Professional Documents
Culture Documents
I. Suppurative inflammation.
II. Non suppurative inflammation:
Includes:
(1) Catarrhal inflammation.
(2) Membranous inflammation.
(3) Sero-fibrinous inflammation.
(4) Fibrinous inflammation.
(5) Serous inflammation.
(6) Haemorrhagic inflammation.
(7) Necrotizing inflammation.
(8) Allergic inflammation.
I.
SUPPURATIVE INFLAMMATION
(Pyogenic or Septic)
Cause:
Commonly
Staphylococcus
aureus.
Site: Commonly the abscess occurs in the
subcutaneous tissue, but occur in any
organ as the lung, brain, liver ... etc.
Composition of Pus:
o (1) Bacteria living and dead and their
toxins.
o (2) Liquefied necrotic tissue.
o (3) Inflammatory cellular exudate in the
form of polymorph- leucocytes, many
pus cells, macrophages and red cells.
o (4) Inflammatory fluid exudate.
opening
subcutaneous fat
pyogenic membrane
ACUTE INFLAMMATION
SUPPURATIVE / PURULENT - ABSCESS
PUS
=
PURULENT
ABSCESS
=
POCKET OF PUS
(1)
Ulcer
SINUS
blind ended tract open on surface
Fistula
Basic description: A fistula is an
abnormal tunnel connecting two body
cavities (hallow organ) (such as the
rectum and the vagina) or a body
cavity to the skin (like the rectum to the
outside of the body).
Example:
Entero-cutaneous fistula
Biliary fistula: connecting the bile
ducts to the skin surface, often caused
by gallbladder surgery
Rectovaginal fistula: between the
rectum and vagina
2- Furuncle (Boil)
Small abscess related to
a hair follicle or
sebaceous gland caused
by
staphylococcus
aureus.
Common sites are face
and back of the neck in
males and axilla in
females.
Multiple furuncles are
called furunculosis.
3- Carbuncle
Definition:
A type
of
localized
suppuration
forming multiple communicating suppurative foci in the
skin and subcutaneous fat
discharging pus through
several openings.
Cause:
Staphylococcus
aureus. Diabetes mellitus is a
common predisposing factor.
Sites: Areas where the skin
and subcutaneous tissue are
thick and tough as the back
of the neck and buttocks.
Pathology of Cellulitis
The basic pathological changes
are similar to those of abscess
with the following differences:
(1) Failure of localization because
of absence of fibrin (No pyogenic
membrane).
(2) The necrosis is extensive
(3) Pus formation is slow. Pus is
thin in consistency and may
contain many red cells i.e.
sanguineous.
Complications:
(1) Acute lymphangitis and
lymphadenitis.
(2) Septicemia.
(3) Neurofibromatosis
A
hereditary
familial
disease transmitted as a
dominant trait. The disease
is characterized by:
(a) Multiple neurofibromas
which appear as small firm
nodules in the skin along
the
course
of
the
cutaneous nerves.
(b) Cafe au lait skin
pigmentation.
(c)
Pigmented
iris
hamartomas called Lisch
nodules.
Malignant
tumours:
Malignant
Schwannoma
(neurofibrosarcoma).
Multiple neurofibromas
Plexiform Neurofibroma
Malignant Neurofibroma