Case 7 NBSS Mood Disorder #dag dig dug dueeer gak berasa dah case 7 :D General Learning Objective

after completing the case, the students should be able to 1. Describe the term and definition of mood disorder 2. Describe classification of mood disorder 3. Describe epidemiology of mood disorder 4. explain the etiology of mood disorder 5. review the anatomy and physiology of limbic system 6. explain the neurotransmitter involved in mood disorder 7. explain the psychopathology and psychodinamic of mood 8. exlain the signand symptom of mood disorder 9. differential diagnosis of mood disorder 10 explain the management of mood disorder 11.explain the course and prognosis of mood disorder 12 describe the medicolegal aspects of mood disorder 13. describe the definition of personality 14. describe the classification of personality disorder 15. explain the sign and symptom (diagnostic feature) of dependent personality disorder 16. describe the epidemiology of dependentpersonality disorder 17.explain complication comorbidity and impairment of dependent personality disorder 18. explain epidemiology of dependent personality disorder 19. explain the etiology, psychodynamic of dependent personality disorder 20.Differential diagnosis of dependent personality disorder 21. explain the management of dependent personality disorder 22.expalin the course and prognosisof dependent personality disorder Learning Objective of Case 5 NBSS (Dementia) after completing the case, the student should be able to 1. explain the anatomy, histology and physiology of cerebral cortex 2. explain the concepts of cognition and memory and higher cortical cortex 3. differentiated normal age-associated, forgetfulness, mild cognitive impairment, dementia, delirium, and depression by comparing. 4. describe the definition and incidence of delirium 5. describe the etiology of delirium 6. describe the diagnostic criteria of delirium 7. describe the differential diagnosis of delirium 8. explain the principle of delirium management 9. descrlogicalibe of the course and prognosis of delirium 10. describe the definition, classification, etiology,and epidemiology of dementia. 11. describe the neurotransmitter involvement in memory process and cognition 12. describe the pathophisiology and neuropathology of dementia 13. describe the psychiatric and neurological changes of dementia. 14. describe the diagnostic criteria and tools for diagnosing dementia 15. describe the differential diagnosis of dementia 16. explain the principle management of dementia 17. explain of the course and prognosis of dementia 18. recognize the indication for dementia case referral 19. evaluate the medico-legal, BHP, PHOP, CRP aspect of the case. case 4 NBSS Parkinson Disease, LO : at the end of the course the student will be able to describe 1. Anatomy, physiology and neurotransmitter related to movement (basal ganglia and extrapyramidal system) 2. definition of parkinsonism and Parkinson disease 3. classification and etiology of parkinson 4. pathology and etiopathogenesis of PD 5.pathophisiology of PD

6. clinical feature and staging of PD 7. diagnosis and differential diagnosis f PD 8. Management of PD 9. Course and prognosisof PD 10 medico-legal aspect of PD case 3 : 1. anatomi, histologi, embriologi, fisiologi (cerebrum-dibahas fungsi2 lobus-, cerebellum, brainstem, meningeal layer) 2. CSF (sintesis, komposisi, aliran, fungsi) 3. Blood Brain Barier 4. fisiologi conciusnes (Reticular Activating System-fisiologis dan patologis, ascending-descending tract) 5. fisiologi CN I-XII ( pusat, jalur keluar foramen) 6. corticospinal-corticobulbar tract 7. vaskularisasi arteri carotid otak (circle of wilis) 8. sinus-sinus otak 9. stroke iskemik-haemorrhage 10. inervasi + veskularisasi meninges 11. komplikasi hypertensi 12. intracranial pressure 13. mekanisme hypertensi yang melibatkan pembuluh darah 14. stroke (klasifikasi, definisi, DD, mekanisme-patpat, sign symptom, prevention primer-sekunder, komplikasi, rehabilitasi, prognosis) 15. PP mannitol case 2 : 1. definisi cedera medulla spinalis dan prognosisnya 2. anatomi vertebra (bagian-bagian) 3. anatomi segmental spinal cord + fungsinya 4. anatomi secxial section spinal cord (cervical, thorac, lumbar, sacral) 5. mekanisme cedera + penyebabnya 6. gambaran klinis cedera medula spinalis (complete-incomplete) 7. ascending-descending tract 8. fungsi spinal cord (simpatik, parasimpatik) 9. fungsi sensorik-motorik pathway 10. lapisan spinal cord (meninges) 11. reflex arch 11. spinal cord disease (insidensi, PE, definisi, kalsifikasi, management, komplikasi, patogenesis, management, brown sequard syndrom, anterior/posterior cemtral cord syndrom, anteroquard syndrom. 12. histologi spinal cord 13. anxiety disorder (all about, di dalam klasifikasi dibahas PTSD) 14. perbedaan anxiety normal-abnormal 15. perbedaan anxiety dan fear 16. kriteria diagnosis PTSD 17. PTSD dan acute stress 18. PTSD (etiologi faktor, psikopatogenesis, psikopatologis, biological factor, management, treatment) case 1 1. anatomi saraf perifer 2. anatomi spinal cord (dorsal-ventral root ganglion) 3. inervasi otot2 ekstrimitas atas-bawah 4. histologi saraf perifer 5. neuromuscular junction 6. embriologi saraf perifer 7. potensial aksi saraf 8. pembentukan selubung myelin 9. klasifikasi serabut sraf (myelinated-unmyelinated) 10. topografi sensoric distribution (dermatome, sklerotome, myotome) 11. general concept of lower motor neuron (sensory, motoric, reflex) 12. patologis dan disorder polyneuropathy

13. 14. 15. 16. 17. 18.

hub infeksi neuropathy dengan degenarasi wallerian patomekanisme degenasi saraf perifer, degenasi wallerian, akson, demyelinating, demyelinating patomekanisme NMJ disease patomekanisme periferal disease klasifikasi periferal disease berdasarkan lokasi GBS

LO Case 3 Hypoparathyroid 1. Explain the anatomy and histology of parathyroid gland 2. The structure of parathyroid hormone (PTH) 3. The synthesis, regulatory mechanism and secretion of PTH 4. Transport in circulation, action, and metabolism of PTH 5. The biologic effect of PTH on calcium and phosphate metabolism 6. The mechanism of action of PTH 7. Factors contribute to calcium metabolism 8. The various parathyroid disorders 9. Hypoparathyroidism and hypocalcemia : the causes and pathogenesis, clinical pictures, lab findings and principles of management 10. Hyperparathyroidism and hypercalcemia : the causes and pathogenesis, clinical pictures, lab findings and principles of management LO Case 5 Diabetes Mellitus Type 2 1. Describe anatomy and histology of pancreas gland 2. Explain insulin : synthesis, secretion, action, physiologic action of insulin on carbohydrate, fat, and protein metabolism 3. Describe the principle of carbohydrate metabolism and its relation to lipid and protein metabolism 4. Differentiate gluconeogenesis from glycolysis; process and regulation of glycogenesis & glycogenolysi; and control of blood glucose 5. Describe the lipid transport; disorder of lipoprotein metabolism; atherosclerosis process and principle management of disorder lipoprotein metabolism 6. Explain the secretion and action of glucagon 7. Know and define type 2 diabetes (TD2DM) and epidemiology of TD2DM 8. Understand and explain the etiology, pathophysiology, and clinical signs of TD2DM and its chronic complications 9. Explain the metabolic abnormalities in the development of TD2DM 10. Explain the prevention strategies of TD2DM 11. Explain the principles of the management of TD2DM 12. Explain the pharmacological properties of OAD 13. Explain the pathophysiology of chronic complications in TD2DM: macroangiopathy, microangiopathy and dislipidemia 14. Explain and summarize the prognosis of TD2DM and its chronic complications 15. Understand the definition of gestational diabetes 16. Understand the effect of diabetes on intrauterine development, and effect of pregnancy on the diabetic mother, diabetes complications, and on fetus 17. Define and explain the pathogenesis of gestational diabetes 18. Explain the principles in management od diabetes in pregnanacy LO Case 6 Diabetes Mellitus Type 1 1. Understand the definition and pathogenesis of Type 1 DM 2. Explain the pathophysiology of Type 1 DM 3. Describe the clinical manifestation of patient with Type 1 DM 4. Explain the principle management of patient with Type 1 DM 5. Understand the influence intercurrent illness and stress hormone in Type 1 DM patient 6. Understand the pathophysiology of DKA 7. Understand the principle management of DKA 8. Understand insulin induce hypoglycemia 9. Describe the clinical manifestation and principle management of hypoglycemia 10. Explain the prevention of acute complications of Type 1 DM