Slides: 司遠征博士-記憶力與神經系統的保健

健康讲座
脑与神经系统的保健
司远征， M.D. Ph.D.
Saturday, October 18, 2008 1

Our Brain

READ HEAR
H
E
THINK SPEAK

•Brainwave research on cognitive performance has pointed to the mid Beta brainwave
frequencies as the zone to create a super focus mental state, intellectual endurance, and
optimize your brain to handle intensive task with high levels of mental stamina.

中风所损及的脑组织
1. 大脑左半球 2. 大脑右半球
3. 脑干 4. 小脑

Alzheimer’s and Dementia
• Mild Cognitive Impairment (MCI)
• Vascular Dementia
• Mixed Dementia
• Dementia with Lewy Bodies
• Alzheimer’s Disease
• Parkinson's Disease
• Frontotemporal Dementia
• Creutzfeldt-Jakob Disease (CJD)
• Normal Pressure Hydrocephalus
• Huntington's Disease
• Wernicke-Korsakoff Syndrome

Healthy BrainAlzheimer’s Brain

Potential Targets for
Intervention in AD

Alzheimer's Disease Risk Factors
Diabetes Mellitus
Cholesterol and Cholesterol-Lowering
Agents
Inflammation and NSAIDs
Cardiovascular Conditions and Risk
Factors
Other Lifestyle Factors
Heritage
Social and Psychological Factors
By Martha Clare Morris, ScD, Med Scope Toda

Stages of Alzheimer's
• Stage 1: No impairment
• Stage 2: Very mild decline
• Stage 3: Mild decline
• Stage 4: Moderate decline (mild or early
stage)
• Stage 5: Moderately severe decline
(moderate or mid-stage)
• Stage 6: Severe decline (moderately
severe or mid-stage)
• Stage 7: Very severe decline (severe or
late stage)
The difference between Alzheimer's
and normal age-related
memory changes
Someone with Alzheimer's Someone with normal age-
disease symptoms related memory changes
Forgets entire experiences Forgets part of an experience
Rarely remembers later Often remembers later
Is gradually unable to follow Is usually able to follow
written/spoken directions written/spoken directions
Is gradually unable to use notes as Is usually able to use notes as
reminders reminders
Is gradually unable to care for self Is usually able to care for self
Vitamin B Deficiency and
AD
• Elevated homocysteine and low folate
were associated with radiological markers
of neuropathology. Since no patient had
clinically deficient folate, it may be
important to rethink what defines
functionally significant micronutrient
deficiency and explore what this means in
different age- and health-status groups.
• Am J Geriatr Psychiatry. 2004 Nov-Dec;12(6):631-

8
Candidate strategies for
primary prevention of AD
By Peter Zandi and John Breitner,
Dept. Mental Hygiene, Johns Hopkins University, Baltimore, USA
• Non-steroidal anti-inflammatory
drugs
• Hormone replacement therapy
• Antioxidants & vitamins
• Statins and histamine H2
blockers
Nutritional Supplements for Brain and
Mental Health
• OPC-3
• Vita-Mind
• Oxygen Plus
• Cognitin
• Vit B Complex
• Omega III Fish Oil with Vitamine E
• Coenzyme Q10
• ResVeratrol
• Isotonic Acai
• Calcium Plus
• Headrest
• Bliss Anti-Stress Formula
Antioxidant
OPC-3 TM
10/18/08 22
23
Saturday, October 18, 2008
“ One of the principal ingredients
that makes Market America’s
Isotonix® OPC-3™ probably
the best antioxidant cocktail
in the marketplace is
Pycnogenol.”
Dr. Steven Lamm

New York University Professor
Bellevue Hospital

Isotonix OPC-3
• Potent antioxidants that neutralize oxygen

free radicals and regenerate the
antioxidant potency of vitamin C and
vitamin E
• Reduces cell damage which allows for
improved cellular metabolism and
function
• Improve circulation, especially capillary
• Helps boost immune system and decrease
inflammation

Vita-Mind
• Contains vitamins, minerals, nutrients and
natural herbs.
• Increase the amount of blood and oxygen to the
brain.
• Fortifying the brain against stress.
• Protecting it against the ravages of free radical
damage.
• Heightening electrical activity so that vital
neurotransmitters can operate efficiently.
• Enhance mental resistance to stress, mental
clarity, alertness and improve working and long-
term memory

Oxygen Plus
抗氧化长青素

28
Oxygen Plus
• Contains a wide array of antioxidants
which are effective against 7 forms of free
radicals
• Most complete antioxidant formulation
available
• Complements the Isotonix program of
OPC-3, Antioxidant, Vitamin C &
Isochrome/CoQ10
• Improve circulation and oxygen delivery
(Ginko, Glutathion)
• Enhance the alert of brain (Green tea)
Oxygen Plus
Ingredients ：
• 抗氧化维生素和微量元素组合，
A 、 E 满足日推荐量， C 为推荐量
的三倍，硒也接近推荐量的三倍。
• 多种天然植物提取物：高剂量的绿
茶提取物、银杏叶提取物、奶蓟提
取物、覆盆子粉末。
October 18, 2008 30

Cognitin™ Memory
Support Formula
A
c
e
t
y
l
Product Code: 13095
31
Type of Free Radicals
• Superoxide anion
( 過氧化陰離子 , O-2 和 O-2 含的鹽類
)
• Hydroxyl radical ( 羻基﹑ 氫氧基 ,
OH- )
• Hypochlorous acid ( 次氯酸 , ClO- )
• Nitric oxide ( 硝基 , NO- )
• Singlet oxygen ( 单一氧原子 O- )
• Hydrogen peroxide ( 过氧化氢 , H2O2)
10/18/08
• Fatty acid hydroperoxides 32
Cognitin™ Memory
Support Formula
• Acetyl-L-carnitine: Helps promote enhanced
memory and cognitive function. It is able to travel
through the blood-brain barrier where it helps form
the brain chemical acetylcholine.
• Alpha-lipoic acid: Both water and fat soluble and
can regenerate antioxidants, such as vitamin E,
vitamin C and glutathione.
• Vinpocetine: Supports healthy brain energy and
blood supply. It has been noted to support oxygen
and glucose utilization by brain cells and help
maintain their resistance to damage by hypoxia, or
lack of oxygen to the brain.
•

Isotonix Advanced B
Complex
• This product contains Vitamines B12, B2, B6,
Folic Acid and Magnesium.
• Vitamin B12 is essential for the normal
functioning of all body cells, but especially
those of the nervous system, bone marrow,
and intestinal tract. Both folic acid and vitamin
B12 are involved in the normal development
and functioning of the red blood cells and
they work in conjunction to construct the
genetic material of the cells. Vitamin B12 is
important for the metabolism of carbohydrate
and lipids. Folic acid is also responsible for
normal utilization of amino acids and proteins.
Vit B Complex
• Necessary for the synthesis of red blood
cells.
• Important in maintaining the nervous system.
• Plays a vital role in the metabolism of fatty
acids essential for the maintenance of
myelin.
• Prolonged B12 deficiency can lead to nerve
degeneration and irreversible neurological
damage.

Advanced Vit B Complex
• Promotes normal cognitive performance
• Increases energy
• Deficiencies in folic acid, vitamin B12, vitamin B6
or biotin may result in feelings of fatigue
• Promotes healthy levels of homocysteine
and supports normal endothelial function
• Promotes cardiovascular health
• Helps decrease stress and improve mood
• Helps maintain healthy levels of serotonin
• B Vitamins are essential for many key functions in
the body

Dendrite
Axon Terminal
Node of
Ranvier
Soma
Axon Schwann cell
Myelin sheath
Nucleus

人
體
內
秘密
殺
手
Essential Omega III Fish Oil
with Vitamin E
• Each daily serving provides 6000 mg of fish oil to
supply 1800 mg of EPA and 1200 mg DHA
• Promotes overall cardiovascular health
• Helps maintain healthy levels of C-reactive
protein
• Helps maintain normal triglyceride levels in the
blood
• Helps maintain normal blood flow
• Promotes healthy blood pressure levels
• Helps maintain normal cholesterol levels
• Helps enhance mood
•Saturday,
Promotes a healthy complexion
October 18, 2008 41
Essential Omega III Fish Oil
with Vitamin E
• Each daily serving provides 6000 mg of fish oil to
supply 1800 mg of EPA and 1200 mg DHA
• Promotes overall cardiovascular health
• Helps maintain healthy levels of C-reactive
protein
• Helps maintain normal triglyceride levels in the
blood
• Helps maintain normal blood flow
• Promotes healthy blood pressure levels
• Helps maintain normal cholesterol levels
• Helps enhance mood
•Saturday,
Promotes a healthy complexion
October 18, 2008 42
Coenzyme Q10 In The Mitochondrion
Cristae
Intermembrane space
Matrix
Outer Membrane
Inner Membrane

CoQ10 研究结果
• “ … This has implications for therapeutic

applications in human diseases, and there is
evidence for its beneficial effect in
cardiovascular and neurodegenerative
diseases. CoQ10 has an excellent safety
record.”
• Bhagavan, Hemmi N., Chopra, Raj K. : Coenzyme Q10:
Absorption, tissue uptake, metabolism and
pharmacokinetics, Free Radical Research, Volume
40, Number 5, May 2006, pp. 445-453(9)
46
Coenzyme Q10
• Concentrated in high energy tissues:
heart,
lung, brain, kidneys, spleen and
muscles
• Mainly locate in mitochondria (energy
• producing powerhouse) of cells.
• 2 Vital roles:
• Potent antioxidant
Isotonix® Resveratrol
The new Isotonix Resveratrol*:
•Promotes apoptosis (programmed cell death) in
unhealthy cells
•Helps maintain cell health
•Promotes cardiovascular health (promotes normal
platelet activity, helps maintain normal
vasorelaxation, provides antioxidant protection of
LDL particles)
•Promotes normal activity of the SIRT-1 gene
Single Bottle
(involved in calorie restriction, fat mobilization, (30 Servings)
mitochondrial function) Code: 13061
•Promotes normal cell cycle traverse DC: $32.00;
•Promotes normal nuclear factor kappa B (NF- SR: $44.95;
Kappa B — protein) and cyclooxygenase-2 (COX-2 BV: 27.00
— enzyme) activity
•Superior antioxidant and high ORAC value

Resveratrol
Fresh grape skin contains about 50 to 100 micrograms of resveratrol per gram

Red Wine Extract Prevents
Neuronal Apoptosis in Vitro
and Reduces Mortality of
Transgenic Mice .
Rosalaba Amodio et al
Annals of the New York Academy of
Sciences.
November 2006 , Vol. 1089: 88-97

Isotonix Acai
October 18, 2008 54

Primary Benefits
• Increases energy
• Provides strong antioxidant protection
• Supports normal cell cycle and cell integrity
• Helps maintain cardiovascular health
• Helps maintain healthy cholesterol levels
• Supports immune functions
• Promotes cognitive health
• Helps improve mental focus
• Helps improve memory
• Promotes healthy blood sugar levels
• Supports weight control
• Promotes prostate health
• Promotes normal regulation of enzymes and
hormones
•
Calcium Plus
(FDA Supported)
• Provides the body with an advanced, cost-

effective and generous 700 mg dose of needed
calcium through an optimized blend of calcium,
vitamin D3, magnesium, vitamin C, and boron.
• Vitamin D3 helps to get calcium across cell
membranes and store the mineral inside the cells.
• Plays a critical role in the building and
maintaining of strong bones.
• plays a major role in blood clotting, the
contraction of skeletal and heart muscles
• Support an effort to prevent osteoporosis.
56
Calcium Plus
• Contains 5 kinds of calcium and Vit

D3 and other vitamins and minerals
• Adjust the electrical activity of nerve
cells in our bodies.
• Initiates the changes in sodium and
potassium conductance .
• helps to calm down the nerve system
and promote sleeping.

Awake - Caffeine Free Energy Drinks
Product Code: 13182

HeadRest
• Helps maintain optimal blood flow to the brain
• Helps the body maintain a healthy (or sufficient or
proper) level of magnesium, which correlates with
brain health
• Helps to maintain brain health
• In clinical trials in both Germany and the United
States, butterbur reduced the incidence of head
cavity discomforts by up to 61 percent
• Magnesium deficiency is common among head
discomfort sufferers
• Promotes normal sinus function
• Promotes proper blood circulation in the brain which
helps to maintain head comfort (or which works to
support head comfort)
• Supports/promotes head comfort (reduces the
frequency, severity, and duration of head
discomfort)
• Supports/Promotes healthy cognitive function
• Supports/promotes healthy platelet activity and
blood vessel dilation (inhibits serotonin release from
59
platelets and leucocytes)
Depression
Bliss: How does it work?
• Bliss is comprised of several stress-
reducing herbs. These herbs work
together to help reduce overall stress
Primary Benefits
• Helps body adapt to stress
• Promotes relaxation without
drowsiness
• Maintains healthy levels of both
serotonin and dopamine
• Helps
Saturday, enhance
October 18, 2008 and stabilize mood 61
THE END
THANK YOU

Slides: 司遠征博士-記憶力與神經系統的保健

Uploaded by

Document Information

Original Description:

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Slides: 司遠征博士-記憶力與神經系統的保健

Uploaded by

Copyright:

Available Formats

健 康讲 座

Saturday, October 18, 2008 1

Saturday, October 18, 2008 2

Saturday, October 18, 2008 5

Saturday, October 18, 2008 7

Saturday, October 18, 2008 8

Saturday, October 18, 2008 10

Saturday, October 18, 2008 11

Saturday, October 18, 2008 13

Saturday, October 18, 2008 14

• Am J Geriatr Psychiatry. 2004 Nov-Dec;12(6):631-

Dr. Steven Lamm

Saturday, October 18, 2008 24

• Potent antioxidants that neutralize oxygen

Saturday, October 18, 2008 25

Saturday, October 18, 2008 26

Saturday, October 18, 2008 28

October 18, 2008 30

Saturday, October 18, 2008 33

Saturday, October 18, 2008 35

Saturday, October 18, 2008 36

Axon Schwann cell

Saturday, October 18, 2008 37

Saturday, October 18, 2008 45

• “ … This has implications for therapeutic

Saturday, October 18, 2008 48

Saturday, October 18, 2008 49

Saturday, October 18, 2008 50

October 18, 2008 54

• Provides the body with an advanced, cost-

• Contains 5 kinds of calcium and Vit

Saturday, October 18, 2008 57

Product Code: 13182

Saturday, October 18, 2008 58

Saturday, October 18, 2008 62

You might also like

健康讲座