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7)
I.
II.
Redox Reactions
V. Anaerobic respiration
VI. Respiration using other biomolecules
Cellular Respiration
Overall purpose:
convert fuels to
energy
animals AND plants
complementary to
photosynthesis
Cellular Respiration
Cellular Respiration:
(Exergonic)
Redox Reactions
as part of chemical reaction, e- are transferred
e- transfer = basis of REDOX reactions
(reduction) (oxidation)
Redox Reactions
Redox Reactions
Redox Reactions
Redox Reactions
NADH
ETC
O2 (H2O)
Steps of Respiration
Steps of respiration:
1. glycolysis
Coenzyme Junction
2. Citric acid cycle
3. ETC
4. Chemiosmosis
Cellular Respiration
Stages of respiration:
Cellular Respiration
1. Glycolysis
1 glucose (6C)
2 pyruvate (3C)
Glycolysis
Cellular Respiration
-inputs:
-outputs:
Cellular Respiration
Coenzyme Junction 2 pyruvate (3C)
Steps of Respiration
Stages of respiration:
Cellular Respiration
2. Citric acid cycle
few ATP so far
mitochondrial matrix
2 Acetyl CoA (2C) join
oxaloacetate (4C)
2 citrate (6C)
converted several steps,
4C lost (CO2)
e- to carriers
(NAD+, FAD)
Self-Check
Step of
Respiration
Inputs
Outputs
CO2/H2O
ATP
produced
e- carriers
loaded
Glycolysis
1 glucose
2 pyruvate
2H2O
2 net
2 NADH
Coenzyme
Junction
Citric Acid Cycle
Electron
Transport Chain
Oxidative
phosphorylation
Fermentation
Steps of Respiration
Steps of respiration:
1. glycolysis
- cytosol
Coenzyme Junction
2. Citric acid cycle
- mitochondrial
matrix
3. ETC
- inner
mitochondrial
membrane
4. Chemiosmosis
- inner membrane to intermembrane space
Steps of Respiration
Stages of respiration:
3. ETC
Proton
Motive
Force
Substrate-level phosphorylation
Cellular Respiration
3. Electron transport
chain (ETC)
lots of energy
harvested
released in stages
so far, 4 ATP
substrate P
many ATP oxidative phosphorylation
Cellular Respiration
Electron transport chain (ETC)
ETC e- collection molecules
embedded on inner
mitochondrial membrane
accept e- in turn
e- ultimately accepted by O2
(O2 reduced to H2O)
-outputs:
Steps of Respiration
Stages of respiration:
4. Chemiosmosis
ATP produced!
Cellular Respiration
4. Chemiosmosis
4. Chemiosmosis
Cellular Respiration
Four parts to ATP synthase:
Rotor, Stator, Rod, Knob
H+ must enter matrix here
Cellular Respiration
Summary of respiration
substrate-level
phosphorylation only
need to regenerate
e- carrier (NAD+)
pyruvate
converted to
acetaldehyde
acetaldehyde
accepts e ethanol produced
lactate
produced
Cellular Respiration
pyruvate - junction
O2 present
citric acid cycle
O2 absent fermentation
Self-Check
Comparison of aerobic vs. anaerobic respiration:
Aerobic
ATP
made by:
ATP per
glucose:
initial eacceptor:
final eacceptor:
Anaerobic
Glucose catabolism
= one option
Proteins:
amino group removed
a.a. enter Krebs Cycle
Self-Check
Step of
Respiration
Inputs
Outputs
CO2/H2O
ATP
produced
e- carriers
loaded
Glycolysis
1 glucose
2 pyruvate
2H2O
2 net
2 NADH
Coenzyme
Junction
Citric Acid Cycle
Electron
Transport Chain
Oxidative
phosphorylation
Fermentation
Lecture 2 Summary
1. Respiration Overview (Ch. 7)
Purpose
Redox reactions
Electron carriers & final electron acceptors
2. Locations of respiration steps, inputs/outputs, purpose, description (Ch. 7)
Glycolysis
Coenzyme Junction
Citric Acid/Krebs Cycle
ETC & Oxidative Phosphorylation [chemiosmosis]
3. Differences with anaerobic respiration (Ch. 7)
Purpose
Location
Inputs/outputs
4. Catabolism of other biomolecules (Ch. 7)
Proteins
Fats