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Energy Storage/release
The Oxidation of Carbon Fuels is an important
source of cellular energy.
ATP serves as the principal immediate donor
of free energy.
Motion, active transport, signal amplification,
and biosynthesis can occur only if ATP is
continually regenerated.
The carbon in fuel molecules such as
glucose and fats - is oxidized to CO2, and the
energy released is used to regenerate ATP.
The carbon oxidation energy is used in some
cases to create a compound with high
phosphoryl transfer potential and I other cases
to create an ion gradient. In either case, the
end point is the formation of ATP.
Overview of glycolysis
Preparatory Phase
Fig 14-2
Reaction 1: Phosphorylation
Reaction 2: Isomerization
Reaction 3: Phosphorylation
Reaction 4: Cleavage
Reaction 5: Isomerization
The triose phosphate,
dihydroxyacetone
phosphate, must be
converted to
glyceraldehyde-3phosphate by the enzyme
triose phosphate
isomerase.
This reaction never
reaches equilibrium due to
glyceraldehyde-3phosphate is used as the
substrate of the next
Fig 14-2
Reaction 6: Oxidation
Reaction 9: Dehydration
1.
2.
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1.
2.
Summary
Stage 3: ATP is harvested when the threecarbon fragments are oxidized to pyruvate
Reaction of glycolysis