GUMBORO DISEASE

Presented by

Dr. Arifur Rabbi DVM, MS

Deputy Manager (Veterinary Technical Services) Eskayef Bangladesh Ltd.

GUMBORO DISEASE

Synonyms: Infectious Bursal Disease (IBD) Chicken Aids Avian Nephritis

Gumboro is a highly contagious Immuno-supressive Viral Disease of chicken Causal Agent: Gumboro Virus
Specific Factor: Most Severe : 3-6 Week of age But Leghorn Chicken: Up to 18 week of age Economic Impact:
1. Direct mortality that can reach levels in excess of 40%, 2. Secondary infections, due to a suboptimal immune system.

MICROBIOLOGY
Small, non-enveloped double stranded RNA virus.

Very stable hardy virus.

Able to survive a wide pH range (pH 2-12). Heat stable (viable after 30 minutes at 60C). High level of resistance to most commonly used disinfectants.

Survives in the poultry house environment for extended periods of time.

PATHOGENESIS
Gumboro No Antibody

Gumboro Low Antibody

Gumboro High Antibody

TRANSMISSION
Gumboro virus not transmitted vertically.
Virus can persists in the environment of the poultry shed thus infections are carried over from one cycle to the next. Mealworm could act as a vector carrying Gumboro Virus from one cycle to the next. Horizontal transmission through infected faeces, contaminated equipment (especially footwear) or other organic material.

Mealworm

CLINICAL SIGN

High Fever

Whitish Watery Diarrhea

Incoordination, Vent Picking,

Recovery occurs in 1 week

POST MORTEM

Swollen and hemorrhagic bursa

INFECTED BURSA

BURSA

Bursa Swelling

Days

Haemorrhage in thigh and breast muscle

Haemorrhage in breast & thigh muscle

Haemorrhage at the junction of proventriculas & gizzard

ND

If untreated

HOW??
Breakage of body defense mechanism (immunity) Any other infection occur easily

Coccidiosis

Salmonellosis

Mycoplasmosis

New Castle Disease

Others Infection

CONTROL
All infected litter and carcases of infected birds must be suitably disposed of away Use of through well planned disinfectant. Shed gape at lest 14 days

Use of vaccine
Overall maintain strict biosecurity

TREATMENT
No specific treatment but ..

Rx,
1. Ciproflox :1ml/L

2. Amprol :1 gm/ 1 L
3. Eskavit C :1 gm/ 3 L

+
Sugar (10gm/Liter Drinking Water)

Case Study
In a broiler farm containing 1000 birds with age 22 days. After post mortem examination you found Gumboro, New Castle Disease and Coccidiosis complication.

What will be your suggestion?