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Physiology of:

Oxygen Carrying System

V. Sutarmo Setiadji

4 February 2009

VSS

Cardiopulmonary:
1. Circulatory System
- Heart
- Vasculatory system
- Arterial
- Capillary
- Venous

2. Respiratory System
- Air pathway
- Lungs
3. Blood
4 February 2009

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Circulatory System
Functions:
- Circulating oxygen that come from
respiratory system, nutrients from the
digestive system, and hormones and
other chemicals, to all parts of the body
- Bring the waste from cell and
intercellular fluid to the excretory organs
maintain the stable conditions of the
internal environment (homeostasis)
Consist of:
- The heart and the blood vessels
4 February 2009

VSS

Jantung berfungsi memompa darah


merupakan 2 pompa
yang tersusun seri
Atrium kanan ventrikel.
kanan a. pulmonalis
paru v. pulmonalis
atrium kiri ventrikel
kiri aorta seluruh
tubuh vena kava
atrium kanan
20 Oktober 2008

VSS

Jantung tersusun
terutama dari otot
jantung.

12- Oktober - 200920


Oktober
20
Oktober
2008
2008

VSSVSS
VSS

Sifat-sifat otot jantung


1. Konduktivitas
2. Kontraktilitas
3. Automasi
4. Ritmisitas
5. Membentuk sinsisium
6. Mempunyai masa refrakter yang panjang
12- Oktober - 200920
Oktober
20
Oktober
2008
2008

VSSVSS
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Respiratory System
Function:
Uptake oxygen (O2) from the atmosfer
and deliver CO2 to the atmosfer
These function must be supported by circulatory
system

4 February 2009

VSS

Gas Law
The behavior of all gases is affected by three
factors: - the temperature of the gas,
- the pressure of the gas, and
- the volume of the gas.
The relationships among these three factors have
been defined in what are called the Gas Laws.
Five of these, Dalton's Law, Boyle's Law,
Charles' Law, Henry's Law, and the General
Gas Law, are of special importance to the diver.

Transport of Oxygen

1. From alveolus, O2 diffuse to the blood.


2. In the blood, O2 exist in two forms:
a. As a physical solution
b. In combination with ferrous iron atom in the
(the reaction is not oxydation but oxygenatio

Hb4 + O2
Hb4O2 + O2

Hb4O2
Hb4O4

Hb4O4 + O2

Hb4O6

Hb4O6 + O2

Hb4O8
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Haemoglobin (Hb) is a protein made up of four


subunits, each of which contains a heme moiety
attached to a polypeptide chain.
Heme is a complex of porphyrin and one atom of
ferous iron. Ferrous iron can bind reversibly one O
Molecule by reaction of oxygenation.

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1. Systems involve in the delivery of oxyge


the tissues are - the lungs
- the cardiovascular system
2. O2 delivery to a particular tissue depend
- the amount of O2 entering the lungs
- the adequacy of pulmonary gas excha
- the blood flow to the tissue
- vascular resistance in the tiss
- cardiac output
- the amount of O2 in the blood
- the amount of dissolved O2
- the amount of Hb in the blood
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- the affinity of the Hb for O2

06/02/15

VSS

Mass balance =
Existing body load
+
Intake or metabolic production

Excretion or metabolic removal

Sel mempunyai mekanisme pertahanan dalam


mempertahankan volumenya.
Mekanisme pertahanan itu sering disebut:
Regulatory volume decrease (RVD)
Atau
Regulatory volume increase (RVI)

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