Professional Documents
Culture Documents
The Case of Millie. Millie, an elderly obese recommended an array of tests for her. These
woman went to her doctor due to her complaints of included testing for blood sugar and creatinine.
low energy and fatigue, blurry vision, dizziness, The laboratory also tested if Millies thyroid and
and pain in her ankles and knees. She also liver were functioning adequately. When Millies
informed her doctor that lately, she felt hungry all test results came back, everything was normal
the time and had to eat a lot because she could except for her blood sugar, which was 70 130
not be satiated. Plus, Millie claimed that she mg/dl even when she did not have breakfast prior
urinated several times throughout the day even to being checked. When it was checked again two
when she had less water intake. When she peered hours after she had her first meal, her blood sugar
closely, she also noticed that her urine seemed to level was 170 - 200 mg/dl.
have tiny bubbles in them. Considering all of
Millies complaints, her doctor
3
Chapter 1: An Overview of the Disease
4
Chapter 1: An Overview of
the Disease
How prevalent is diabetes? Statistically, the problem of
diabetes has been growing over the years. In 2012 alone
millions of Americans, regardless of their developmental
stage, suffered from diabetes. Specifically, around 29.1
million Americans have the disease, with 1.4 million more
being diagnosed annually since 2012. The diagnosis seems
to increase with age, with many of the Americans who suffer
from diabetes being in their late adulthood. In terms of pre-
diabetic condition, the age range is wider and individuals as
young as 20 years old can be predisposed to developing the
disease. In terms of race, diabetes is highest among
American Indians (15.9%) and lowest among non-Hispanic
white individuals (7.6%). In addition, approximately 13.2%
non-Hispanic blacks, 12.8% Hispanics, and 9.0% Asian
Americans suffer from diabetes. However, the above
statistics are true only for Americans. Worldwide, the
numbers are even higher. The World Health Organization
reports that between 1980 and 2014 the number of people
who have diabetes has reached hundreds of millions (i.e.
422 million). Globally, untreated diabetes is now considered
a major cause of stroke, blindness, kidney failure, and lower
5
Chapter 1: An Overview of the Disease
In terms of socioeconomic status, predicted by the World Health when the person last consumed food.
diabetes is more prevalent among Organization. If people do not do On the other hand, in fasting blood
individuals from the lower middle- anything to alleviate the sugar test, the person would have to
class and upper middle-class status. It consequences of diabetes, it will be fast overnight for at least 8 hours prior
is lower among people from low- considered as an epidemic sometime to being tested. When the person is
income households and high-income in the future. subjected to FBS, even water intake is
households. It should be noted, not allowed as water may alter the
though, that such picture of diabetes How is a person tested for result of the test. In oral glucose
as being more common in the middle diabetes? People are screened for tolerance test, the person has to fast
class is correlational rather than diabetes through initially testing their overnight too for the initial testing.
causal. Hence, in terms of blood sugar. The test, which is known Then the person is asked to drink a
socioeconomic status, the statistics as Glycated haemoglobin (A1C) test, sugary liquid and the persons blood
are not conclusive. What experts do measures blood sugar percentage in sugar is tested periodically for the
know about diabetes is that as of the haemoglobin. When two separate next two periods. This is done to
today, the percentage of people A1C tests show levels that are 6.5% or check for changes in glucose levels
suffering from diabetes continues to higher, the person is diagnosed with within the time of the sugary liquid
rise. In fact, there are projections diabetes. Aside from the A1C test, intake.
indicating that by 2050, for every there are also other options for
three adults, particularly those in the screening people who might have the
United States, one will be diagnosed disease. These options include
with the disease. Given the random blood sugar testing, fasting
aforementioned context, it is not blood sugar testing (FBS), and oral
glucose tolerance test. For random
7
impossible for diabetes to become the
Chapter 1: An Overview of the Disease
The Economic Impact of Diabetes. Diabetes does not only affect physical health; it
also has implications on the economy of the country. Unfortunately, the rising number
of people who have been affected by the disease has an inverted effect on global
economic conditions. For instance, productivity is reduced as people with the diagnosis
withdraw from the labor force due to complications brought about by the disease. In
the event that these individuals could not work, they are put on disability
compensation to help them alleviate the financial strain that the disease could cause.
This puts a dent on the economic resources of the nation and not just on them. In
addition, if individuals suffering from diabetes do not completely withdraw from their
jobs, they may still be absent many times from their duty hours. This is because they
have to set doctor appointments and medical check-ups when their symptoms are
painful or when they have to undergo regular checking or monitoring.
However, the preceding statements only discuss the indirect costs of diabetes.
In terms of direct costs, diabetes has forced the global economy to spend around $827
billion. In 2012, in the United States, the medical and health sectors spent a total of
$245 billion on diabetes-related expenses. On average, the money that the United
States has spent on individuals who have been diagnosed with diabetes is more than
double compared to the money that the country has spent on those who have not
been diagnosed with the disease.
8
Chapter 2: What are the Types of Diabetes
Type 1 Diabetes. Type 1 diabetes, which is
otherwise known as insulin-dependent diabetes
mellitus or juvenile diabetes, is due to a lack of
insulin in the persons body. This hormonal lack is
the result of what can be colloquially called a
mistaken identity attack. Normally, the persons
immune system only attacks germs and foreign
substances to keep the person healthy. However,
some people have immune systems that
mistakenly attack the beta cells in the pancreas,
thereby
For destroying
the body the bodys
to function capacity
properly, to produce
it is crucial for the
insulin. and the bloodstream to have insulin, since
tissues
the hormone is responsible for preventing the tissue
structure from deteriorating uncontrollably. In the
absence of insulin, the tissues cannot maintain their
structure and will break down into simple
compounds. When they are broken down into simple
compounds, they become part of the bodys by-
products. Eventually they leave the body through
urination. If this happens all the time, the ensuing
result is diabetes type 1.
9
Chapter 2: What are the Types of Diabetes
It should be noted, though, that it is natural for the pancreas ability to produce
insulin to decline as people grow older. But despite this decline, the insulin produced by a
normal individual is adequate for the body tissues. However, this is not the case for
individuals with type 2 diabetes. In the absence of sufficient insulin production and
utilization, the tissues of a person with this type of diabetes cannot transmit blood sugar
into the cells, thereby causing diabetic symptoms in the person.
Unfortunately, regardless of the type of diabetes that the person is suffering from,
there is no known cure for this disease despite its prevalence. Even so, with treatment and
healthy lifestyle changes, the symptoms of diabetes can be manageable.
11
Chapter 2: What are the Types of Diabetes
12
Chapter 2: What are the Types of Diabetes
However, aside from the above mentioned features, diabetes insipidus does not share the same hormonal problems of
diabetes mellitus. Rather than being caused by an insulin deficiency, it is caused by a problem in arginine vasopressin (AVP), which
is otherwise referred to as an antidiuretic hormone. AVP, which is responsible for maintaining normal urine volume and
concentration, can become problematic when there are damages to the kidney, the hypothalamus, or the pituitary gland. Normally,
the hypothalamus creates AVP and stores it in the pituitary gland. The only time that this anti-diuretic hormone is released into the
bloodstream is when the body becomes dehydrated. Upon dehydration, the hormone is released in the bloodstream, concentrates
urine and triggers the kidneys tubules to release water into the bloodstream instead of excreting most of it into the urinary
system. But when this mechanism malfunctions, the result is a large volume of diluted or watery urine exiting the body more than
the usual.
Depending on which part of the abovementioned mechanism is disrupted, people could suffer from specific types of
diabetes insipidus. The first is called central diabetes insipidus, which is caused by a problem in the production, storage, and
release of vasopressin. Such disruption is brought about by a tumour or meningitis or an inflammation in the pituitary gland or
hypothalamus. The second type is nephrogenic diabetes insipidus, which happens when the kidney has problematic tubules.
Defects on the kidney tubules could be due to drugs such as antiviral medications and lithium, or it could be due to a chronic
kidney disease. The third type of diabetes insipidus is primary polydipsia or dipsogenic diabetes, which is caused by unhealthy and
prolonged water intake. The brain has a thirst-regulating mechanism that signals to the person when he should take in water or
other forms of liquid. When such mechanism malfunctions, the result is the persons inability to correctly perceive real thirst,
pushing him to constantly drink. The last type of diabetes insipidus is gestational diabetes. A rare type of diabetes, this affects only
women who are pregnant. For women with gestational diabetes, their placenta creates an enzyme that destroys their vasopressin,
thereby resulting in the condition.
13
Chapter 3: What are the Symptoms of Diabetes?
Feeling Nauseous and Vomiting. When the body burns fat instead of glucose, ketones are produced. Ketones are organic
compounds, and makes the blood acidic. The increased acidity leads to stomach discomfort, which results to nausea and vomiting.
If ketone levels are high, this may also lead to a condition known as diabetic ketoacidosis (DKA). Because DKA can be life
threatening, individuals with diabetes are urged to monitor their blood ketone levels and to seek medical attention if and when it
becomes necessary. The buildup of ketones is more common among people with type 2 diabetes.
Wounds that Resist Healing. Another symptom that is associated with type 2 diabetes is slow healing of wounds. High blood
sugar levels tend to narrow down blood vessels. The narrowed blood vessels slow down the flow of blood and oxygen to the
wounds, making it difficult for the wounds to heal. Also, the sugar levels affect the red blood cells and prevent them from bringing
the essential nutrients to tissues that are involved in the healing process. Without the nutrients carried by the red blood cells, the
white blood cells in the tissues find it hard to fight wound infections. So, the wounds cannot heal as quickly.
Pain associated with complications of diabetes. Sometimes, the symptoms of diabetes cannot be felt by those who have the
disease. In fact, some experts believe that out of four individuals who might be suspected as suffering from the disease, one of
them would most likely not experience any of the symptoms. However, there are other health complications that could spring from
diabetes (e.g. neuropathy, stroke, and heart attacks). Along with these complications are various forms of physical pain that can
affect any part of the persons body. Some of these afflicted areas include the lower extremities of those suffering with diabetes,
such as their legs and their feet.
Irritability and Mood Changes. Although it may be unknown to most people, individuals with diabetes can experience irritability
and mood swings. These changes in mood are said to be a result of the rapid changes in blood sugar levels. Whether blood sugar is
high or low, some people with diabetes can feel irritable or sad. Sometimes the mood changes are not caused by the change in
body chemistry; they result from the strains and stress that come with having to deal with other symptoms and having to manage
their conditions.
17
Chapter 4: What are the Causes of the Two Major Types of
Diabetes
Possible Causes of Type 1 HLA and Viral Infections. The thing
Diabetes. For type 1 diabetes, with viral infections is that the
the definitive causes are not immune systems T cells produce
really known. However, experts antibodies that will help fight a
and researchers claim that there virus. But when the infection carries
are individuals who are a virus that contains the same
predisposed to developing type 1 antigen as the beta cells, or the
diabetes. One of the things that insulin producing cells in the
could set the stage for the pancreas, the T cells mistakenly
development of this disease is perceive the beta cells as part of the
their genetic makeup. Individuals virus and end up creating antibodies
who tend to develop type 1 that attack the beta cells. Similarly,
diabetes are those who have a when a virus infects the beta cells
specific human leukocyte antigen HLA, causing an alteration in the
(HLA) complex on their number 6 beta cells immunological
chromosome . This is said to elicit appearance, the T cells become
an immune system response in autoreactive, causing the
the body when a viral infection destruction of the infected beta
occurs. cells. When the beta cells are
destroyed, the insulin in the body is
significantly reduced. Some of the
viruses that are said to trigger onset
of type 1 diabetes are mumps,18
Chapter 4: What are the Causes of the Two
Major Types of Diabetes
Cows Milk and T Cells. Another possible cause of diabetes 1 is the protein that can
be found in the milk of cows. According to researchers Vaarala, Knip and Akerblom
(1999), a certain type of protein that has similar characteristics with glycodelin, a
protein that regulates the production of T cells, is attacked by the babys body when
the baby is fed cows milk. But because of the similarities that it shares with
glycodelin, the babys body also unintentionally attacks glycodelin. This increases the
production of T cells. Unfortunately, an increase in the production of T cells
inadvertently destroys the beta cells in the babys body. The researchers also claim
that bovine insulin, which is found in the cows milk, reacts with human insulin.
Among children with already existing diabetes-associated autoantibodies, this
reaction of bovine insulin can later on lead to insulin resistance, which can trigger
type 1 diabetes . Although the study of Vaarala and colleagues is empirical and
systematic, the plausibility of cows milk as a cause of type 1 diabetes remains
controversial in the scientific community.
19
Chapter 4: What are the Causes of the Two Major Types of
Diabetes
Possible Causes of Type 2 Diabetes. As with type 1 diabetes, the definitive causes of
type 2 diabetes mellitus are unknown. Unlike type 1, though, the risk factors associated
with the development of this type are clearer.
Genetics and Heredity. Type 2 seems to be genetic or hereditary. Time and again,
studies have shown that individuals with relatives and family members who have
diabetes have higher chances of being diagnosed with the disease. The risk is also
higher for those who have at least one parent who is diabetic.
An Inactive Lifestyle. Inactivity also Existing Health Conditions Other than Pre-diabetes.
puts the person at risk of developing Women who developed gestational diabetes when
the condition. People who spend their they were pregnant in the past and women who
time avoiding exercise deprive have polycystic ovarian syndrome are at higher risk
themselves of the opportunity to of developing type 2 diabetes compared to other
control their weight. The inactivity can women who have neither concerns.
lead to increase in weight, which as
previously mentioned, also increases Race and Ethnicity. Finally, a diabetes risk factor
the risk of diabetes. that may be startling to some people is race and
ethnicity. How this particular risk is possible remains
Pre-diabetes Condition. People who unclear. However, in various studies, it is apparent
also have a pre-diabetes condition are that individuals who are African-Caribbean, South
at risk of developing the disease. A Asian and Chinese, and those who are African are
pre-diabetes condition exists when predisposed to developing the disease. In fact,
the person has a blood glucose level compared to the general UK population, those who
that is higher than the average but are from South Asian communities have six times
not high enough to be considered as better chances of being diagnosed with the
indicative of diabetes. Otherwise condition. Those who have African and African-
known as impaired glucose tolerance, Caribbean roots have lesser chances of developing
a prediabetic condition can turn into the disease compared to the Asian group. However,
type 2 diabetes unless something is they are still three times at higher risk compared to
done about it. Not surprisingly, people the general UK population. Likewise, compared to
who are obese also have higher white people, Hispanics, Asian-Americans, and 21
Chapter 5: Diabetes Comorbidities and Complications
People who have diabetes often also suffer from other health complications. This article discusses some examples of comorbidities
of diabetes and health complications that arise from the condition.
Hypertension. Oftentimes people with diabetes also have high blood pressure or hypertension. Approximately 67% of people with
type 2 diabetes will also have these symptoms. Hypertension happens when blood pressure is higher than 140/90 (systolic
reading/diastolic reading) mmHg. For people with diabetes, an additional diagnosis of hypertension further endangers them and
puts them at risk for the development of macrovascular and microvascular diseases. Specifically, when not treated, the blood
pressure of people suffering from diabetes can lead to stroke, heart failure, or heart attack.
Non-alcoholic Fatty Liver Disease (NAFLD). This disease is a common comorbidity of type 2 diabetes mellitus, although it can
also be present in those with type 1 diabetes. In NAFLD, there is an increase in the circulation of free fatty acid in the body, which
means that fatty acids can also reach the liver. When this happens there is then an excess of triglycerides (TGs) in the liver, which
in turn increase resistance to insulin. Coupled with diabetes, obese individuals who have untreated NAFLD can ultimately be
diagnosed with cirrhosis.
22
Chapter 5: Diabetes Comorbidities and Complications
Dyslipidemia. Also known as hyperlipidaemia, is a rise in the plasma
cholesterol or triglycerides (TGs) of the body. At times both the levels
of plasma cholesterol and triglycerides are both higher than normal. It
may also be indicated by decreased levels of high-density lipoprotein
(HDL). People with type 2 diabetes are likely to have developed an
atherogenic combination of high TGs, low HDL, as well as elevated
levels of low density lipoproteins (LDL). Diabetic dyslipidemia, when
coupled with a sedentary lifestyle and high caloric intake, increases the
possibility that affected people could have cardiac arrest. Studies have
shown that this possibility is higher among women, although the
reasons as to why this occurs are not yet well explored. Dyslipidemia is
also believed to be caused by problems in the action of insulin among
people with diabetes together with hyperglycaemia, or the excess
levels of glucose in the bloodstream. However, in some clinical cases of
individuals suffering from type 2 diabetes, the connection of insulin
resistance to dyslipidemia is much clearer compared to
hyperglycaemias connection to the disease.
People who have been recently hospitalized due to their diabetes and a coronary, vascular, or carotid
concern are at high risk of having coronary artery conditions (CAD) and coronary heart disease (CHD). When
they possess this particular risk, they also have a higher likelihood of developing CVD. Some additional
factors that could contribute to the development of the disease are cholesterol levels, hypertension,
cigarette smoking, and medical history of CAD in the family, obesity, PCOS, high uric acid content, and
elevated lipoproteins. There is a need to manage symptoms that may be associated with cardiovascular
disease because it is one of the leading causes of death among those with diabetes. However, CVD can be
prevented; medical doctors recommend a change in lifestyle, along with taking low dosages of aspirin (for
those
Sleepwith lower risks) to high dosages of aspirin (for those with higher risks).
Disorders
Not having enough hours of sleep at night leads to health concerns like obstructive sleep apnea. Apnea is
a condition wherein people stop breathing while asleep so they end up suddenly jerking awake to catch
their breath. Catching their breath allows them to resume the flow of oxygen to their bodies and their
brains. Because sleep is interrupted many times throughout the night, sufferers end up being deprived of
the adequate rest that they need to function well during the day; hence they are usually sleepy and tired.
Unfortunately, sleep apnea is common among adult individuals with diabetes, affecting 2 out of 3
patients. Usually it affects diabetic individuals who are over the age of 65 rather than those who are
younger, although the possibility is still there.
24
Chapter 5: Diabetes Comorbidities and Complications
Sleep Disorders
Apnea can be treated through the use of a continuous positive airway pressure or CPAP machine. The
machine, which is used while the person is asleep, blows air into the throat through a hose and mask. The
air pressure prevents the throat from closing up and allows oxygen to flow continuously. People who use the
machine are less sleepy during daytime and have better blood pressure. People who suffer from the
disorder but who do not wish to use the machine are advised to lose 10% of their body weight to alleviate
themselves of their symptoms. They are also advised to not sleep on their back as it predisposes their
throat to close up more. Rather, they are encouraged to shift sleeping on their side and on their stomach.
Another sleeping problem that people with diabetes suffer from is restless legs syndrome (RLS), a
neurological disorder wherein people have uncomfortable sensations in their legs. These sensations, which
usually occur at night when people are supposed to be resting, can increase in intensity and can become
very painful. Sometimes they manifest in such a way that it would seem as if there is a surge of electricity
passing through the legs, while other times they manifest in twitching, throbbing, or creeping sensations.
Restless leg syndrome occurs more for diabetic individuals who also have kidney problems and neuropathy.
RLS is said to be related to a disruption in the function of the basal ganglia circuits of the brain. The basal
ganglia circuits utilize dopamine, which is an essential neurotransmitter that controls muscle movement
and activity. When its dopamine pathway is disrupted, involuntary muscle movements occur like the ones
during an RLS episode.
Doctors recommend exercising and stretching legs before going to sleep as a way to treat RLS. Similarly,
they encourage diabetic individuals to lessen their use of tobacco and reduce their caffeine and alcohol 25
Chapter 5: Diabetes Comorbidities and Complications
People with diabetes feel stressed out due to its symptoms. Stress is only the tip of the iceberg, and
individuals with diabetes are likely to experience other more serious psychological concerns, such as
depression. In fact, people with either type of diabetes suffer from depression two times more than the
average population. Moulton, Pickup & Ismail (2015) found out that type 2 diabetes and depression have a
shared mechanism, which can possibly explain their comorbidity. Both can increase activation of a
patient's innate immunity, which eventually results to a cytokine-mediated inflammatory response and
the dysregulation of the hypothalamic-pituitary-adrenal axis. This physiological occurrence can increase
resistance to insulin and can lead to depression, even resulting in high mortality levels. For type 1 diabetes,
though, there is less evidence of its specific physiological connection to depression, although correlations
between the two are significant.
Furthermore, statistics on the comorbidity of diabetes with other psychological disorders show that
the relationship between them is bi-directional. For instance, the two conditions could be independent
diseases, existing together because of their shared pathogenic pathways. It is also possible that diabetes
complicates an existing psychiatric disorder, or it could be the other way around, such as when medications
for a psychiatric disorder leads to an impaired glucose tolerance, resulting in diabetes. It is also possible for
both to overlap in terms of their manifestation, such as during panic attacks.
27
Chapter 6: What is Diabetic Neuropathy?
Autonomic Neuropathy. When the nerves that are commonly associated with daily body
functioning are damaged, autonomic neuropathy might occur. If the disease affects the
stomach and the intestine, the symptoms usually include feeling nauseated after eating
and vomiting of undigested food, early satiety and difficulty with bowel movements such as
diarrhea or constipation. If the persons heart and lungs are affected, the symptoms may
include an abnormal heart rate, blood pressure problems and shortness of breath. If the
persons bladder system is affected, the symptoms may include incontinence or leaking of
urine, difficulty urinating and feeling that the bladder still has urine even after having
urinated. Other uncategorized symptoms of autonomic neuropathy include unintentional
weight loss, vaginal dryness, erection concerns, irregular perspiration and heat intolerance.
28
Chapter 6: What is Diabetic Neuropathy?
Radiculoplexus Neuropathy. Otherwise foot or the shin, pain in the front part of
known as diabetic amyotrophy, the thigh, pain in the persons pelvis or
radiculoplexus neuropathy usually affects lower back, or pain in the persons chest or
nerves located on the hips, thighs, legs abdomen area. People with this kind of
and buttocks. Its symptoms are weight neuropathy may also suffer from Bells
loss, swelling of the abdomen, difficulty palsy or paralysis on either the left or the
rising or getting up once the person is right side of the face. Their vision may also
seated, intense and sudden pain in the be affected and they may find it hard to
thigh and hips or in the buttock, and focus their eyes particularly when there is
atrophy of thigh muscles. A diabetic aching behind one eye. Sometimes also,
patient who experiences this type of because eye focus is difficult, they may
neuropathy can gradually get better have double vision.
although the symptoms have a tendency
to intensify before finally lessening. If mononeuropathy is caused by a
compacted nerve, diabetic people may
Mononeuropathy. The last type of develop carpal tunnel syndrome.
neuropathy is mononeuropathy, which is Individuals who suffer from this condition
also referred to as focal neuropathy. The complain of a tingling sensation in their
term indicates that for this type of fingers, or if not their fingers, in their hand.
neuropathy, the damage is focused on a It is also possible that instead of the
specific nerve. It is very painful, albeit, it tingling sensation, they may complain of
has better prognosis compared to the fingers or hand numbness. In general, their
other three types. The nerve that is hand would feel feeble and they would be
affected by mononeuropathy is usually inclined to dropping things due to the
located in the face, the leg or the torso. weakness. They would then find it difficult
29
Chapter 6: What is Diabetic Neuropathy?
Factors Contributing to Diabetic Neuropathy. As earlier mentioned, nerves can be damaged when the person has high blood
sugar. Although it is unclear as to how this happens, experts have proposed the idea that the sugar content disrupts the nerves
from their signal transmission function. At the same time, such sugar content weakens capillary walls, cutting the flow of oxygen
and essential nutrients to the nerves.
But aside from the above, the extent of damage on the nerves is determined by risk factors such as a kidney disease, smoking and
the length of time the person has had diabetes and the persons ability to monitor and regulate blood sugar. With regards to the
first risk factor, if the persons kidney is damaged because of diabetes, toxins enter the persons blood thereby increasing the
possibility of nerve damage. Similarly, when the person smokes, the arteries become hardened and narrow. The more the person
smokes, the higher is the likelihood that the narrowing and hardening would occur. This occurrence eventually reduces the capacity
of the blood to retain a regular and undisrupted flow all throughout the persons body. When blood does not flow well, the flow of
oxygen is also compromised. Ultimately, the peripheral nerves become damaged and the person suffers from diabetic neuropathy.
Moreover, the longer the person has had diabetes, the higher is the possibility of developing neuropathy. When this risk factor is
added to the persons possible unhealthy practices in terms of blood sugar control, the end result is a diabetic disaster.
Signs that the Person Has to Take Action and Seek for Medical Help. If people suffer from diabetes and they want to
prevent, or at least decrease, the possibility of developing neuropathy, they should constantly monitor changes in their body. If for
example, they could not sleep because of a burning or tingling sensation in their hands and feet, or if they experience dizziness any
time of the day, it is advisable for them to visit their doctor. If they experience changes in sexual functions, urination routine and
digestion activities, they should also consider making an appointment with their doctor. Likewise, a wound that is taking long to
heal or a wound that is not healing at all can be another tell-tale sign that would indicate the need to seek for medical help.
(National Institute of Diabetes and Digestive and Kidney Diseases).
Although it is possible that any of the above mentioned signs do not immediately point to diabetic neuropathy, finding out earlier
about the truth is better than finding out later about it. As with other diseases, prevention is always better than the cure.
30
Chapter 7: The Diabetic Pregnant Woman and Her Children
When the Mother-to-Be Has Type 1 or Type 2 Diabetes. It is best to regulate blood sugar prior to getting pregnant
because high blood sugar levels could be harmful to the baby during first few weeks in the womb. Keeping blood sugar in
control includes engaging in physical activities, eating healthy and planning dietary intake, as well as taking
maintenance medicines that are not harmful to the foetus.
But how does diabetes affect the pregnant woman and the child she is carrying? On
the babys end, it is possible for the baby to have very low blood sugar immediately
after birth. During pregnancy, glucose from the mother passes through the
umbilical cord to the baby. This means that the baby could also have high glucose
level while inside the womb. But this glucose level can drop quickly once the baby
is born because the source is cut-off. The sudden drop can result to very low
glucose levels, which is unhealthy.
Similarly, the brain, heart, lungs and other organs of the baby develop during the
first 2 months of pregnancy. During this period, glucose is absorbed by the babys
cells to become fuel for the cell. But the cells can only absorb a certain amount of
glucose at a time, leaving excess glucose free to cross-link with proteins and fats.
change
When gene
the expression
cross-link and cause
becomes deformities,
permanent, such glycation
advanced as a cleft end
palate. In other
product cases the effect can cause life threatening
or AGE
conditions such as disrupted blood flow, a malfunctioning immune system
is created. Unfortunately, AGE has negative effects on the development of the baby defects in neural tube development and
abnormally
because shaped red blood cells. The mother may also develop preeclampsia during the second half of her pregnancy.
it can
This can induce hypertension and would cause an excess of protein to be present in her urine, which is a sign of possible
kidney damage. Preeclampsia can be life threatening for the mother and the baby and the only solution is for the mother
to give birth to her baby prematurely. This in turn can cause other health complications.
31
Chapter 7: The Diabetic Pregnant Woman and Her Children
When the Mother-to-Be Develops Gestational Diabetes. Sometimes, the woman only develops diabetes during the
later phase of her pregnancy. This condition is known as gestational diabetes and usually happens when the woman cannot
produce adequate insulin while she is pregnant. Usually, the detection window of the condition is between the 24 th and 28th week of
pregnancy.
A woman who is overweight has a higher tendency of suffering from gestational diabetes a likelihood that is further
increased if the woman had already given birth to a baby who weighed over 9 pounds. If the woman has a parent or a sibling with
type 2 diabetes, if she has been diagnosed with polycystic ovary syndrome or if she herself suffers from pre-diabetes, she also has
higher chances of being diagnosed with gestational diabetes.
Gestational diabetes affects the baby in several ways. First, the baby may be born bigger than the average because the
extra glucose that the mother transfers to the baby is stored in the babys body as fat. Even when the babys pancreas creates
extra insulin to regulate the high glucose level, the ratio of the two is still imbalanced. Second, the baby might suffer from
hypoglycaemia after birth, similar to the child of the mother with type 1 or type 2 diabetes . Third, the baby may be born with
jaundice, which is characterized by the yellowing of the skin and the whites of the eyes. The babys jaundice eventually goes away
but not without needing extra care and attention from medical professionals and the mother. Fourth, the baby might be born with
respiratory distress syndrome, a condition wherein the alveoli in the babys lungs do not stay open because of the absence of
surfactant, which is the coating of the alveoli. When the alveoli close up, air cannot pass through the lungs and breathing becomes
hard. Babies who have respiratory distress syndrome appear blue (cyanosis) because the presence of oxygen in their blood is
insufficient. This can be characterized by the nostrils flaring out and grunting when they exhale. To help babies breathe, a
ventilator has to be attached to them and surfactant can be provided to them through their windpipe. If babies with the diagnosis
do not receive proper treatment, they can suffocate, or if they do live, they can suffer with damages in their brain and other
organs. Fifth, the baby of a mother with gestational diabetes will likely grow up overweight and suffer from type 2 diabetes.
32
Chapter 7: The Diabetic Pregnant Woman and Her Children
What Should a Pregnant Woman with Diabetes Do to Keep Herself and Her Baby
Healthy?
A pregnant woman who suffers from diabetes should be given extra tests to help her throughout her
pregnancy. Her prenatal check-ups should include ultrasound exams to monitor the rate of her babys
growth. Kick counts should also be monitored to check the time in between her babys movement. The
babys heart rate should also be monitored to make sure that it matches expected heart rates of babies
when they are active inside the womb.
Regardless of the type of diabetes that she has, a woman who is pregnant should monitor her glucose
levels. Her doctor can help her set glucose level targets throughout her pregnancy. She can stick to these
target levels if she is wise with her food choices. She should ask her dietician and doctor to help her plan
her daily meals and snacks because she cannot risk suffering from hypoglycaemia due to not having the
right amount and type of food. If the pregnant woman suffers from hypoglycaemia, she is advised to
immediately take 3 or 4 glucose tablets or drink cup of any fruit juice or 1 cup of milk or eat 5 to 6 pieces
of candy. After 15 minutes, she should check if her blood glucose has increased to normal levels. If it is still
low, she is advised to have another serving of the aforementioned food until her blood sugar reaches a
normal level.
It would also be good for the pregnant diabetic woman to keep herself active throughout her pregnancy
since exercising can prevent glucose levels from shooting up. The most common form of exercise for a
pregnant woman is walking but there are other forms of exercise that may be beneficial to her. Naturally,
she has to ask her doctor prior to engaging in specific types of exercise to make sure that she does not put
herself or her baby in any risk.
If it becomes necessary, the pregnant woman can take insulin shots or medication for diabetes. However,
because medicine can interact with the type of food that people consume and the time that they consume
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Chapter 8: Treatments for Diabetes
Treatments for Type 1 Diabetes. The treatments needed by individuals with type 1 diabetes normally span their
entire lives. The main purpose of these treatments is to help them maintain their blood sugar levels within specific
ranges. Similar to people with type 2 diabetes, regular exercise and proper diet can help those with type 1
diabetes but they also need additional precautionary
measures such as the following:
IV Fluids. Since, individuals who suffer from type 1 There is another innovative possible cure for type 1
diabetes may also suffer from diabetic ketoacidosis, diabetes. A research on small molecule therapy
they may also need intravenous fluids to keep their suggests that type 1 diabetes can be prevented if the
electrolytes stable and prevent dehydration from destruction process that eliminates beta cells in the
occurring. body could be understood more. Through the therapy,
the size of the beta cells may increase thereby
Surgery and Transplantation. There are studies that leading to an increased production of insulin. At the
illustrate the possibility of treating type 1 diabetes same time, the test is expected to stimulate existing
through surgery and transplantation. An example of beta cells to generate new ones through the process
this is replacing the pancreas of patients with a of cell division. However, conclusive findings on such
healthier one. Unfortunately, not everyones body projects have not been established.
will accept a transplanted organ, so patients who
undergo this procedure need immuno-suppressant
drugs to accommodate the transplant. Instead of
transplanting the pancreas, Dr. Joseph Lancman
suggests transplanting beta cells. If beta cells are
transplanted, the individual with type 1 diabetes
would no longer need insulin and might even be
cured of his condition. Despite the promises brought
about by this procedure, it shares the problems of
pancreas transplantation in terms of possible
infection and the host body rejecting the transplant.
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Chapter 8: Treatments for Diabetes
Treatments for Type 2 Diabetes. Many times, for individuals with type 2 diabetes, doctors would primarily
recommend careful planning of food intake and exercising. Doctors highlight the need for these two ways of treatment
because type 2 diabetes is usually associated with a sedentarylifestyle
and and excess weight.
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Chapter 8: Treatments for Diabetes
Medications. There are also medications prescribed for people with type 2 diabetes and these may be taken orally or
injected directly into them such as when they wish to have insulin shots. These medicines have varying effects,
depending on their content and purpose. Some of these medicines are the following:
People with diabetes have to eat healthy so that they could control a sudden spike or
drop in their glucose levels. They also have to count how much carbohydrates they
have consumed. However, this does not mean that they could no longer enjoy mouth-
watering food. In fact, there are plenty of low-carbohydrate, low-calorie and low-sugar
meals that people with diabetes could enjoy while counting carbs at the same time.
39
Chapter 9: The Diabetic Diet: Carbohydrates and
Glycaemic Index
What Can Carbohydrates do to a Persons Why Count Carbs? One benefit of counting
Blood Sugar? Any type of carbohydrate, carbs is that it allows patients the freedom to
whether it is from desserts, sandwiches or bread choose the amount of carbohydrates they want
can raise sugar. When counting carbohydrates, to consume per meal so long as these are within
patients should remember that so long as the their daily limit. This prevents patients from
amount of carbohydrates are equal for two food feeling as if they do not have control over their
products that belong to separate food groups, food choices. Another benefit of counting carbs
they are bound to have the same impact on their is that it helps patients see that they can choose
glucose levels. So if patients eat one gram of ice from several food groups, even from those that
cream, it has the same effect as one gram of a they initially might have thought as taboo for
hoagie or pasta. Still, when choosing one source people with their condition. Finally, counting
of carbohydrates over another, patients may carbs is also a means to remind patients that
want to look into other ingredients of their item they need to test their glucose levels at least
because these have different effects on the three times a day, or once before each meal.
patients health.
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Chapter 9: The Diabetic Diet: Carbohydrates and Glycaemic Index
How is Counting Carbs Done? Before even attempting to count carbs, the Joslin Diabetes Center advises patients
to invest on a guide on the amount of carbs they should eat daily. Then, they should have a list of food and their
carbohydrate content. They can use this list when deciding
on their next food intake. Patients may also use nutrition labels of
food as their basis for counting carbs so to do this they must know
how to read these. Similarly, they need to understand that
portions are not equal to carb content. Sometimes what they may
take as a small portion may already have three times the amount
of carbs in it than what they originally anticipated. When patients
have learned the basics of counting carbs, they would have to
purchase measuring cups and a weighing scale to measure the
exact amount of carbohydrates in a specific item. Patients can
also use their hands to estimate how much food they need to eat
to keep up with their carb requirement. (Constance et al., 2015).
For instance the thumb is equal to a tablespoon, which is
approximately 1 serving of low fat mayonnaise. The tip of the
thumb is equal to a teaspoon or 1 serving of regular mayonnaise.
As for the hand, a palm (excluding the fingers) is approximately to
3 ounces of boneless meat while the fist is equal to 30 grams or a
cup of cereal when it is cooked.
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Chapter 9: The Diabetic Diet: Carbohydrates and Glycaemic Index
Can Diabetic Individuals Still Count Carbs when They Eat Out? Eating out poses a concern for people with diabetes because
many times the food that restaurants offer, even those that seem to be healthy, are laden with sodium and fat. However, patients can
still eat out and count carbs at the same time so long as they try to remember some key points. For instance, they have to remember
to review all the items in the menu before deciding on what they should eat. This can help them check which items will make them go
overboard and which wont. They could also try looking for restaurants that do have healthier options. In the event that they dont find
any, they can ask restaurants to serve them half of the meals portion while the rest can be to-go or they can share the other half with
their friends or family they are out with. Restaurants are usually happy to oblige their customers so those with diabetes can request
for their orders to be cooked in a specific way such as if they want to have less salt or less sugar, or if they want their salad dressing
to be served on the side rather than to be mixed in with the salad.
The Low Glycemic Diet. Glycemic index (GI) is referred to as a measure of how much carbohydrates in food affect blood glucose
levels. Since carbohydrates ultimately break down to simple sugar, it is logical for individuals with diabetes to monitor the GI of their
food. For this reason, some medical doctors recommend a low glycemic diet for those with diabetes. Many vegetables have low GI
such as cauliflower, green beans, lettuce, asparagus, eggplant, peppers, celery, snow peas and cucumber. There are also fruits with
low GI such as banana, oranges, plums, kiwifruit, grapes and cherries. Multigrain bread, wheat kernel, all bran, macaroni and sweet
potato also have low GI. Sweets on the other hand are high on GI so patients should refrain from consuming too much of these.
So Which Low Glycemic Index Food Should Individuals with Diabetes Choose? Whether their choice is bread or pasta, diabetic
patients would benefit more if they choose to eat food that is made of whole grain rather than refined grain. If this is their choice, they
would not miss out on flavor either because whole grain products are more flavorful compared to refined grain products. Raw fruits
and vegetables are also better options compared to those that have been processed and canned. There are also low GI recipes (e.g.
Spinach Pesto Pasta, Baked Potato topping, Spinach Chutney, Teriyaki Chicken Nibbles and Carnitas Bites) found online or in books so
patients do not have to feel as if they can only eat limited food varieties.
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Chapter 10: Things that Could Help a
Diabetic Person
Actively seeking help from medical professionals is one of the many things that
people suffering from diabetes would have to do in order to resolve their concerns.
Although medication may be a primary need, people suffering from diabetes would
also have to do lifestyle changes and maintain these for the rest of their lives. To ease
the transition for them, their family members could play a significant role in the
process. The personality that they are born with could also help them as they
continue living their lives as diabetic people. This article discusses in detail some of
the things that could benefit people with diabetes.
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Chapter 10: Things that Could Help a Diabetic Person
Along with self-efficacy, the idea of While it is true that being diagnosed with
determination sets the stage for the the disease could hit people really hard,
successful management of diabetes. when they believe that they can actually
Peoples self-determination springs from overcome this ordeal, a positive long
their source of motivation. Ryan and term change in theirlives stands very
Decis Self-determination Theory states possible. Psychological studies state that
that, at any given point in time, people when people have self-efficacy or they
could either be intrinsically or believe that they have the capability to
extrinsically motivated. For example, find solution to problems or challenges
they may strive hard to do well in their affecting them, it createsa positive
work because they like the rewards that attitude towards things. This positive
come with good performance. People attitude can motivate them to
suffering from diabetes are likely to accomplish anything. In the case of
follow the same mechanism. They may individuals with diabetes,if they are able
be punctual with their medication to motivate themselves to be positive
because they like the idea of being despite their condition, they are also able
rewarded with good health. It is also to achieve specific outcomes. For
possible that they are motivated to take instance, they reduce their stress and
steps towards exercising because they lower their chances of becoming
value exercise as a form to combat depressed over the disease. Furthermore,
sudden sugar spikes. People who have they increase theirchances of
diabetes should be aware of their succeeding over diabetes.
motivation orientation so that they may
follow through with positive changes in
45
The Persons Goals. The Decision to Have a Lifestyle
Change.
The aid given by self-efficacy and Medication can help the person with
determination will not persist if it is not diabetes. Still, medication cannot solve
coupled with the actual setting of everything. The person has to make a
personal goals. Goals can give people lifestyle change and this does not only
suffering from diabetes the direction that mean losing weight or exercising as
they need so that any action they take, mentioned above. Rather, there is really
which may affect their condition, would a need to turn things around. For
not have drastic and negative effects on example, smoking is known to complicate
them. For instance, people with diabetes the condition of someone with diabetes.
who need to lose weight might want to It puts the person at risk for more health
incorporate exercising in their daily complications such as blindness and
regime. In the event that they falter and kidney failure and this is due to the
end up skipping one day of exercise, the nicotine in cigarettes. Hence, the diabetic
goal that they have set is there to guide person would have to quit smoking.
them back. Naturally, personal goals
have to be realistic or they would only
leave people frustrated and angry. So, if
people with diabetes haveto lose 60
pounds, they should not be setting
themselves up for failure by saying that
they will do their best to lose the 60
pounds in one month. Not only would this
goal be unhealthy, it would also be
impossible.
46
An Empathic and Genuine Support from Supportive and Understanding Family
Health Professionals. Members.
48
Chapter 11: Diabetes Myths and Truths
Number 2: People who suffer from diabetes can no longer be physically active.
Contrary to this belief, many studies illustrate that people with the condition can still lead
active lives. For instance, studies have shown that when individuals who are at risk of
developing type 2 diabetes engage in regular exercise, there is a decrease in their glucose
levels and an increase in the possibility of preventing onset of the disease. For those with
the diagnosis, exercise helps them lose weight, achieve better cardiovascular functioning
and lower mortality. An earlier study corroborates these findings. They recommend
resistance exercise three time a week for individuals with diabetes in order to reduce their
chances of developing cardiovascular diseases. Similarly, a study done this year yielded the
same findings on exercise. The researchers found out that many patients could decrease
their glycated hemoglobin level, systolic blood pressure, waist circumference, blood
glucose, body fat percentage, resistance to insulin, weight, and diastolic blood pressure
after only 12 weeks of continuous exercise, as well as increasing their muscular strength
and cardiorespiratory fitness.
Number 3: For Type 2 Diabetes, weight is all that matters. Because correlations
between type 2 diabetes and obesity are high, many people have this false impression that
the disease could only happen to those who are overweight, if not obese. However, the
National Institutes of Health has reported that just because someone is of normal weight,
this does not mean that the person could no longer suffer from type 2 diabetes. In fact
approximately 20% of people suffering from type 2 diabetes have normal body weight.
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Chapter 11: Diabetes Myths and Truths
Number 4: Fruits are always healthy. Diabetic individuals should eat fruits to satiate their sweet tooth. This raises a
red flag because in reality the sugar content of some fruits is still too high to not risk affecting blood sugar. Mangoes, for instance,
can make blood glucose levels shoot up and should be eaten in smaller quantities. The best way to know whether a fruit has low,
moderate or high sugar content is for patients to discuss this with their dieticians.
Number 5: Patients find insulin shots painful but addictive. Both of these claims are not factual. First, insulin shots utilize
syringe needles that are thin and small. So whatever pain may be present during an insulin shot would be negligible, especially for
the benefits of the insulin. Some patients even find it more painful when their blood sugar is monitored using a finger stick.
Why people think insulin is addictive is not difficult to understand. After all, it is usually injected into the body, much like morphine.
However, insulin is not a drug and is not addictive. It is a substance that the body naturally creates and uses to regulate glucose in
the bloodstream. Whereas drugs make people crave for them, insulin does not have the same effect.
Number 6: Type 1 Diabetes is more life threatening than type 2 diabetes. Regardless of the type, diabetes is a serious
diagnosis. It is a major cause of death in the world and has persisted in its growth and prevalence. When diabetes is left untreated,
it will lead to other problems like renal failure, heart attack, stroke and blindness. Depending on the severity of its complications,
diabetes can be life threatening.
Number 7: Type 1 diabetes is for children while type 2 diabetes is for adults. While it is true that the onset of type 2
diabetes commonly starts during adulthood, it could also be diagnosed when the person is young. It is unfortunate to note that the
combination of unhealthy lifestyle and genetic factors has put children at risk of developing type 2 diabetes. Likewise, type 1
diabetes can affect both adults and children and the symptoms may suddenly occur at any age group.
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Chapter 11: Diabetes Myths and Truths
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