International College Page 1 of 5

Middle School
BIOLOGY TEST
Name: _________________ May 17, 2010
Class 4th ___________ Time: 50 minutes
Self assessment: /100

I. Completion: Complete each sentence or statement. (20%)

1. As a cell’s size increases, it places more demands on its_______________________

2. The __________________ a cell is, the more difficult it is for the cell to move enough materials
across its cell membrane.

3. Cell division solves the problem of cell growth by increasing cell ____________________ and
decreasing cell ___________________

4. Most of a cell’s growth takes place during the _____________________ phase of the cell cycle.

5. A cell’s chromosomes are duplicated during ____________________

6. If it takes a cell one hour to undergo mitosis, about 50 minutes of the time would be spent in
________________________

7. A cell splits into two daughter cells during _________________________

8. Proteins called ______________________ help regulate the cell cycle.

9. Lack of control over ____________________ is the cause of all cancers.

10. A cell that has 46 chromosomes in the G1 phase will have ____________________ chromatids
in metaphase.

II. Multiple Choice: Identify the letter of the choice that best completes the statement or answers
the question. (20%)
1. The speed with which wastes are produced by a cell depends on the cell’s
a. ratio of surface area to volume b. environment
c. volume d. surface area

2. Which of the following is a way that cell division solves the problems of cell growth?
a. Cell division provides each daughter cell with its own copy of DNA.
b. Cell division increases the mass of the original cell.
c. Cell division decreases the surface area of the original cell.
d. Cell division increases the original cell’s volume.

3. Which of the following is a correct statement about the events of the cell cycle?
a. Little happens during the G1 and G2 phases.
b. Cell plate forms during cytokinesis.
c. The M phase is usually the longest phase.
d. Interphase is usually the shortest phase.
 International College Page 2 of 5
Middle School
4. The cell cycle is the
a. series of events that cells go through as they grow and divide.
b. period of time between the birth and the death of a cell.
c. time from prophase until cytokinesis.
d. time it takes for one cell to undergo mitosis.

5. The first phase of mitosis is called

a. prophase b. anaphase c. interphase d. cytokinesis

6. During normal mitotic cell division, a parent cell having four chromosomes will produce two
daughter cells, each containing __________ chromosomes
a. two b. four c. eight d. sixteen

7. What happens when cells come into contact with other cells?
a. they divide more quickly b. they stop growing
c. they produce cyclins d. they produce p53

8. Cells grown in a petri dish tend to divide until they form a thin layer covering the bottom of the
dish. If cells are removed from the middle of the dish, the cells bordering the open space will begin
dividing until they have filled the empty space. What does this experiment show?
a. When cells come into contact with other cells, they stop growing.
b. The controls on cell growth and division can be turned on and off.
c. Cell division can be regulated by factors outside the cell.
d. all of the above

9. When cytoplasm from a cell that is undergoing mitosis is injected into a cell that is in interphase,
the second cell
a. stays in interphase b. enters mitosis
c. stops making cyclin d. loses its p53

10. Which of the following is an internal regulator of the cell cycle?

a. cyclins b. growth factors c. the mitotic spindle d. cancer cells

III. Answer the following questions

1. Relate ratio of surface area to volume to cell growth and cell division. (6%)
 International College Page 3 of 5
Middle School
2. List and describe only the main events of the cell cycle. Illustrate your description with a
concept map of the cell cycle. (12%)

3. Discuss the relationship between mitosis and cytokinesis. What would be the result if one
happened without the other? (6%)
 International College Page 4 of 5
Middle School
IV. The following diagrams represent different stages of cell division

a. Label structures 1, 2 and 3 (3%)

b. Place the above phases in the correct order (1%)

c. Give a title to each diagram and justify your answer. (9%)

d. Name the phases that are not represented in the above diagram. Draw labeled diagram(s) to
represent the missing phase(s). (6%)

e. When cell division ends, how many chromosomes will be present in each new nucleus? Explain
your answer.(4%)

f. How do you know if this is an animal cell or a plant cell?(2%)

 International College Page 5 of 5
Middle School
V. USING SCIENCE SKILLS

Figure 10-6

a. Interpreting Graphics Look at Figure 10-6. Which diagram shows cancer cells? How do you
know? (3%)

b. Predicting Look at the cancer cells shown in Figure 10-6. What can happen if these cells are left
untreated? (3%)

c. Describe how cancer cells are different from other cells. Based on these differences, explain why
cancer has been such a difficult condition to cure.(5%)