Central retinal artery pressure and

carotid artery stenosis

(RAN SUN, XIAOYAN PENG, QISHENG YOU, LIQUN JIAO and JOST B. JONAS)
Beijing Opthalmoloy and Visual Science Key Laboratory, Beijing Institute of Opthalmology, Beijing
Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University,

TRI HARDINA SETIYO

11310380
PRESPTOR
DR. RAHMAT SYUHADA., SP. M

KEPANITERAAN KLINIK ILMU MATA

FAKULTAS KEDOKTERAN UNIVERSITAS MALAHAYATI
RS PERTAMINA BINTANG AMIN BANDAR LAMPUNG
TAHUN 2016

Introduction
Central retinal artery is a branch of opthalmica

artery and the internal carotid artery which is

cerebrovascular system. In some cases both
artery is relevant. So if there are obstacles in
carotid artery, it will cause abnormalities in
central retinal artery.

the
the
the
its

Goal of study
To explore the relationship between the pressure of

the central retinal artery and carotid artery stenosis.

Matherial and Method

This study was a prospective observational study of

clinical
Criteria for inclusion:

The group of patients with carotid artery stenosis or occlusion of the carotid
arteries
Patients developing cataracts or other eye disorders without problems in the
retina, optic nerve or the cerebrovascular system
Patients were treated at the Department of Neurosurgery at Xuanwu Hospital,
Capital Medical University (Beijing, China) between January 2014 and April 2014

Exclusion criteria:

Signs of iris neovascularization

neovascular glaucoma
Other types of glaucoma

Opthalmological Examination
All patients underwent routine ophthalmologic
examinations (vision acuity, tonometry, and slit
biomorphometry, ophthalmoscopy)
2. On the first day and the first day after oprasi
opthalmodynamometry
examination
(measurement diastCRAP)
3. Patients are given 1 drop of 0.5% tropicamide for
induction of mydriasis, after the 10 minutes given 1
drop of 0.5% propacaine to anesthetize the cornea.
1.

4. The

layout
of the opthalmodynamometer on
the surface of the cornea is anesthetized.
5. Give pressure to the eye via a contact lens little by
little until the CRA showpulsation.
6. Perform such
examination 10
times and averaged the results.

Statistical Analysis
Statistical analysis was

tested using SPSS with Ttest and the test results will be presented with 95%
confidence intervals (CI), the value of P <0.05.

characteristics of the sample

Sample (95)

Mean

Median

Men (51)

62,6 11,3
old

64 old

Diastolik
pressure

81 10
mmHg

80 mmHg

Consentration
glukosa

5,76 1,73
mmol / l

Consentration
lipoprotein
(HDL)

5,76 1,73
mmol / l

Consentration
lipoprotein
(LDL)

2.04 0.73
mmol / l

Trigliserida

1,45 0,66
mmol / l

Smoker (48)

Control (64)

62,4 15,0
old

62,3 old

Result
characteristics

CAS location and Degree

CAS

Interna

bifurcation

both of them

combined
with
extracranial
stenosis

32 (34%),

54 (57%),

6 (6%),

3 (3%).

Sub Group
CAS
surgery>
75%

Endartekto
Karotis
mi karotis stent arteri
implan
32 person

18 person

 In the multivariate analysis showed that levels significantly

higher CAS (correlation coefficient r = 0.75) with brachial

diastolic pressure (P <0.001) and diastCRAP lower (P
<0.001).
In the surgical study group at the beginning of the study
diastCRAP value is significantly lower than on the
contralateral side (P = 0.02). Value diastCRAP side sigifikan
surgery increased (P <0.001).
In the surgical study group at baseline, no significant
diastCRAP value with brachial diastolic blood pressure (P =
0.22)
Meanwhile, after the surgery, the value diastCRAP
significantly with brachial diastolic blood pressure (P = 0.001)

diastCRAP value and their assosiation with CAS

degree
Control group
without CAS

Diastole
brachialis

Standart
koefisien

Koefisien
regresi B

P < 0,001

, 0,54

0,995

Using the following regression equation

of the control group: diastCRAP = 0.995
x + brachial diastolic blood pressure of
8.85 mmHg)

Discussion
In this study in normal individuals and patients with

moderate
CAS
measured
value
with
opthalmodynamometry diastCRAP very significant
and linearly correlated with the level of CAS.

In line with this, the value of diastCRAP experienced

significant improvement after surgery CAS is

successful and the opposite occurs, and diastCRAP
correlated with brachial diastolic blood pressure. In
contrast to the pre-surgery.

Conclusion
Thus,

it
can
be
concluded
that
ophthalmodynamometry could be a useful tool in the
diagnosis and follow-up of the CAS. diastCRAP was
very significant and linearly correlated with the level
of inter-eye CAS in intra-individual, inter-individual
and intra-individual follow-up comparison