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S1253 Lacosamide
Technical Data:
M.Wt: Formula: Solubility: Purity: Storage: CAS No.: 250.29 C13H18N2O3 DMSO 99% at -20 2 years 175481-36-4
HN O HN O
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Synonyms: Erlosamide,
Vimpat
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techbio@selleckchem.com
(bio support)
Biological Activity
Lacosamide is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.[1] Lacosamide is a functionalized amino acid that has activity in the maximal electroshock seizure test, like antiepileptic drugs that are believed to act through voltage-gated sodium channels. However, lacosamide does not act in a conventional way to stabilize fast sodium channel inactivation. Rather, it enhances slow inactivation.[1] Lacosamide does not affect AMPA, kainate, NMDA, GABAA, GABAB or a variety of dopaminergic, serotonergic, adrenergic, muscarinic or cannabinoid receptors and does not block potassium or calcium currents. [1]
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References
[1] http://en.wikipedia.org/wiki/Lacosamide [2] http://www.rxlist.com/vimpat-drug.htm
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Notes
PLEASE KEEP THE PRODUCT UNDER -20 FOR LONG-TERM STORAGE. NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products, stored under the recommended conditions, are stable for two years. Products are sometimes shipped at a temperature that differs from the recommended storage temperature,most are recommended stored at -20 Many products are stable in the short-term at temperatures that differ from that . required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save your shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage recommendations on the product data sheet.
be received from our customer service team. Returns accepted will be subject to a 30% restocking charge.
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