Professional Documents
Culture Documents
The exact sequence of amino acids comprising the insulin molecule, the
so-called primary structure, was determined by British molecular biologist
Frederick Sanger. It was the first protein the structure of which was
completely determined. For this he was awarded the Nobel Prize in
Chemistry in 1958. In 1967, after decades of work, Dorothy Crowfoot
Hodgkin determined the spatial conformation of the molecule, by means
of X-ray diffraction studies. She also was awarded a Nobel Prize.
INSULIN 3D structure
Link: www.3dchem.com/molecules.asp?ID=196 - 9k
HISTORY of Insulin
Insulin
Insulin is a hormone produced in the pancreas. It was isolated in 1921-22
at the University of Toronto. The scientists involved in the research were
Dr. Fredrick Banting, Charles Best (a medical student at the time of the
discovery), Professor J. J. R. Macleod and Dr. James Collip. On June 3,
1934, Dr Frederick Banting the co-inventor of insulin was knighted for his
medical discovery.
Insulin Process
Discovery of Insulin
Brief biographies of the scientists (Banting, Best, Macleod and Collip)
surrounding the discovery of insulin and treatments for diabetes. It
provides descriptions of their experiments via a scrapbook of old
newspaper clippings, pictures, and a voice recording. There is a list of
books,videos, and links available on the subject of diabetes.
Insulin Process
Banting, Macleod, Best and Collip invented the process for insulin in 1922
which became the treatment for diabetes.
A Great Canadian Breakthrough: The Discovery of Insulin
Helen Free and the Home Diabetes Test
Helen Free
Helen Free invented the home diabetes test.
Helen Free
In the mid-1940s, Alfred Free and Helen Murray were both chemists
working together in the biochemistry research group at Miles
Laboratories, Inc. Married in 1947, they continued their collaboration,
becoming two of the world’s leading experts on urinalysis the highlight of
which was Helen Free's invention of the home diabetes test.