Nervous Tissue

Lab 5

Slide 22- Spinal Cord

Identify the grey matter and the
white matter
In grey matter see spinal neurons

Slide 23 Spinal Ganglion

These are large pseudo-unipolar cells
(one bifurcating axon means to
intersect or break). There will be
nuclei (easy to distinguish) and
encapsulating satellite cells.
Satellite cells are small flat cells which
are assumed to help regulate and
stablize the conditions surrounding the
ganglion cell bodies.

Myelonated axon fascicles that

contain sensory nerves from the

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Astrocytes and
neuron cell bodies

Grey matter

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Motor neuron

axon

Satellite Cell
Nerve Fibers
Neuron body

Satellite Cell

Cytop
lasm

Nu

u
cle

Satellite Cell
Satellite Cell

Capillary

Nerve Fibers

Dura mater, arachnoid mater, and

pia mater.
Mengies
Three membrane which envelope the
brain and SC.
Cerebral fluid found within
subarachnoid

Dura mater
Fuses with the periosteum
Outer most layer, derived from
mesoderm!
Keeps in CSF.
2 lamellae; superficial layer (the
periosteal layer) and the deeper layer
is the meningeal layer the actual
dura. For the spine; it is called the
dural sac or thecal sac

 Arachnoid
This is the middle layer
Spider web like, fibers attach to pia
mater.
Between arachnoid and pia is the
subarachnoid space which houses CSF.
Arachnoid cysts cause symptoms of
radiculopathy.
Radiculopathy nerve pain

The wall is of flattened arachnoid cells

and a vascular collagenous membrane

Pia Mater

This is the innermost layer

This is attached directly to the brain and SC.
Thinnest most delicate layer.
Anchored by astrocytes in brian and in the
spine through a series of small ligaments.
This helps maintain homeostasis.

Supplies blood to the brain and supporting

BCs, vascularization, aids in the production
of CSF, and enveloping and protecting the
brain.

Terlov Cyst
Interesting Pathology
Also called perineural cysts, these
are type II innervated meningeal
dilations, frequently seen in the
nerve-root sheaths of the dorsal root
ganglion.
Most often seen in the sacral portion
(base) of spine, but sometimes more
rostral.

Meningocele
Form of spinal bifida (improper
closure of the spinal column. There is
an out-pouching of the covering of
the SC that results in a defect of
bone and tissue. This pouch is filled
with CSF that leads to a mass.

Pseudomeningocele
This is an abnormal collection of CSF.
The fluid is without a meninge layer
specific but within the cavities of the
soft tissue.

Slide 19 Sectioned nerve

Perineurium is a sleeve of specialized
connective tissue formed by layers of
flattened epithelial-like cells.
Joined by tight junctions which act as a
protective layer; protect nerve fibers, passage
of macrophages, and maintaining internal env.

Endoneurium is a layer of loose CT that

merges with a lamina of type IC collagen,
laminin, and other proteins produced by
Schwann Cells.

Slide 20 Cerebrum
Appears folded, later of neuronal cell layers, the
somata, the perikaria. Note pyramidal neurons
with dendrites.
Meninges
Arachnoid (spider like fibers) and the pia mater (the
vascular tissue

Cortex
Molecular layer (superficial most), granular layer ( just
below molecular), pyramidal cells (primary motor
neurons, note their dendrites)

Medulla
Where you see the white matter

Where is the Cerebral Cortex??????

Grey Matter

White Matter

Slide 21 -- Cerebellum

Molecular
Layer
Cerebellar
medulla

Granular Layer
Purkinje cell
layer

Granular Layer

Purkinje Cell
Dendrite (projection)
Basket Cell, neuronal
body
White Matter

Neu
rog
Cel lial
ls

De
nd
rit
e

Purkinje Cells

White Matter

Basket Cells

Glomerulus
Glomeruli
Area

White Matter

Intestinal Wall Autonomic ganglia

These have nerves

jejunum