Molybdenum Metabolism

Gandham.Rajeev
 Molybdenum is a component of xanthine
oxidase, aldehyde oxidase & sulfite
oxidase.
Sources:
Rich sources of molybdenum are liver,
kidney, meat, milk, whole grains, legumes
and leafy vegetables.
RDA:
200 micrograms/day.
 Absorption:
Dietary molybdenum is readily absorbed by
the intestine and is excreted in urine and bile.
Functions:
Molybdenum serves as a cofactor for
metalloenzymes.
Molybdenum is incorporated into:
Xanthine oxidase
Aldehyde oxidase
Sulfite oxidase
 Deficiency
manifestations
Molybdenum deficiency is rare in humans.

Its deficiency causes xanthinuria with low

plasma and urinary uric acid concentrations.

Molybdenosis is a rare disorder caused by

excessive consumption of molybdenum.

Symptoms:

Impairment in growth, diarrhea & anemia.

 Deficiency manifestations:
Molybdenum deficiency is rare in humans.
Its deficiency causes xanthinuria with low
plasma and urinary uric acid
concentrations.
Molybdenosis is a rare disorder caused by
excessive consumption of molybdenum.
Symptoms:
Impairment in growth, diarrhea & anemia.
Thank You