(A) Illustration of the splenic RBC filtration function (adapted from ref. 18).

Igor V. Pivkin et al. PNAS doi:10.1073/pnas.1606751113

2016 by National Academy of Sciences

 Schematic illustration of the limiting geometry considered in the theoretical framework.

Igor V. Pivkin et al. PNAS doi:10.1073/pnas.1606751113

2016 by National Academy of Sciences

 DPD simulation of a sequence of six steps (AF) as an iRBC parasitized by P. falciparum passes
through a slit in the human spleen at a constant pressure gradient of 0.64 Pa/m.

Igor V. Pivkin et al. PNAS doi:10.1073/pnas.1606751113

2016 by National Academy of Sciences