DRUG STUDY

GENERIC DOSA CLASSIFICATI INDICATION CONTRAINDICATI ADVERSE NURSING

NAME/ GE/ ON ON REACTIONS RESPONSIBILITIES
BRAND ROUTE
NAME
Generic Gout Primary • Allopurinol allergic skin • monitor serum uric
name: Preparations uncomplicated should be reactions, GI acid levels to evaluate
hyperurecemia; discontinued at disturbances, drug’s effectiveness
Allopurinol 100 mild gout; severe the first diarrhea, and joint • monitor fluid
tophaceous gout; pain intake and output; daily
mg OD appearance of
urine output of at least 2
Brand uric acid rash or any liters and maintenance of
name: nephropathy; uric sign that may neutral or slightly alkaline
acid nephrolithiasis; indicate an urine are desirable
LLANOL and in the allergic • periodically
prevention of renal reaction, monitor CBC and hepatic
Calcium oxalate painful and renal function,
stones. especially at start of
urination, blood
therapy, as ordered
in the urine,
• If renal
irritation of the insufficiency occurs at any
eyes, or time during treatment, be
swelling of the prepared to reduce
lips or mouth dosage, as ordered.
• Allopurinol • Optimal benefits
may increase may require 2-6 weeks of
therapy. Because acute
the frequency gouty attacks occur during
of acute gouty this time, concurrent use of
attacks during colchicines may be
the first 6-12 prescribed prophylactically.
months of • To minimize GI
therapy. disturbance, tell patient to
Prophylactic take with or immediately
after meals.
doses of
colchicine • Encourage the
patient to drink plenty of
should fluids while taking this drug
therefore be unless otherwise
administered contraindicated.
concurrently • Drug may cause
during the first drowsiness, tell patient not
3 - 6 months of to drive or perform
hazardous tasks requiring
allopurinol
mental alertness until CNS
therapy. effects of the drug are
• Drowsiness known.
may occur • If the patient is
during taking allopurinol for
allopurinol treatment of recurrent
therapy and calcium oxalate stones,
advise him to also reduce
may impair his dietary intake of animal
one's ability to protein, sodium, refined
perform sugars, oxalate-rich foods,
activities and calcium.
requiring • Tell patient to
mental discontinue at first sign of
alertness. rash, which may precede
severe hypersensitivity or
• Liver other adverse reaction.
function tests Rash is more common in
(particularly in patient taking diuretics and
patients with in those with renal
preexisting disorders. Tell the patient
to report all adverse
liver disease), reactions.
renal function
tests
(particularly in
patients with
impaired renal
function), and
complete blood
cell counts
should be
performed
during the first
few months.
Reduce the
dosage of
allopurinol or
totally
discontinue the
drug if
evidence of
deterioration in
renal function
occurs and
persists.
• Allopurinol
is rarely
indicated in
children except
in those with
hyperuricemia
secondary to
neoplastic
disease, cancer
chemotherapy,
or genetic
disorders of
purine
metabolism.
• The effect
of allopurinol
on the human
fetus is not
known, and the
drug should be
used during
pregnancy only
when clearly
needed.

• Since
allopurinol and
oxypurinol are
distributed into
milk, allopurinol
should be used
with caution in
 nursing women.
Generic regular treatment of • Abdominal • Taper systemic
Name: 160m Corticosteroids asthma where use Hypersensitivity to pain, steroids carefully
budesonide g neb of a combination inhaled lactose conjunctivitis during transfer to
and (inhaled (pinkeye), inhalational steroids;
formoterol corticosteroid and • cough, deaths from adrenal
inhalation long acting beta 2 • diarrhea, insufficiency have
agonist) is • ear infection occurred.
Brand appropriate or
Names: inflammation, • Arrange for use of
Symbicort decongestant nose
• fever,
drops to facilitate
• fungal
penetration if
infection in
edema, excessive
mouth,
secretions are
• headache,
present.
• nasal or sinus
inflammation, • Prime unit before
• nosebleed, use for Pulmicort
• pain, rash, Turbuhaler; have
• respiratory patient rinse mouth
infection, after each use.
• stomach or
intestinal • Use aerosol within
inflammation, 6 mo of opening.
• throat Shake well before
inflammation, each use.
• viral
infection, • Store Respules
• vomiting, upright and
• wheezing protected from light;
gently shake before
use; open envelopes
should be discarded
after 2 wk.

Generic Bronchodilators management of Hypertrophic Fine tremor of • Use nebulizer

name: Neb reversible obstructive skeletal muscle; mouthpiece instead of
ALBUTEROL q6 bronchospasm cardiomyopathy or palpitations; face mask to avoid
SULFATE associated with tachyarrhythmia. headache, dizziness, blurred vision or
IPRATROPIU obstructive airway History of nervousness; dryness aggravation of narrow-
M BROMIDE diseases in patients hypersensitivity to of mouth, throat angle glaucoma.
who require more soya lecithin or irritation; urinary • Can mix albuterol in
Brand than a single related food retention nebulizer for up to 1
name: bronchodilator products (for MDI hr.
Combivent only). • Ensure adequate
hydration, control
environmental
temperature to
prevent hyperpyrexia.
• Have patient void
before taking
medication to avoid
urinary retention.
• Teach patient proper
use of inhalator.
Brand Angiotensin II Treatment of Headache, upper • Check the doctor’s
name: 40mg/ Antagonists essential biliary obstructive resp tract infection, order before
Micardis tab hypertension. disorders, severe dizziness, fatigue. administering the
tablet OD hepatic medication.
impairment. • Follow the 10 rights
of medication
administration.
• Observe proper hand
hygiene in giving
medications.
• Instruct patient to
get help if
unnecessary condition
happens.
• Inform the patient
about certain side
effects.
• Instruct the patient
to inform the health
care provider if
 condition does not
improve or if feels
condition does not
change.

Brand Cholagogues, Acute and Chronic No known Abdominal pain, • Check the doctor’s
name: 1 cap Cholelitholytics Hepatitis: Dystrophy contraindication nausea, allergic order before
Essentiale bid & Hepatic and cirrhosis of the reaction administering the
Forte After Protectors liver, biliary stasis medication.
capsule BP and hepatic coma. • Follow the 10 rights
and of medication
after Liver Damaged by administration.
suppe Toxins: Fatty liver • Observe proper hand
r (eg, in diabetes, hygiene in giving
tuberculosis and medications.
chronic • Instruct patient to
rheumatism), get help if
prophylaxis of unnecessary condition
recurrent happens.
gallstones, radiation • Inform the patient
damage, nephrotic about certain side
syndrome and effects.
gestoses. • Instruct the patient
to inform the health
care provider if
condition does not
improve or if feels
condition does not
change.

Fenoflex Dyslipidaemic Severe renal Abdominal pain For dilution of

capsule 1 tab Agents Treatment of types dysfunction, back pain, solution for
3x a IIa, IIb, III, IV & V hepatic headache, intravenous
week hyperlipoproteinemi dysfunction eg flu syndrome; induction electrolyte
as. primary biliary abnormal liver
solutions should not
cirrhosis & function test,
unexplained diarrhea, be used.
persistent liver nausea, constipation;
function, increased ALT, CPK & • Follow the 10 rights
 preexisting AST; rhinitis. of medication
gallbladder administration.
disease. • Inform the patient
about certain side
effects.
•

Omepron Antacids, converted to active Symptomatic • Headache • Give before meals

capsule 20mg Antireflux metabolites that response to • Diarrhea • Do not crush or
cap 1 Agents & irreversibly bind omeprazole • Abdominal chew tablets, swallow
tabb Antiulcerants and inhibit H+-K+- therapy does not pain whole
after ATPase (an enzyme rule out the • Nausea • Evaluate for
BP on the surface of presence of a therapeutic response
• Dizziness like relief of
gastric parietal gastric
• Asthenia (loss Gastrointestinal
cells). It inhibits malignancy.
of strength) symptoms
transport of Atrophic gastritis
hydrogen ions into has been noted • Vomiting • Question if
the gastric lumen. occasionally in • Constipation Gastrointestinal
• Upper discomfort, nausea,
Omeprazole gastric corpus and diarrhea occurs.
increases the biopsies from respiratory
gastric pH and patients on long- tract infection
reduces gastric acid term omeprazole • Back pain
formation. therapy. • Rash

• Cough
Senokot 2 tab Laxatives, Functional Acute surgical Mild abdominal Assess baseline of
Tab 1tab Purgatives constipation of abdomen, discomfort; diarrhea elimination.
HS as hospitalized patient, abdominal pain, w/ excessive loss of
neces O & G patient, post- nausea, vomiting water & electrolytes Teach the patient how
sary surgical, prenatal, or symptoms of (high doses), to self administer
for postpartum, appendicitis; laxative.
consti geriatric patient, intestinal
pation functional hemorrhage or Encourage patient
constipation due to obstruction, normalize bowel
intake of certain persistent movement.
drugs, ped patient. diarrhea.

Avamys Nasal Treatment of nasal back pain, cough, • Check the doctor’s
nasal spray 2 Decongestants & ocular symptoms headache, minor Epistaxis, nasal order before
spray & Other Nasal of seasonal & nosebleed, nasal ulceration. administering the
each Preparations perennial allergic sore, or sore medication.
nostril rhinitis. throat. • Follow the 10 rights
OD of medication
administration.
• Observe proper hand
hygiene in giving
medications.
• Instruct patient to
get help if
unnecessary condition
happens.
• Inform the patient
about certain side
effects.
• Instruct the patient
to inform the health
care provider if
condition does not
improve or if feels
condition does not
change.

Montelukas Antiasthmatic Rash, angio-edema, Do not use this

t (kastair) 10mg & COPD Treatment of Do not use for pruritus & urticaria. medication if you are
OD Preparations bronchial asthma, treatment of acute Dizziness, headache, allergic to
allergic rhinitis asthma attacks. dream abnomalities, montelukast.
concomitant to hallucinations,
bronchial asthma & agitation including Before using
allergic rhinitis. aggressive behavior, montelukast, tell your
paresthesia/hypoesth doctor if you are
esia, drowsiness, allergic to any drugs
insomnia, irritability, (especially aspirin).
restlessness. You may need a dose
Somnolence, adjustment or special
dyspepsia, infectious tests to safely use this
gastroenteritis, medication.
diarrhea, nausea &
 vomiting. Nasal Take this medication
congestion, cough, exactly as it was
influenza, upper resp prescribed for you. Do
infection, increased not take the
serum alanine & medication in larger
aspartate amounts, or take it for
aminotransferase, longer than
pyuria. recommended by your
Asthenia/fatigue, doctor. Follow the
myalgia, fever, directions on your
trauma, dental & prescription label.
abdominal pain.
Bronchial asthma & Nausea, vomiting, •Use with caution in
Ansimar 400m Antiasthmatic pulmonary disease Acute MI, epigastric pain, patients with
g½ & COPD w/ spastic bronchial hypotension, cephalalgia, hypoxemia,
tab 2x Preparations component. irritability, insomnia, hyperthyroidism,
a day tachycardia, liver disease, renal
extrasystole, disease, in those
tachypnea, with history of peptic
ulcer and in elderly.
Frequently, patients
with CHF have
markedly prolonged
drug serum levels
following
discontinuation of
Ansimar.

• assess for allergic

reaction
assess for breath
sounds

•should be given to a
pregnant woman
only if clearly
needed.
Hydrocortis Corticosteroid Allergic states: Viral/fungal Muscle wasting, • Establish
one 100m Hormones / Eye Control of severe or infections, weakness, baseline and
g IV Corticosteroids incapacitating tubercular or osteoporosis. GI continuing data
q8 / Topical allergic conditions syphilitic lesions, disturbances and on BP, weight,
Corticosteroids intractable to bacterial infections bleeding. Increased fluid and
adequate trials of unless used in appetite and delayed electrolyte
conventional conjunction with wound healing. balance, and
treatment in appropriate Bruising, striae, blood glucose.
asthma, atopic chemotherapy. hirsutism, acne, • Lab tests:
dermatitis, contact flushing. Raised Periodic serum
dermatitis, drug intracranial pressure, electrolytes
hypersensitivity headache, blood glucose,
reactions, perennial depression, Hct and Hgb,
or seasonal allergic psychosis platelet count,
rhinitis, serum Hyperglycaemia, and WBC with
sickness, glycosuria, DM, differential.
transfusion obesity, moon-face, • Monitor for
reactions. buffalo hump. adverse effects.
Suppression of Older adults
pituitary- and patients
Gastrointestinal adrenocortical with low serum
diseases: To tide system. albumin are
the patient over a especially
critical period of the susceptible to
disease in regional adverse effects.
enteritis (systemic • Be alert to signs
therapy) and of hypocalcemia
ulcerative colitis. (see Appendix
F).
Hematologic • Ophthalmoscopi
disorders: c examinations
Acquired are
(autoimmune) recommended
hemolytic anemia, every 2–3 mo,
especially if
patient is
receiving
ophthalmic
steroid therapy.
• Monitor for
 persistent
backache or
chest pain;
compression
and
spontaneous
fractures of
long bones and
vertebrae
present
hazards.
• Monitor for and
report changes
in mood and
behavior,
emotional
instability, or
psychomotor
activity,
especially with
long-term
therapy.
• Be alert to
possibility of
masked
infection and
delayed healing
(antiinflammato
ry and
immunosuppres
sive actions).
• Note: Dose
adjustment may
be required if
patient is
subjected to
severe stress
(serious
infection,
 surgery, or
injury).
• Note: Single
doses of
corticosteroids
or use for a
short period
(<1 wk) do not
produce
withdrawal
symptoms
when
discontinued,
even with
moderately
large doses.

Floxel Treatment of adults Diarrhea, abdominal • Check the doctor’s

750m Quinolones ≥18 yr w/ mild, Hypersensitivity to discomfort, nausea, order before
g1 moderate & severe quinolones. IV anorexia, abdominal administering the
tab infections caused by Epilepsy, history of pain, vomiting, medication.
OD susceptible strains tendon disorders stomatitis & • Follow the 10 rights
of microorganisms related to heartburn; insomnia, of medication
in the following fluoroquinolone headache & administration.
conditions: therapy dizziness; rash, • Observe proper hand
Community- pruritus & eczema; hygiene in giving
acquired muscle & joint pain; medications.
pneumonia, acute bone marrow • Instruct patient to
bacterial depression. get help if
exacerbation of Increased liver unnecessary condition
chronic bronchitis, enzymes. Pain, happens.
reddening at the inj • Inform the patient
site, phlebitis. about certain side
effects.
• Instruct the patient
to inform the health
care provider if
condition does not
 improve or if feels
condition does not
change.

arcoxia Acute & chronic History of Immune System • Check the doctor’s
4mg Nonsteroidal treatment of the hypersensitivity to Disorders: order before
1 tab Anti- signs & symptoms etoricoxib or to any Hypersensitivity administering the
OD inflammatory osteoarthritis & RA. of the excipients of reactions including medication.
Drugs Treatment of Arcoxia. anaphylactic/anaphyl • Follow the 10 rights
ankylosing actoid reactions. of medication
spondylitis. Active peptic administration.
Treatment of acute ulceration or active Psychiatric Disorders: • Observe proper hand
gouty arthritis & GI bleeding. Anxiety, insomnia, hygiene in giving
primary confusion, medications.
dysmenorrhea. Patients who have hallucinations. • Instruct patient to
Relief of acute & experienced get help if
chronic pain. bronchospasm, Nervous System unnecessary condition
acute rhinitis, Disorders: Dysgeusia. happens.
nasal polyps, • Inform the patient
angioneurotic Cardiac Disorders: about certain side
edema, urticaria or Congestive heart effects.
allergic-type failure. • Instruct the patient
reactions after to inform the health
taking Vascular Disorders: care provider if
acetylsalicylic acid Hypertensive crisis. condition does not
or NSAIDs improve or if feels
including condition does not
cyclooxygenase-2 Respiratory, Thoracic
change.
(COX-2) inhibitors. and Mediastinal
Disorders:
Bronchospasm.
Established
ischemic heart
disease, peripheral Gastrointestinal
arterial disease Disorders: Abdominal
and/or pain, oral ulcers,
cerebrovascular peptic ulcers
disease. including perforation
and bleeding (mainly
in the elderly),
vomiting, pruritus,
rash, urticaria,
diarrhea.

Hepatobiliary
Disorders: Hepatitis:

Skin and
Subcutaneous Tissue
Disorders:
Angioedema, rash,
pruritus, Stevens-
Johnson syndrome,
urticaria.

Renal and Urinary

Disorders: Renal
insufficiency
including renal
failure, usually
reversible upon
discontinuation of
therapy (see
Precautions)