BLOK 10

INTRODUCTION

DR Dr TAUFIK INDRAJAYA SpPD KKV FINASIM

Divisi Kardiologi
Departemen Ilmu Penyakit Dalam
FK Universitas Sriwijaya / RS dr Muh Husin Palembang

Contents
1.
2.
3.
4.
5.
6.
7.
8.

Introduction
Embriologi KV
Anatomi KV
Struktur Mikro KV
Fisiologi KV
Dislipidemia dan Kimia
Endotel
Histopatologi Infark,
RHD, Endokardium
Gizi Klinik pada KSV

09. Diagnostik KSV

10. Aspek Genetik KSV
11. Biomarker KSV
12. EKG
13. Peny Jantung Hipertensi
14. Disritmia
15. PJ Bawaan (Kongenital)
16. Peny Serebrovaskuler
17. Aspek Pencitraan KV
18. Peny Jantung katup

Contents .
19. Karditis
20. Aspek Pembedahan
21. Kardiomiopati
22. Farmakoterapi KV
23. Demam Rematik
dan PJ Rematik
24. Penyakit Pembuluh
Darah Perifer
25. Gagal Jantung

Praktikum
Tutorial
Skill Lab
Pleno

UJIAN

Further reading :
1. Hursts: The Heart.

2. Harrissons. Principles of Internal

Medicine
3. Buku Ilmu Penyakit Dalam PAPDI
4. Buku Ajar Kardiologi FK UI
5. Internet, Others

What does cardiovascular system do?

Cardiovascular System

Orientation of Cardiac Muscle Fibers

1. Anastomosing muscular fibers of the heart.

2. Purkinjes fibers from the sheeps heart.

Layers of the Heart

Coronary Artery System

The Conduction System

Electrophysiology of The Heart

The different waveforms for each of the specialized cells.

 After obtaining a history (ANAMNESIS)

, the physician proceeds to perform a
physical examination.
Depending upon the patient's condition
and suspected medical problem, a
physician may include one or more of the
following four phases of the physical
examination :

Inspection

Palpation

Percussion

Auscultation

IRD
RS Myria

Lulusan ..
Bekerja di tingkat pelayanan
primer.
Kondisi pelayanan minimal.
Harus mampu merujuk,
mendiagnosis tepat,
penanganan awal sampai tuntas.

Tingkat Kemampuan Lulusan.

Tingkat Kemampuan 1 :

Mengenali dan menempatkan gambaran-2 klinik sesuai

penyakit ketika membaca literatur

Tingkat Kemampuan 2 :

Membuat diagnosis klinik berdasarkan PF dan

pemeriksaan tambahan. Mampu merujuk secepatnya

Tingkat Kemampuan 3 :

3a : (2) + memutuskan dan memberi terapi

pendahuluan, merujuk kasus bukan emergensi
3b: (3a) + merujuk kasus emergensi

Penatalaksanaan
Suportif
Medikamentosa
Intervensional per kutan
Bedah, reparasi, penggantian
katup, bypass

Any Questions?

The Cardiovascular Continuum

Coronary
thrombosis

Myocardial
infarction

Sudden Death
Arrhythmia &
loss of muscle

Myocardial
ischaemia
STROKE

CAD

Atherosclerosis
LVH

Risk factors

oking, HYPERTENSION, cholesterol, DM

Remodelling
Ventricular
dilatation
Congestive
heart failure

Death
Dzau V. Braunwald E, Am Heart J. 1991

Atherosclerosis: A Progressive Disease

Plaque rupture

Monocyte

LDL-C

Adhesion
molecule

Macrophage

Oxidized
LDL-C
Foam cell

CRP

Smooth muscle
cells

Endothelial dysfunction

Inflammation

Oxidation

Plaque instability
and thrombus

CRP=C-reactive protein; LDL-C=low-density lipoprotein cholesterol. Libby P. Circulation. 2001;104:365-372; Ross R. N

Engl J Med. 1999;340:115-126.

Atherosclerotic progression:
Glagovs remodeling hypothesis
Progression
Compensatory expansion
maintains constant lumen

Normal
vessel

Minimal
CAD

Glagov S, et al. N Engl J Med. 1987;316:1371-1375.

Moderate
CAD

Expansion
overcome:
lumen narrows

Advanced
CAD

LVH

Congestive Heart Failure

ECG of Atrial Fibrillation (top) and

Sinus Rhythm (bottom)

TMT

Tranducer

ECHO

Aorta

V Ka

V Ki

A Ki

MSCT

Thanks for Attention