MicroVacuum

Integrated Optical Chemical and Biochemical Sensors

presents

OW 2400c
COATED OPTICAL WAVEGUIDE GRATING COUPLER SENSOR CHIP
Grating Dot mark

W
I
TECHNICAL SPECIFICATION
A (coating)
F (waveguide film )
Diffraction grating
Surface relief structure:
H S (substrate glass )
depth~20 nm
L Grating periodicity:
2400 lines/mm (0,4166 µm)
Introduction Grating area dimensions:
The optical grating coupler sensor responds to the length ( l )~2 mm
change of optical refractive index of the liquid or width (w)=16 mm
gas cover medium and to the adsorption or binding Grating lines direction:
of molecules on the surface. parallel to the short edge of the sensor chip
Dot-mark:
The optical grating coupler sensor chip is based diffraction grating is uppermost, when dot mark or
on a fine optical grating prepared on a thin number is in the upper right corner
waveguide layer carried by a glass substrate. The
optical grating couples the light of a He-Ne laser
at a given resonance angle into the waveguide Planar monomode waveguide
layer. This incoupling angle is very sensitive to the Waveguide material (SOL-GEL)
presence of adsorbed molecules and to any SixTi(1-x)O2 , where x=0,25±0,05
change of refractive index of the medium covering Waveguide film
the surface of the chip. By precise measurement refractive index (nF)=1,77±0,03
of the incoupling angle, the amount of the thickness (dF)=170-220 nm
adsorbed material can be determined with ultra Substrate glass slide
high sens it ivit y. OW 2400 chip implements a length (L)=48 mm
coating layer on the waveguide surface, that width (w)=16 mm
modifies the optical, chemical or biochemical thickness (H)=0,55 mm
properties of the chip to the required extent. refractive index (nS)=1,53
Other substrate sizes are available on request.
OW 2400c sensor chips are used in high-resolution
optical waveguide lightmode spectroscopy (OWLS).
Coating on the sensor surface
Full coverage of the surface is standard, while partly
Main biosensing applications coverage is available on request.
• Adsorption of proteins at surfaces Thin films (~10 nm):
• Ligand/receptor binding (antibody/antigen) SiO2; TiO2; Ta2O5; ITO; ZrO2
• Immunosensing Other dielectric coatings are available on request
• Drug screening Thick films:
• Protein - lipid bilayer interactions PTFE, silicone etc. for passivation
• Protein - DNA interactions Functionalization:
• Molecular self-assembly & nanoscience Silanization with APTS
• Analysis of association and dissociation kinetics Other functionalizations are available on request,
• Kinetics of adhesion, growth and spreading of for updated information see our web site.
animal cells
• Food monitoring
MicroVacuum Ltd.
Kerékgyártó u. 10., Budapest, H-1147, Hungary ; Tel: +36 1 252 1991; Fax: +36 1 221 7996
E-mail: info@microvacuum.com; Web: http://www.microvacuum.com/