DRUG STUDY

ASSESSMENT

CLASSIFICATION

Generic Name: Acetylcysteine Brand Name: Mucomyst

Pharmacologic: Amino acid (L cysteine) derivative Therapeutic: Mucolytic, antidote for acetaminophen overdose

ACTION Increase respiratory tract fluid to help liquefy tenacious secretions. Restores glutathione in liver to treat acetaminophen toxicity

DOSAGE

NURSING CONSIDERATION Assess patients respiratory secretions before and often during therapy. Be alert for adverse reactions and drug interactions. drug is incompatible with tetracyclines, erythromycin lactobionate, amphotericin B and ampicillin sodium. Have suction equipment available in case patient cant effectively clear air passages. Alert prescriber is respiratory secretions thickens or become purulent or if bronchospasm occur. Activated charcoal may limit acetylcyteines effectiveness. Avoid use together.

EVALUATION Patient has clear lung sounds, decrease respiratory secretions, reduced frequency and severity of cough. patient and family state understanding of drug therapy.

600mg 1 tab in 200 ml of water, OD

ASSESSMENT Generic Name: Ampicillin sodium and sulbactam sodium (Ampi-sulbactam) Brand Name: Unasyn

CLASSIFICATION

ACTION Ampicillin inhibits cell wall synthesis during microorganism multiplication. Sulbactam inactivates bacterial beta-lactamase the enzymes that inactivates ampicillin and provides bacterial resistance to it.

DOSAGE 105 g TIV as loading dose 1 hour prior then 750 mg TIV q6h, (-) ANST

NURSING CONSIDERATION Obtain history of patients infection before therapy and observe throughout therapy to determine improvement. Ask patient about previous allergic reactions to penicillin. Obtain specimen for culture and sensitivity. Be alert for adverse reaction and drug interaction May increase BUN, creatinine, AST, ALT, Alkaline phosphatase, bilirubin, LDH, CK and GGT level. May decrease Hgb and Hct level. Probenecid increases ampicillin level. Tell patient to call prescriber if rash, fever or chills develop. If adverse GI reaction occurs, monitor patients hydration. Monitor liver function test

EVALUATION Patient is free from infection. Patient and family state understanding of drug therapy. Patient decreased the multiplication of bacteria or lessen the production of bacteria

Pharmacologic: Aminopenicillin and beta lactamase inhibitor. Therapeutic: Antibiotic

result during therapy, especially in patients with impaired liver function.

ASSESSMENT Generic Name: Metoprolol

CLASSIFICATION

ACTION Known to depress rennin secretion. Reduces Bp, decreases

DOSAGE 50 mg, I tab BID

NURSING CONSIDERATION Assess patients condition before starting therapy and regularly thereafter to monitor drug effectiveness.

EVALUATION Patient responds well to therapy. Patient does not experience injury from

Pharmacologic: Selective beta1 bloker

Brand Name: Neobloc

Thereapeutic: antihypertensive, adjunct therapy of acute MI.

myocardial contractility, HR and cardiac output

Monitor blood pressure often. Always monitor apical pulse rate before giving. Below 60 beats/ min. do not give drug and call the prescriber. If P.O give drug with meals because food may increase absorption. Be alert for adverse reaction and drug interactions. Instruct patient to report these reactions. Warn patient to avoid performing hazardous activities until drugs CNS effects are known.

adverse CNs reactions. Patient and family state understanding of drug therapy.

ASSESSMENT

CLASSIFICATION

ACTION

DOSAGE

NURSING CONSIDERATION

EVALUATION

Generic Name: Atorvastatin sodium Brand Name: lipitor

Pharmacologic: HMG-COA reductase inhibitor Therapeutic: Anti-lipemic

Selectively inhibits HMGCoA reductase which converts HMG-CoA to mevalonate- a precursor of sterols. Lowers cholesterol and lipoprotein levels.

80 mg, 1 tab. OD/Hs

Monitor patients lipid and Patients cholesterol liver function levels at level is within normal baseline and periodically levels. thereafter. Drug can be given as a single dose with or without food. Teach patient about proper diet, weight control and explain their role in controlling lipid levels. Tell patient to inform prescriber of adverse reactions such as muscle pain, tenderness, or weakness esp. if patient accompanied by fever or malaise. May increase digoxin level. Monitor level. Warfarin may increase anti-coagulant effect. Antacids may decrease bio-availability.

http://general-medicine.jwatch.org/cgi/content/full/2011/505/3

http://general-medicine.jwatch.org/cgi/content/full/2011/621/2