowest PEF (on the same day) x 100
Highest PEF
For example: Day 1 Day 2 Day 3
PEF am pm am pm am pm
400 500 400 450 350 500
500 – 400 x 100 450 – 400 x 100 500 – 350 x 100
500 450 500
= 20% diurnal variation = 11.1% diurnal variation = 30% diurnal variation
• Children as young as 5 years of age may be able to properly perform PEF. There are no predicted values for children
under 5 years of age for peak flow.

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January 2006 Building Healthy Lifestyles
1. Diagnosis Asthma
Asthma

Approach to Asthma Diagnosis in Clients Unable to Perform Reliable


Pulmonary Function Tests (less than 6 years of age) in the Primary Care Setting

Suspect asthma based on symptoms, patient history & physical exam

First, determine the presence of airway sensitivity – by inquiring about symptoms such as cough,
wheeze, limited physical activity, chest tightness and shortness of breath.

Second, look for evidence of inherited ability to react to stimuli - is there a family history of atopy
and a personal history of eczema or atopy.

Third, establish that there is no underlying lung disease - look for anything else that could be
causing cough.

Therapeutic trial of asthma medications to confirm diagnosis of asthma in preschool children

Beta-2 agonists for relief of symptoms such as wheeze, chest tightness and shortness of breath (SOB)

AND

Inhaled Corticosteroid for coughing for a period of one month

OR
Oral prednisone for therapeutic trial for coughing, 1mg/kg per day up to a maximum of 50 mg x 5 days

CAUTION: ensure child is not incubating varicella virus. A comprehensive varicella history should be
done

Reassess response to asthma therapy in child


• Did Beta-2 agonist provide relief from wheeze, chest tightness and SOB?
• Did cough subside after one month of inhaled corticosteroids?
• Did cough subside after 5 days of oral prednisone?

YES NO

Asthma diagnosis may be confirmed Consider an alternate diagnosis


especially if symptoms recur when Consider a referral to a Pediatrician
medications are stopped
Initiate treatment and asthma education
Referral to an asthma educator

• NOTE- there is no age criteria for the diagnosis of asthma as it can be diagnosed at any age. However,
caution should be used when diagnosing asthma in children less than one year of age. Persistent
respiratory symptoms in infants and children may warrant a referral to a specialist.

January 2006 Building Healthy Lifestyles


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2. Classification/Type/Staging Asthma

2. Classification/Type/Staging
Determining the Severity of Asthma

Assessment of asthma severity will help physician determine


appropriate level of therapy required, as well as when a client
should be referred to a specialist.

The severity of asthma can be evaluated in two ways:


1. Before or without treatment – which takes into account
symptoms, physiological indicators of airway disease (lung
function tests) and morbidity.
2. With treatment or when controlled asthma amount of
medication required to maintain control.

The primary measure of asthma severity in the treated patient


should be the minimum therapy required to achieve acceptable
control.

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2. Classification/Type/Staging Asthma

Asthma severity before or without proper treatment


Event or measurement Mild Moderate Severe
FEV1.0 or PEF, % of predicted >80% 60 – 79% <60%
Need for short-acting B-2 agonist Every 8 or more h Every 4-8 hours Every 2-4 hours
Night-time symptoms 0 to + + +++
Limitation of daily activities 0 to + + to ++ +++
Probability of:
Recent admission to hospital 0 0 +
Previous near fatal episode 0 0 +

Note: FEV1.0 = Forced Expiratory Volume in 1 second; PEF = Peak Expiratory Flow

0 = none
+ = minimal (infrequent)
++ = moderate (frequent)
+++ = severe (very frequent)

Asthma severity with treatment (controlled)


Asthma severity Symptoms Treatment required for control
Very Mild mild- infrequent none, or inhaled beta-2 agonist rarely (less than 3 times per week)
Mild well-controlled beta-2agonist (occasionally) & low dose inhaled corticosteroids
beta-2 agonist (occasionally) & low to moderate doses of inhaled corticosteroids with
Moderate well-controlled
or without additional therapy
Severe well-controlled beta-2 agonist & high doses of inhaled corticosteroids with add on therapy
beta-2 agonist & high doses of inhaled corticosteroids plus add on therapy plus oral
Very Severe not well-controlled
glucocorticosteroid

Dose equivalencies for inhaled corticosteroids (All ages)


Daily Dose (mcg/day)
Product Low Moderate High
BUD turbuhaler <400 401 - 800 >800
FP pMDI and spacer <250 251 - 500 >500
FP Diskus <250 251 - 500 >500
BDP pMDI (HFA) <250 251 - 500 >500
BUD wet nebulization <1000 1001 - 2000 >2000

BDP = Beclomethasone dipropionate (Q-var)


BUD = Budesonide (pulmicort)
FP = Fluticasone propionate (Flovent)

Note: Children will “auto-scale” their inhaled medication dose, (take proportionately smaller inspiratory volumes compared to adults, which
results in less of the dispensed dose of inhaled medication reaching the lungs). The same dose can be used for all medications at all ages.

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3. Chronic Disease Patient Care Flow Sheet Asthma

3. Chronic Disease Patient Care Flowsheet


Asthma Patient Care Flow Sheet Patient Name

Comorbid Conditions PHN

Year of Diagnosis

DATE: _________ _________ _________ ________ _________ _________


REVIEW ITEMS
Needs reliever medication ≥ 4 times/week
(may use 1 dose/day for exercise)
Physical activity limited by symptoms (in past 3 months)
(Sx: coughing, wheezing or chest tightness)
Symptoms wake patient at night ≥ 1 times/week
Asthma Control
ASTHMA

Symptoms ≥ 4 days/week

Any urgent visits for asthma since last regular appointment

Absence from work/school because of asthma


(in last 3 months)
*Client must answer all with NO to have Control , if Yes to one or more questions asthma is not controlled reassess
REGULAR OFFICE VISITS FOR

Smoker or secondhand smoke in the home/vehicles. If yes


address smoking (ask, advise, assist, arrange 4As)
Trigger Avoidance

Identified asthma triggers:

Have steps been taken to reduce exposure to asthma triggers

A client that is not reducing exposure to allergens and asthma triggers will be difficult to control. Referral to asthma program
Does client have a written asthma action plan
* If not, provide a written CHR asthma action plan

Client understands how to use the asthma action plan


Is controller medication used regularly?
Compliance

Controller medications:

Reliever Medications:

Economic Concerns (cost of meds):

Have patient demonstrate how they use their inhaler device(s)


*Ensure Proper Inhaler Technique
Sx of GERD, Rhinitis, Sinusitis
Comorbidities

Asthma meds that may affect other diseases


(Prednisone use, test blood glucose)
Sx of depression, anxiety

* If any comorbidities exist with asthma, treat appropriately as these may affect proper asthma control
Perform Pre & Post Spirometry testing yearly & prn
Tests

Height and weight (especially for pediatrics)


ANNUALLY

BMD for osteoporosis (If on ICSs and has risk factors)


Review asthma action plan, try to reduce medication required
while maintaining asthma control
Management

Referrals: Asthma educator for education & evaluation


• for initial education & follow up as needed
Medical Specialist – as needed
Vaccinations: Annual Influenza vaccine
Pneumoccocal vaccine if > 65 years
Immunizations up to date
Revised as of May 9, 2005 developed by the BHL/chronic respiratory/ Chinook Health Region

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3. Patient Care Flow Sheet Asthma

Asthma Continuum of Care Reliever (Rescue) medications


� Salbutamol (Ventolin) MDI 100 mcg per dose
� 1 or 2 inhalations as needed
� Salbutamol (Ventolin) Diskus 200 mcg per dose
� Adults & children 6 and older, 1 inhalation as needed
� Terbutaline (Bricanyl) Turbuhaler 0.5 mg per dose
� Adults & children 6 and older, 1 inhalation as needed
� Salbutamol (Airomir) MDI 100 mcg per dose
� 1 to 2 inhalations as needed

Inhaled Corticosteriods (Preventer/controller medications)


ICSs should be introduced as the initial maintenance treatment for asthma,
even in subjects who have very mild asthma and use their reliever
medication less than 3 times/week. Refer to chart on left for proposed
doses for ICSs
� Fluticasone (Flovent) MDI 50, 125 & 250 mcg per dose
� BID dosing most effective
� Fluticasone (Flovent) Diskus 50, 100, 250, 500 mcg per dose
� BID dosing most effective
� Budesonide (Pulmicort) Turbuhaler 100, 200 & 400 mcg per dose
� BID dosing most effective
Daily Long Term Inhaled Steroid Agents and Doses � Beclomethasone (Q-var) MDI 50 & 100 mcg per dose
Mcg/day (all ages) � BID dosing most effective
Product Low Medium High
Add on Therapy if required
BUD Turbuhaler < 400 401 – 800 > 800 If asthma is not controlled by low doses of ICSs, additional therapy
Pulmicort should be considered:
FP pMDI and spacer < 250 251 – 500 > 500 FIRST OPTION – Add long-acting beta2 agonist to existing therapy of
Flovent ICSs and short-acting beta 2 agonists, or replace ICSs with a combination
FP Diskus < 250 251 – 500 > 500 medication.
BDP pMDI (HFA) < 250 251 – 500 > 500 � Salmeterol (Serevent) MDI 25 mcg per dose
Q-var � Adults 1 or 2 inhalations BID
BUD wet nebulization < 1000 1001- 2000 > 2000 � Children 4 years of age and older 1 or 2 inhalations BID
� Salmeterol (Serevent) Diskus 50 mcg per dose
� Adults 1 inhalation BID
Note: children will “auto scale” their inhaled medication dose, (take � Children 6 years of age and older 1 inhalation BID
smaller inspiratory volumes which results in less dose reaching the � Formoterol (Oxeze) Turbuhaler 6 or 12 mcg per dose
lower airways) the same dose can be used for all asthma medications � Adults 1 inhalation of 6 or 12 mcg BID (max 48 mcg per day)
at all ages. � Children 6-16 1 inhalation of 6 or 12 mcg BID (max 24 mcg day)
FP= Fluticasone propionate (GSK Canada Inc) OR
BUD= Budesonide (AstraZeneca Canada Inc) � Advair (Serevent 50 mcg/Flovent 100, 250 & 500 mcg per dose) Diskus
BDP= Beclomethosone dipropionate (3M Pharmaceuticals Canada) � Adults and children 12 and older, 1 inhalation BID
� Children 6-11 years of age, 1 inhalation BID
Asthma Severity based on treatment needed to obtain control � Advair (Serevent 25 mcg/Flovent 125 & 250 per dose) MDI
Asthma Severity Symptoms Treatment required
� Adults and children 12 and older, 1 or 2 inhalations BID
� Children 4 years of age and older, 1 or 2 inhalations BID
Very mild Mild-infrequent None, or inhaled short- � Symbicort (Oxeze 6 mcg/Pulmicort 100 & 200 mcg per dose) Turbuhaler
acting B-2 agonist rarely � Adults and children 12 years of age and older, 1 or 2 inhalations BID
� Children 6 to 11 years of age, 1 or 2 inhalations BID
Mild Well-controlled Short-acting B-2 agonist
(occasionally) and low dose
SECOND OPTION- Increase the inhaled corticosteriods (ICSs) to a
inhaled steroids moderate dosage as per chart or add in a leukotriene receptor antagonist.
� Montelukast (Singulair) 4, 5 & 10 mg chewable tablet
Moderate Well-controlled Short-acting B-2 agonist and � Adults and children 15 years of age and older one 10 mg tablet daily
low to moderate doses of at bedtime
inhaled steroids with or � Children 6 to 14 years of age one 5 mg tablet daily at bedtime
without add on therapy � Children 2 to 5 years of age one 4 mg tablet daily in the evening
� Zarfirlukast (Accolate) 20 mg tablet
Severe Well-controlled Short-acting B-2 agonist and
high doses on inhaled � Adults and children 12 years of age and older two 20 mg tablets daily
steroids and add on therapy THIRD OPTION – consider theophylline, severe asthma may require
additional treatment with Prednisone. If required to maintain control, refer
Very severe May be Short-acting B-2 agonist and to the CPS for dosing requirements & refer to medical specialist.
controlled or not high doses of inhaled
well-controlled steroids and add on therapy Prednisone – for acute exacerbations of asthma, use the following
and oral steroids dosages:
� For ages 12 and over: 50 mg po daily for 3-10 days
� For ages under 12: 1mg/kg po daily for 3-10 days (maximum dose: 2
mg/kg po daily)
No Prednisone dose tapering required if less than 2 weeks

Treatment options from the Canadian Asthma Consensus Guidelines update 2003, medications updated as of January 12, 2006

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4. Management Strategies for Health Teams Asthma

4. Management Strategies for Health Teams


a. Goals of Management • Allergy testing to identify allergens to which a person is
sensitized; once these allergens are identified, steps should
To maintain acceptable asthma control use nonpharmacologic and be taken to eliminate or at least substantially reduce allergen
pharmacologic strategies. Asthma control is defined under Key exposure
Clinical Targets.
• Current recommendations for protecting against development
of allergy and asthma in subsequent pregnancies and subsequent
b. Key Clinical Targets
children:
1. Elimination of exposure to ETS (includes during pregnancy)
Criteria for asthma control 2. Promotion of exclusive breast feeding for at least 4 months
Parameter Frequency or value 3. For families with biparental atopy, maternal asthma or both,
it appears that there is substantive data to recommend against
Daytime symptoms less than 4 days/week the presence of a cat or dog in the home
Night-time symptoms less than 1 night/week
IMPORTANT! Medication should not be substituted for
Physical activity Normal
environmental control and trigger avoidance strategies.
Exacerbations Mild, infrequent
Asthma Action Plan:
Absence from work/school None
• Devise a written action plan for the management of
Need for short-acting beta-2 agonist Less than 4 doses/week*
exacerbations that includes medication adjustment in response
FEV1.0 or PEF > 85% of personal best to changes in severity or frequency of symptoms, the need for
Ideally 90% symptom relief medication or changes in PEF. Provide the
PEF diurnal variation < 15% of diurnal variation written document or ask an asthma educator to do so. Please
refer to Section 5, subsection “a” for a copy of the CHR Asthma
*May use 1 dose/day for prevention of exercise-induced symptoms Action Plan.

To be considered controlled asthma, all the above criteria must Education and Follow-up:
be met. If they are not met, it is then considered uncontrolled
asthma. Education is an essential component of asthma therapy and should
be offered to all patients. Educational interventions may be of
Control can be achieved in uncontrolled asthma through patient particular benefit to patients with high asthma-related morbidity or
education, trigger avoidance and medications. severe asthma and at the time of emergency department visits and
admissions to hospital.
• All patients should self-monitor their asthma using symptoms or
PEF or both
• Ensure regular follow-up (every 6 months). Asthma control
criteria should be assessed at each visit. Measurement of
pulmonary function, preferably spirometry, should be done
regularly in adults and children 6 years of age and older. Review
written action plan and medication required with an aim to
reduce amount of medication while maintaining asthma control.

Smoking Cessation:
• Smoking cessation interventions (4A model) should be offered
to patients who smoke, or parents of children with asthma who
smoke.

c. Non-Pharmacologic Strategies for Asthma Influenza vaccination:


• All patients with asthma should be encouraged to have an annual
Environmental Control:
influenza vaccination, as well as any family members living with
• Elimination of exposure to environmental tobacco smoke (ETS) patient (parents & siblings).
• Identification of asthma triggers and implement trigger
avoidance strategies

Chinook Health Region 15 Building Healthy Lifestyles


4. Management Strategies for Health Teams Asthma

Immunotherapy in Adults: Inhaled Corticosteroids (ICSs) low dose – maintenance


• Immunotherapy is generally not recommended in the treatment • Regular use of low dose ICSs is currently the recommended
of asthma treatment for persons with asthma of all ages, even for those
• Immunotherapy should not be used in place of avoidance of with intermittent asthma symptoms
environmental allergens • Physicians should recommend that children with frequent
• Immunotherapy with clinically relevant allergens may be symptoms, severe asthma exacerbations or both receive regular,
considered if disease activity is inadequately controlled by not intermittent, treatment with ICSs
avoidance of allergens and pharmacotherapy • The use of intermittent treatment as a strategy for management
• Immunotherapy should be avoided while asthma is poorly of intermittent asthma in childhood is not validated and requires
controlled further research especially in very young children

• Well-controlled asthma is not a contraindication for • For patients who cannot or will not use ICSs, leukotriene
immunotherapy for allergic rhinoconjunctivitis or insect venom receptor antagonists (LTRAs) should be the primary treatment
hypersensitivity choice, although they are less effective than low dose ICSs
• Fluticasone (Flovent) MDI 50, 125 & 250 mcg per dose
• Immunotherapy must be administered only by trained personnel ○ BID dosing most effective
in centres where there is medical supervision and resuscitative
equipment (for both children & adults) • Fluticasone (Flovent) Diskus 50, 100, 250, 500 mcg per dose
○ BID dosing most effective
Immunotherapy in Children:
• Although debate about the value of immunotherapy continues, • Budesonide (Pulmicort) Turbuhaler 100, 200 & 400 mcg per
meta-analysis and review of immunotherapy support the dose
potential value of immunotherapy in childhood; early ○ BID dosing most effective
immunotherapy may prevent development of asthma in children • Beclomethasone (Q-var) MDI 50 & 100 mcg per dose
sensitized to house dust mite allergen ○ BID dosing most effective
• Physicians should consider injection immunotherapy using
appropriate allergens for the treatment of allergic asthma only
when allergic component is well documented
• Physicians should not recommend the use of injection
immunotherapy in place of avoidance of environmental allergens
• Physicians may consider injection immunotherapy in addition to
appropriate environmental control and pharmacotherapy when
asthma control remains inadequate
• Immunotherapy is not recommended when asthma is unstable

d. Pharmacologic Strategies for Asthma


First Line Therapy:

Reliever medications – rescue


• Salbutamol (Ventolin) MDI 100 mcg per dose
○ 1 or 2 inhalations as needed
• Salbutamol (Ventolin) Diskus 200 mcg per dose
○ Adults 1 inhalation as needed
○ Children 6 years and older 1 inhalation as needed
• Terbutaline (Bricanyl) Turbuhaler 0.5 mg per dose
○ Adults 1 inhalation as needed
○ Children 6 years and older 1 inhalation as needed
• Salbutamol (Airomir) MDI 100 mcg per dose
○ 1 to 2 inhalations as needed

AND

Chinook Health Region 16 Building Healthy Lifestyles


4. Management Strategies for Health Teams Asthma

Dose equivalencies for inhaled corticosteroids - ICSs (All ages)


Daily Dose (mcg/day)
Product Low Moderate High
BUD turbuhaler < 400 401 - 800 > 800
FP pMDI and spacer < 250 251 - 500 > 500
FP Diskus < 250 251 - 500 > 500
BDP pMDI (HFA) < 250 251 - 500 > 500
BUD wet nebulization < 1000 1001 - 2000 > 2000

BDP= Beclomethasone dipropionate (Q-var)


BUD= Budesonide (Pulmicort)
FP= Fluticasone propionate (Flovent)
* Note: Children will “auto-scale” their inhaled medication dose, (take proportionately smaller inspiratory volumes compared to adults, which
results in less of the dispensed dose of inhaled medication reaching the lungs). The same dose can be used for all medications at all ages.

Add on Therapy as Required: SECOND OPTION- Increase the inhaled corticosteroids (ICSs)
• If after reassessment of compliance with treatment, trigger to a moderate dosage as per chart or add in a leukotriene receptor
avoidance strategies, inhaler technique and co-morbidities, antagonist (LTRAs)
asthma is not controlled by low dose ICSs, additional therapy • Montelukast (Singulair) 4, 5 & 10 mg chewable tablet
should be considered: ○ Adults and children 15 years of age and older one 10 mg
tablet daily at bedtime
FIRST OPTION – Add long-acting beta-2 agonist to existing ○ Children 6 to 14 years of age one 5 mg tablet daily at
therapy of ICSs and short-acting beta-2 agonist, or replace ICSs bedtime
with a combination medication. ○ Children 2 to 5 years of age one 4 mg tablet daily in the
• Salmeterol (Serevent) MDI 25 mcg per dose evening
○ Adults 1 or 2 inhalations BID • Zarfirlukast (Accolate) 20 mg tablet
○ Children 4 years of age and older 1 or 2 inhalations BID ○ Adults and children 12 years of age and older two 20 mg
• Salmeterol (Serevent) Diskus 50 mcg per dose tablets daily
○ Adults 1 inhalation BID
○ Children 6 years of age and older 1 inhalation BID THIRD OPTION – Consider theophylline; severe asthma may
require additional treatment with prednisone. If required to
• Formoterol (Oxeze) Turbuhaler 6 or 12 mcg per dose maintain control, refer to the CPS for dosing requirements and
○ Adults 1 inhalation of 6 or 12 mcg BID (max 48 mcg per refer to a medical specialist.
day)
○ Children 6-16 1 inhalation of 6 or 12 mcg BID (max 24 Prednisone:
mcg day)
For acute exacerbations of asthma, use the following dosages:
OR • For ages 12 and over: 50 mg po daily for 3-10 days
• Advair (Serevent 50 mcg/Flovent 100, 250 & 500 mcg per dose) • For ages under 12: 1mg/kg po daily for 3-10 days (maximum
Diskus dose: 2 mg/kg po daily)
○ Adults and children 12 and older, 1 inhalation BID
○ Children 6-11 years of age, 1 inhalation BID No Prednisone dose tapering required if less than 2 weeks
• Advair (Serevent 25 mcg/Flovent 125 & 250 per dose) MDI
○ Adults and children 12 and older, 1 or 2 inhalations BID
○ Children 4 years of age and older, 1 or 2 inhalations BID
• Symbicort (Oxeze 6 mcg/Pulmicort 100 & 200 mcg per dose)
Turbuhaler
○ Adults and children 12 years of age and older, 1 or 2
inhalations BID
○ Children 6 to 11 years of age, 1 or 2 inhalations BID

Chinook Health Region 17 Building Healthy Lifestyles


4. Management Strategies for Health Teams Asthma

Management of Acute Asthma Exacerbations (excluding ER and • There is some evidence for the potential benefit of a more
acute care facilities) substantial increase in the dose of ICS such as tripling or
quadrupling the regular maintenance dose at the first sign of an
Acute asthma exacerbation – is defined as deterioration of asthma asthma exacerbation.
control that is not responding to B-2 agonist rescue treatment in
the usual manner or a sustained worsening of asthma symptoms • The standard of care is that ICS dose should be increased during
leading to increased use of B-2 agonists as well as increased use of an asthma exacerbation, but there is not enough good evidence
maintenance medications and/or supplementation with additional to make a generic recommendation as what dose to increase the
medicine. The following are loose criteria that can define an acute ICS from the maintenance dose during the exacerbation.
asthma exacerbation: • Through the COPD & Asthma Network of Alberta (CANA),
• Bronchodilator use ≥ 4 times/week (excluding 1 dose/day for as well as consulting local CHR specialists we have summarized
exercise) current clinical practices utilized by both pediatric and adult
respiratory specialists throughout Alberta in managing acute
• Nocturnal awakenings due to asthma ≥ 2 times/week asthma exacerbations:
• Daytime asthma symptoms ≥ 4 days/week ○ If the client is on high doses of ICS for maintenance
(or maximum daily dosage for that client as decided by
• Recent absence from work or school due to asthma
physician), the clinical practice is to double the maintenance
• Recent unscheduled physician visit due to asthma dose of ICS or maintain the current dose of ICS and add in
• Spirometry testing shows FEV1.0 < 80% of predicted normal a long-acting beta agonist (LABA) or leukotriene receptor
antagonist (LTRA) for a period of approximately 2 weeks.
• PEF tests fall below 80% of personal best value, or predicted ○ If client is on low to moderate doses of ICS for maintenance,
value if personal best is not known the clinical practice is to increase to the full dose of the
• Studies have shown that the major cause (80%) of asthma specific ICS for approximately 2 weeks, then return to
exacerbations is viral upper respiratory infections. With viral maintenance dose.
upper respiratory infections the inflammatory response tends to
be more neutrophilic than eosinophilic. Inhaled corticosteroids Full dose:
may not be effective during neutrophilic inflammatory responses
Fluticasone (Flovent) 500 – 1000 mcg/day
seen with viral upper respiratory infections.
Beclamethasone (Q-Var) 400 – 800 mcg/day
Non-Pharmacologic Strategies: Budesonide (Pulmicort) 800 – 1600 mcg/day
• Avoid contact with environmental tobacco smoke ○ The clinical practice of many respiratory specialists is to
• Continue to avoid personal asthma triggers increase the dose of ICS at the first sign of an exacerbation
and whether the dose is doubled or quadrupled depends on
• Refer to personalized written asthma action plan as to how to the client’s maintenance dose as well as personal history of
temporarily modify asthma medications exacerbations. Those who become ill quickly upon exposure
Pharmacologic Strategies: to triggers treat more aggressively than those who generally
manage trigger exposure without significant incident.
• Prevention of asthma exacerbations needs to be the primary ○ If the asthma exacerbation is not responding to increased
target of asthma treatment and ICSs. This can be accomplished doses of ICS and add on therapy, a short course of oral
through regular use of ICSs as maintenance treatment for prednisone should be considered. Recommended doses:
asthma.
• Previous asthma guidelines have recommended the use of an For ages 12 and over: 50 mg po daily for 3-10 days
action plan to manage asthma exacerbations. Many of these For ages under 12: 1mg/kg po daily for 3-10 days
plans advocate a doubling of the dose of maintenance ICS as (maximum dose: 2 mg/kg po daily)
one of the first steps in the management of worsening asthma.
However, there are no randomized controlled trials to support No Prednisone dose tapering required if less than 2 weeks
doubling the dose of ICS on identification of exacerbations of
asthma.
The above evidence is based on the opinions of those who have written
• 2 recent studies (adult & pediatric populations) have provided and reviewed the asthma guidelines, based on their experience,
evidence that early or impending asthma exacerbations are knowledge of the relevant literature and discussion with their peers.
not always effectively treated by doubling the dose of inhaled
corticosteroids at the first sign of an exacerbation. These results
apply to those patients with asthma who regularly use their
preventer or controller medication as maintenance therapy when
well.

Chinook Health Region 18 Building Healthy Lifestyles


4. Management Strategies for Health Teams Asthma

Special Considerations: • Physicians should discuss medication choices and the rationale
for treatment plan; they should emphasize that the treatment
Asthma in the Elderly program is considered to entail less risk than the uncontrolled
illness that could result in its absence.
Diagnosis
• The use of systemic glucocorticosteriods for severe asthma,
• A diagnosis of asthma should be more widely considered in
especially for prolonged periods, may be associated with a greater
elderly patients with dyspnea, wheezing or nocturnal cough.
risk of pre-eclampsia, antepartum or postpartum hemorrhage,
Asthma may be difficult to diagnosis in the elderly because of
low birth weight, preterm birth and hyperbilirubinemia.
misconceptions about its prevalence and also because older
patients have diseases and disorders that mask the classic features • Patients requiring systemic glucocorticosteroid therapy should be
of asthma. considered to be in a higher risk pregnancy.

Treatment Treatment
• In the elderly patient with asthma, it is particularly important to • Avoidance of allergic and non-allergic triggering factors should
take a careful medication history. Use of self-prescribed ASA has be the first form of therapy for asthma during pregnancy.
become common and may go unrecognized. ASA and NSAIDS • Treatment should take the same approach as the non-pregnant
are commonly prescribed in the elderly and may cause late-on- patient and may include inhaled B-2 agonists, inhaled
set asthma. Oral and topical B-adrenergic blocking agents and corticosteroids, ipratropium bromide, cromolyn and systemic
other anti-arrhythmic agents, including verapamil and others steroids. Theophylline may increase nausea and reflux and is less
with acknowledged B-blocker potential, can exacerbate or cause desirable. There is significantly less information about the effects
asthma in those who are predisposed to the disease. Whenever of long-acting B-2 agonists and leukotriene inhibitors and there
possible, medications that might induce or aggravate asthma is less clinical experience with these drugs than with other classes
should be withdrawn. of drugs. These drugs should be used only for patients whose
• Special care should be taken to allow elderly patients with asthma asthma cannot be controlled using the more studied therapies.
to choose an inhaler device with which they are both comfortable • For drugs with a longer history of usage, there tends to be more
and competent. data to support a lack of adverse effects. Use of most common
• Measures should be taken to prevent osteoporosis in elderly asthma medications (B-2 agonists, theophylline, cromolyn,
patients with asthma who require prolonged treatment with oral inhaled glucocorticosteroids) during pregnancy has not been
corticosteroids. shown to be associated with increased perinatal risks including
congenital malformations.
• Elderly patients with asthma require careful follow-up because
they have an increased risk for exacerbations, which may be • Although no asthma medications can be considered proven
related to impaired perception of their disease severity. safe for use during pregnancy, the ones listed above are used
to prevent the potential direct and indirect consequences of
Asthma in Pregnancy uncontrolled asthma.
• Asthma is present in 4 – 7 % of pregnant women and is the • The patient must be aware of the risks and benefits of
respiratory disorder that most frequently complicates pregnancy. appropriate asthma control and must give her informed consent
• The course of asthma during pregnancy is variable and asthma to the therapeutic approach recommended during pregnancy.
control may remain unchanged or become worse or improve
and return to the pre-pregnancy state within 3 months after
parturition.
• Overall, asthma control improves significantly in the last 4 weeks
of pregnancy.
• Asthmatic, pregnant women have been variably reported to
have an increased risk of pregnancy-induced hypertension, pre-
eclampsia, caesarean section, placenta previa and antepartum or
postpartum hemorrhage.

Recommendations
• Do not stop asthma therapy during pregnancy. Poorly controlled
asthma may affect maternal comfort, safety and pregnancy
outcome for both mother and child. Several well designed
studies have shown fewer adverse infant and maternal outcomes
than those without therapy.

Chinook Health Region 19 Building Healthy Lifestyles


4. Management Strategies for Health Teams Asthma

Inhalation Devices for drug delivery In Asthma

Metered Dose Inhalers (MDIs)

Metered Dose Inhalers can be used with any age group. A spacer or
chamber should be used with children and elderly adults. A spacer
should also be used if patient is receiving inhaled corticosteroids.
• Under one year of age - a valved spacer and face mask should be
used with MDI. (orange infant aerochamber with face mask)
• From 2 to 6 years of age - a valved spacer and face mask should
be used with MDI. (yellow pediatric aerochamber with face
mask)
• More than 6 years of age - a valved spacer with a mouthpiece
should be used, rather than a face mask. (blue aerochamber)
• Try to use a valved spacer with mouthpiece in children at the
earliest age it becomes feasible. This will eliminate breathing
through the nose and maximize the chance of increased airway
deposition in the lungs. It has been clearly shown in children
that breathing through a mask via the nose decreases lung
deposition by up to 67% compared with breathing through a
mouthpiece using a jet nebulizer.

Dry Powder Inhalers (DPIs)

Dry Powder Inhalers can be used by most patients by the time they
reach 5 years of age. Spacer devices are not required with these
devices. The two devices in Canada are the Turbuhaler and the
Diskus inhaler.

MDIs vs Nebulizers:

Wet nebulizers for home use are rarely indicated in the


management of asthma at any age. The wet nebulizer device is
cumbersome and expensive and for the amount of medication
delivered the most costly of all methods.

Three meta-analyses of studies in children and adults evaluating


MDI and wet nebulization indicate that the use of MDI with
a chamber or spacer is associated with a more rapid onset of
bronchodilation, shorter duration of emergency department
treatment, fewer side effects and greater patient preference. More
rapid and profound bronchodilation is achieved when sufficient
doses are given with an MDI plus spacer than when conventional
doses are administered with a wet nebulizer.

Note: Proper inhaler technique must be taught to client. Referral


to an asthma education program can ensure this is done. There are
devices available to measure inspiratory flow rate to ensure patient
can adequately use a DPI.

Chinook Health Region 20 Building Healthy Lifestyles


5. Management Strategies for Patients / Clients Asthma

5. Management Strategies for Patients / Clients

ASTHMA ACTION PLAN Patient Name:


(Last and First) _______________________________
Update yearly and as needed
Date of Birth: _________________________________

GREEN ZONE Action:


• Avoid your personal asthma triggers
• Avoid tobacco smoke exposure
YOUR ASTHMA IS IN GOOD CONTROL IF: • Yearly flu immunization
• Watch for asthma symptoms
• You do not wheeze, cough, feel tight or have
• If you have symptoms with exercise take
trouble breathing with your usual activities, ___________ 15 minutes beforehand and remember
with exercise, or at night. to warm up and cool down with exercise
• You require your reliever medicine less than • Check your peak flow _______ per day
three times per week • Controller(s): ____________________________
Your peak flow is
____________________________
between ________ and ________
(80% to 100% of personal best) • Reliever(s): ____________________________
• Personal best or predicted peak flow _______
____________________________

• Other Actions: ____________________________

Action:
YELLOW ZONE
• Avoid your personal asthma triggers
YOUR ASTHMA CONTROL IS DECREASING IF: • Avoid tobacco smoke exposure
• Check your peak flow _______ per day
• You wheeze, cough, feel tight or have if not already doing so
trouble breathing with your usual activities,
• Controller(s): ____________________________
with exercise or at night
• You develop cold symptoms ____________________________
• You require your reliever medicine more than • Reliever(s): ____________________________
three times per week
____________________________
• Your peak flow is
between ________ and ________ • Other Actions: ____________________________
(60% to 80% of personal best)
____________________________
• Seek medical attention if your asthma control is
not improving within 2 or 3 days

Action:
ORANGE ZONE • Avoid your personal asthma triggers
• Avoid tobacco smoke exposure
YOUR ASTHMA IS OUT OF CONTROL IF: • Check your peak flow _______ per day
if not already doing so
• You wheeze, cough, feel tight or have
trouble breathing even at rest • Controller(s): ____________________________
• Your symptoms are interrupting your sleep
____________________________
• You require your reliever medicine more than
four times in twenty four hours • Reliever(s): ____________________________
• Your peak flow is below _________ ____________________________
(60% of personal best)
• Other Actions: ____________________________

____________________________
• Seek medical attention if your asthma control is
not improving within 12-24 hours

RED ZONE
Action:
• Call 911 or go to the nearest emergency department
YOU ARE IN THE DANGER ZONE IF: immediately
• You can repeat your reliever medicine every ____
• You are getting little relief to no relief in 20
minutes times ____ doses while assistance is being
to 30 minutes after your reliever medicine
arranged
• You are struggling to breathe or having
trouble walking or talking
• Your lips or fingernails are turning blue

Prepared by: Appointments:


______________________________M.D./RT/CAE Date: ____________
Physician Signature:____________________________________________
FC-532-01/06 adapted with permission: Alberta Lung Association White: Chart Canary: Patient Pink: Physician

Chinook Health Region 21 Building Healthy Lifestyles


Asthma

Chinook Health Region 22 Building Healthy Lifestyles


5. Management Strategies for Patients / Clients Asthma

YOU HAVE JUST BEEN TOLD THAT YOU OR


YOUR CHILD HAS ASTHMA, NOW WHAT?
WHAT IS ASTHMA? IS ASTHMA A LIFELONG CONDITION?

Asthma is an inflammatory disease of the small airways in the As a general rule, asthma diagnosed in childhood is a lifelong
lungs that results in recurring episodes of difficult breathing due to condition. Asthma symptoms may diminish in adolescence, but
the airways becoming more narrow (smaller) than normal. These can often return in adulthood. People with the following factors
episodes may occur quite often or may come and go intermittently. are most likely to have asthma that persists into adulthood:
Asthma ranges from very mild to severe. • A parent with asthma
WHAT ARE THE SYMPTOMS OF ASTHMA? • A history of eczema (scaly red rashes on the skin)

When the small airways in lungs begin to narrow, people with • Allergies or hay fever; allergic rhinitis (inflammation of the lining
asthma usually notice some or all of the following problems: in the nose)

• Coughing THE GOOD NEWS FOR PEOPLE WITH ASTHMA:


• Wheezing • Researchers are constantly seeking a cure. In the meantime,
• Chest tightness asthma can be controlled. If asthma is well controlled, there is
a low risk for a serious asthma episode and a person can be as
• Shortness of breath active as they like.
• Reduced ability to exercise • To control asthma you need to avoid contact with things that
trigger your asthma and use your asthma medications regularly as
WHAT CAUSES AN ASTHMA EPISODE?
directed by your doctor.
(See diagram on back of this page)
• There are people with well-controlled asthma who are OLYMPIC
• First, a “trigger” is inhaled into the lungs and irritates the small
ATHLETES!
airways in the lungs.
• Once the small airways are irritated, the insides of the airways WHO WILL HELP YOU TO MANAGE YOUR ASTHMA?
become red, swollen and narrower than normal. If nothing is • Your family doctor will diagnose and help manage your or your
done about the swelling it can get worse and people tend to child’s asthma and should provide you with a written asthma
develop more asthma symptoms. action plan.
• Due to the swelling, the small airways in the lungs become quite • Your pharmacist can also provide helpful information about
“twitchy”. This causes the muscles on the outside of the airway asthma and asthma medications.
to tighten and narrow the airways even more. Breathing becomes
much harder than normal at this point and could lead to a • The Chinook Asthma Program is where you will meet with
serious asthma episode. asthma educators who can perform breathing tests to make sure
your lungs are working at their best as well as provide you with
• Asthma episodes, like asthma itself, can range from mild to information about asthma and asthma medications. The asthma
severe. Severe asthma episodes can be life threatening and can educators will work with your doctor to develop a written
result in a hospital stay or even death. Therefore, prevention of asthma plan and ensure you have the tools and confidence to feel
episodes is very important. at ease managing your or your child’s asthma.
• Common asthma triggers are smoke, colds, animal dander, dust, • To contact an asthma educator in your community, contact the
pollen, cold air and exercise. Please note that exercise should Building Healthy Lifestyles toll-free number at 1-866-506-6654
not be avoided. If you or your child develops asthma symptoms or 388-6654.
with exercise, it may be a sign that your or your child’s asthma
is poorly controlled. Contact a healthcare professional to learn
how to improve asthma control. Triggers vary from person to
person. Each person should learn about their own triggers and
try to prepare for them and avoid them when possible.

Chinook Health Region 23 Building Healthy Lifestyles


5. Management Strategies for Patients / Clients Asthma

What is asthma?
As the swelling in the airway increases,
the lining of the airway becomes very
sensitive and small muscles around it
start to twitch and tighten. 6 Emergency room visit

5 Muscles around
airway tighten

coug
g
g
cough

1 Normal airway =
normal function h ee
w he ezze

2 Something starts
inflammation

3 Inflammation of
airway and mucous

Reprinted with permission from the


Asthma Society of Canada
www.asthma.ca
www.asthma-kids.ca

Chinook Health Region 24 Building Healthy Lifestyles


5. Management Strategies for Patients / Clients Asthma

Client Checklist for Asthma


 What to expect at each office visit with your family physician:
Assess asthma control:

Discuss frequency of asthma symptoms

Amount of rescue medication required (blue inhaler usage)

Review triggers and trigger avoidance strategies

Demonstrate use of inhaler device

Make or review a written asthma action plan

Discuss roles and use of asthma medications

Aim to reduce asthma medication dosage while maintaining proper control of asthma

Discuss any other concerns about asthma with your doctor

Tests & Measurements that should be done or discussed on a yearly basis,


 or as recommended by your family physician:
Lung function testing (spirometry)

Height and weight measurements

Screening for osteoporosis if on inhaled corticosteroids for asthma and you have the following risk factors:
• Age > 60 years
• Postmenopausal state without hormone replacement therapy
• Male impotence or infertility
• Previous fractures with minor trauma
• Family history of fractures (parental)
• Past or current chronic glucocorticoid therapy
• Smoking or alcoholism
• Physical inactivity

Referral to an Asthma educator for education & evaluation

Vaccinations

Annual influenza vaccine

Ensure immunizations are up to date

Chinook Health Region 25 Building Healthy Lifestyles


Asthma

Chinook Health Region 26 Building Healthy Lifestyles


6. Indications for a Referral to Medical Specialist or Specialty Program Asthma

6. Indications for a Referral to Medical Specialist or Specialty Program


a. and b. Indications for Referral to Medical Key contacts in the CHR for Asthma:
Specialists and Specialty Programs
Adult Specialists
The following circumstances warrant a referral to an appropriate
Dr. Eric Wilde, Telephone 320-0633
specialist:
• There is doubt about the diagnosis of asthma Pediatric Specialists
• Factors, including aeroallergens and occupational exposures, Dr. K. Chan, Telephone 328-8101
could be involved and have not been properly evaluated; or Dr. M. Harilal, Telephone 320-2236
suspected occupational asthma Dr. J. Holland, Telephone 320-7825
• Asthma is severe according to severity rating criteria
Lethbridge Educators
• There is an apparent discrepancy between the severity of
symptoms and success of treatment Pediatric Asthma clinic, Telephone 388-6180
• There has been a need for emergency treatment or hospital Adult Asthma Clinic, Telephone 388-6180
admission
Rural Educators
• Any persistent respiratory symptoms in infants (under 1 year of
age) and young children (age 1-6) Taber Asthma program, Telephone 223-3525
Cardston Telephone 653-4411
• Normal spirometry tests and/or peak flows, but client requires
Magrath Telephone 758-4411
excessive medication for symptom control or fails to respond
Pincher Creek, Telephone 627-1234
to therapy after the clinician has confirmed compliance with
Crowsnest Pass, Telephone 562-2831
treatment and proper inhaler device technique
Fort Macleod, Telephone 553-5311
Raymond, Telephone 752-4561
c. Local Contacts Milk River, Telephone 647-3500
In the CHR the primary care physicians would refer their adult Picture Butte, Telephone 732-4762
patients to see Dr. Wilde. Once the specialist has seen the client,
By contacting Building Healthy Lifestyles 388-6654 or
they will book additional tests as they see fit.
1-866-506-6654 an appointment can be booked for the patient
Dr. E. Wilde, Specialist Internal & Respiratory Medicine and BHL will notify the appropriate asthma educator.
phone 320-0633
Clinical Guides are available on-line at:
In the CHR the primary care physicians would refer their pediatric
www.chinookprimarycarenetwork.ab.ca/extranet/resources/guides.php
patients to see the following pediatricians:

Dr. K. Chan, Telephone 328-8101


Dr. M. Harilal, Telephone 320-2236
Dr. J. Holland, Telephone 320-7825

Or

The primary care physician could refer pediatric clients to the


Lethbridge Pediatric Asthma Clinic. A pediatrician will assess and
make recommendations for each child who attends the clinic. The
primary care physician would complete a referral form and fax it to
the Building Healthy Lifestyles Program.

Telephone: 388-6654 or 1-866-506-6654


Fax: 317-0435

Chinook Health Region 27 Building Healthy Lifestyles


Asthma

Chinook Health Region 28 Building Healthy Lifestyles


7. References Asthma

7. References
a. Evidence
1. Becker, Allan, MD; Berube, Denis, MD; Montgomery, Mark, MD; Sears, Malcolm, MD; Spier, Sheldon, MD; on behalf of
the Canadian Pediatric Asthma Consensus Guidelines 2003 (updated to December 2004) Supplement to CMAJ 2005; 173
(6 suppl): S1-S56
2. Boulet,Louis-Philippe, MD; Becker, Allan, MD; Berube, Denis, MD; Beveridge,Robert, MD; Ernst, Pierre MD; on behalf
of the Canadian Asthma Consensus group. Canadian Asthma Consensus Report 1999. Supplement to CMAJ 1999; 161
(11 suppl)
3. British Columbia Guidelines & Protocols Advisory Committee, Diagnosis and Management of Asthma July 1, 2003
4. FitzGerald JM, Becker A, Sears MR, et al. Doubling the dose of budesonide versus maintenance treatment in asthma
exacerbations. Thorax 2004;59:550-6
5. Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled
trial. Lancet 2002; 360:1715-21
6. Harrison TW, Oborne J, Newton S, et al. Doubling the dose of inhaled corticosteroid to prevent asthma exacerbations:
randomised controlled trial. Lancet 2004;363:271-5
7. Jarjour NN, Gern JE, Kelly EA, et al. The effect of an experimental rhinovirus 16 infection on bronchial lavage neutrophils.
J Allergy Clin Immunol 2000;105:1169-77
8. Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in
9-11 year old children. BMJ 1995;310:1225-9
9. Lemiere,C; Bai,T; Balter, M, et al, on behalf of the Canadian Adult Consensus group of the Canadian Thoracic Society.
Adult Asthma Consensus guidelines update 2003. Can Respir J 2004; 11 (Suppl A); 9A – 18A
10. Respiratory Division, Cardio-Respiratory diseases and diabetes bureau, laboratory centre for disease control, Health Canada.
The national asthma control task force. The prevention and management of asthma in Canada 2000

b. On-line Resources
1. Canadian Lung Association www.lung.ca
2. Canadian Thoracic Society www.lung.ca/cts/
3. COPD & Asthma Network of Alberta (CANA) www.canahome.org
4. Family Physicians Airways Group of Canada www.fpagc.com
5. Canadian Network for Asthma Care (CNAC) www.cnac.net
6. Child Asthma Network iCan www.calgaryhealthregion.ca/ican/
7. National Institute of Health www.nhlbi.nih.gov
8. Canadian Society of Allergy & Clinical Immunology www.csaci.medical.org
9. Global Initiative for Asthma www.ginaasthma.com
10. Calgary Allergy Network www.calgaryallergy.ca
11. American Academy of Allergy, Asthma & Immunology www.aaaai.org
12. Asthma Society of Canada www.asthma.ca

Available CHR Resources


Winning with Asthma www.chr.ab.ca

Chinook Health Region 29 Building Healthy Lifestyles

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