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PA8MA vlSlCn lC8 CA1 2012 nlL8
!LL 2012

Vision : We are gland to present compressive study Material Ior All india level
Pharma entrance examination as per new patten.


Pharma Vision Provides 2 Iacilities which help you throughout your study Ior All
india level Pharma entrance examination .

We are launching a GPAT Study material according to new
syllabus and it is our gurantee that iI you will read our material oI
only 800 pages which is divided in Iour modules surely it will give
success in GPAT-2012.
The study material was prepared by NIPER , Mohali & M.S.
University students.
or Your satisIaction some portion oI a Module will be provided
as Iree sample.
Then as per your choice you can buy the material.
The cost oI this GPAT study material package is Rs.1500/-
NIPER Study Materials is 800/- .
MCQ Bank is 800/-.

1. GPAT Study Material

The content oI study material is Iollows:

1.Module -I-Pharmaceutics

2.Module-II-Pharmaceutical Chemistry

3. Module-III-Pharmacognosy

4. Module-IV-Pharmacology


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. NIPER's Previous Year paper & study material

6.List of important books related to GPAT

8. CD containing Soft copy of Books ( 3 books of Each Module)



2. MCQ's BANK :


harmavlslon ls very proud Lo announce a mulLlple cholce quesLlonnalrea book
unllke oLhers provldes modules speclflc chapLer wlse quesLlons MCC Culdes
conLalns slngle llne AsserLlon 8easonlng and SLaLemenLs Lype MCC as per new
paLLen


GPAT & NPER JEE Model Papers

O 20 section wise GPAT Model Papers
O 10 pre GPAT Model Papers
O 10 pre NPER JEE Model Papers


Get free updates for GPAT & NPER JEE.
Type "ON PHARMAVSONGPAT send to 9870807070.

Contact 09427360746
E-Mail : pharmavisiongpat@gmail.com







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S|ze separat|on
arLlcle Slze sepraLlon by dlfferenL meLhod
Slze sepraLlon meLhod arLlcle dlameLer (mlcron)
Slevlng 310000
SedlmenLaLlon
(a) CravlLaLlonal
(b) CenLrlfugal

31000
013
LluLrlLlon
(a) WaLer and Alr gravlLaLlonal
(b) CenLrlfugal

10300
0330
Cyclone separaLlon 230

SLandards of powder
Crade of powder Sleve Lhrough whlch all parLlcle
musL pass
Sleve Lhrough 40
parLlcle pass
Coarse 10 44
ModeraLely coarse 22 60
ModeraLely flne 44 83
llne 83 120
very flne 120
Mlcroflne 330 (90 pass)
Superflne 90pass Lhrough 10 mlcron


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1ypes of 8|nders
1A8LL CLASSlllCA1lCn Cl 8lnuL8S
SUGAkS NA1UkAL 8INDLkS SN1nL1IC]SLMISN1nL1IC CLMLk
Sucrose Acacla MeLhyl Cellulose
Llquld glucose 1ragacanLh LLhyl Cellulose
CelaLln Pydroxy ropyl MeLhyl Cellulose (
PMC)
SLarch asLe Pydroxy ropyl Cellulose
regelaLlnlzed SLarch Sodlum Carboxy MeLhyl Cellulose
Alglnlc Acld olyvlnyl yrrolldone (v)
Cellulose olyeLhylene Clycol (LC)
olyvlnyl Alcohols
olymeLhacrylaLes

1A8LL CCMMCnL? uSLu 8lnuL8S
8INDLk CA1LGCk MANUIAC1UkLk
SLarch 1300
arLlally regelaLlnlzed Malze SLarc
h
Colorcon
MeLhocel Pydroxy ropyl MeLhyl Cellulose uow Chemlcals
Walocel Pydroxy ropyl MeLhyl Cellulose
WolffCelluloslcs
naLural SLarch and Chemlcal Compan
y
LuvlLec olyvlnylpyrrolldone 8ASl Company
Luvlcross olyvlnylpyrrolldone 8ASl Company
LuvlcaprolacLa
m
olyvlnylcaprolacLam 8ASl Company




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3.Lipids
Saponification value
Saponification is the base-catalyzed hydrolysis of an ester. mgs of KOH required to
saponify 1 g of fat.
!roducts of the reaction are- An alcohol and An ionized salt which is a soap
cid Value

umber of mgs of KOH required to neutralize the Free Fatty Acids in 1 g of fat, that
number indicate degree of rancidity

Iodine Value
umber of iodine (g) absorbed by 100 g of oil.
olecular weight and iodine number can calculate the number of double bonds. 1 g
of fat adsorbed 1.5 g of iodine value = 150.
#ancidity
ue to long exposure to air, a foul odour or smell comes known as rancidity.

%riglyceride Fatty acids


Specially C
4
butyric acid and other short chain fatty acids in butter are the real
problem.
atty cids No. of Carbons (Double bonds)
!almitic acid 16(0)
Stearic Acid 18(0)
Oleic acid 18(1)
yristic acid 14(0)
Linoleic acid 18(2)
Linolenic acid 18(3)
Arachidonic acid 20(4)
Lauric Acid 12(0)
Capric Acid 10(0)




CxldaLlon (Alr MolsLureLlghL)
Llpase

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1ypes of Dens|ty
1rue uenslLy Pellum pycnomeLer (orous solld)
Llquld dlsplacemenL (non orous solld)

M/v
L
Cranule uenslLy Mercury dlsplacemenL meLhod


M/v
g

8ulk uenslLy CraduaLed cyllnder meLhod based on
1applng Lhe powder from l1 lnch helghL
1hrlcely ln 2 mln lnLerval

M/v
b



CAkk's INDLk
CompresslblllLy llow
313
1216
1821
2328
2833
3338
40
LxcellenL
Cood
lalr
oor
oor
very poor
LxLremely poor


nAUSNLk kat|o
PAuSnL8 8aLlo

1ype of llow
Less Lhen 123
123 13
More Lhen 13
Cood flow
ModeraLe
oor llow



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ANGLL CI kLCSL
AnCLL Cl 8LCSL

1ype of llow
23
23 30
3040
40
LxcellenL
Cood
assable
oor llow




















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nAkMACLU1ICAL CALCULA1ICNS

Ca|cu|at|ons of Doses for Ch||dren

1he followlng are used for calculaLlon of doses for chlldren

1 oung Iormu|a Age (?ears) x AdulL uose uose of Lhe Chlld
________

Age+ 12

2 D||||ng's Iormu|a Age (years) x AdulL dose uose of Lhe chlld
_________
20

3 Cow||ng's Iormu|a Age (years) x AdulL dose uose of Lhe chlld
_________
24

4 Ir|ed's formu|a Age ( MonLhs) x AdulL dose r uose of Lhe chlld
__________
130

3 C|arke's formu|a



6 8astedo's formu|a Age (years) + 3 x AdulL dose uose of chlld
__________
30

7 Ca|cu|at|on based on body surface area



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usually Lhe body surface area of an adulL ls Laken as 173 sq m



ALkALCID


1rue a|ka|o|ds conLaln heterocyc||c N|trogen wh|ch |s der|ved from am|no ac|d and always
baslc ln naLure due Lo presence of lone palr of elecLrons on nlLrogen

roto a|ka|o|ds are slmple amlnes ln whlch N|trogen |s not heterocyc||c Lg ephedrlne
Colchlclne mescallne


seudo a|ka|o|ds Lhey are not der|ved from am|no ac|ds buL Lhey show poslLlve LesL for
alkalolds Lg purlnes

(caffelne) sLeroldal and Lerpenoldal alkalolds Conesslne solanldlne proLoveraLrlne aconlne


Vo|at||e a|ka|o|ds conllne nlcoLlne sparLelne


Co|ored a|ka|o|ds 8erberlne (yellow) 8eLanldln (8ed)


- Some of proLo and pseudo alkalolds show hlgher solublllLy ln waLer eg Colchlclne
caffelne qulnlne PCl are freely soluble ln waLer So solublllLy of alkalold ls also
employed for exLracLlon procedures

Alkalolds wlLh rlmary amlne nlLrogen
Mescallne Alkalolds wlLh Secondary amlne
nlLrogen Lphedrlne Alkalolds wlLh
1erLlary amlne nlLrogen ALroplne
Alkalolds wlLh uaternary N|trogen


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1ubocurar|ne Chem|ca| test
| Mayer's reagent test (k
+
mercur|c |od|de so|ut|on) Cream co|ored
ppt
|| Dragendroff's reagent (k
+
b|smuth |od|de so|ut|on) ked brown
ppt ||| Wagner's
reagent (|od|ne k
+
|od|de so|ut|on ) ked brown
ppt
|v nager's reagent (|cr|c ac|d) e||ow
co|ored ppt v |cro|on|c ac|d e||ow
co|ored ppt

C|ass|f|cat|on


a yrrole and yrrolldlne rlng Pygrlne Cocoa

b yrldlne and plperldlne Conllne Arecollne Lobellne

c u|no||ne Camptothec|n (Ant|cancer) Culnlne Clnchonlne

d Isoqu|no||ne D1ubocuar|ne (Ske|eta| musc|e re|axant) Morph|ne
8erber|ne Lmet|ne e Indo|e LrgoL 8eserplne vlnca SLrychnlne
hysosLlgmlne
f Im|dazo|e llocarplne

g Culnazollne vasaka (anLlLusslve expecLoranL)

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