Fakultas Kedokteran Universitas Hasanuddin Makassar, 2006 DEFINITION Increase pressure within a comfined space (osteofascial space) that leads to microvasculary compromise and ultimately to cell death or tissue death ETIOLOGY 1. Trauma 3. Coagulopathies Fracture Genetic / hemophilia Hematoma Iathrogenic Gunshot (stab wounds) Acquired coagulopathies Animal/Insect bites/Snack bites 4. Others Post ischemic swelling External compression / most Crush injuries trousers, cast, thight dressings) Vascular damage Thight closure of fascial defects Electric injuries Burn-hypo / hiperthermia / 2. Edema related combustio Nephrotic syndrome Lost of conciousness (drug Frosbite (trauma dingin) overdose resulting in lying on Burns limb four hours) Over use injuries (over Infected : clostridiu perfringeus / training) walchii (gas ganggren) Prolonged tourniquet Mast trousers (celana ketat) ANATOMICAL LOCATION Forearm The most common site Anterior compartment of the leg Abdominal compartment syndrome Hand and wrist compartment syndrome Thigh compartment syndrome Foot compartment syndrome PATOPHYSIOLOGY Vascular congestion capillary beds occludedmuscle & nerve ischemiatransudation of colloid plasma into the surrounding tissues increase of tissue pressurearterial impaired (ellipsoid theory) CLINICAL PRESENTATION Pain (pain out of proportion) Paresthesias / anesthesia (dont pin prick test, because fibers smallerst, use two point discrimination test) Passive strestch severe pain Pressure tenderness PulsessnesThis is least releable of the examination are frequently not affective (a disorders microvasculature, major vessel) DIAGNOSIS Clinical presentation Measurement Whick catheter technique Slit catheter technique Stic catheter technique Continous infusion technique Needle manometer technique Normal pressure = 20-30 mmHg >30 mmHg need fasciotomy Necrosis of the muscle happened 8 hours in 30 mmHg intra compartement pressure Lab CPK, B.U.N., creatinin, aldolase, SGOT, LDH Urine Myoglobinuria, oliguria EMG SSEP PROPER INITIAL MANAGEMENT Constrictive dressing should be removed or splint Circumferential cast should be valued Limb should be placed at the level of the heart DEFINITIVE TREATMENT Fasciotomy = skin & fascia are left open on > 30 mmHg pressure Prophylactic fasciotomy should be performed on Tibial osteotomy Leg lenghtening Arterial repair Open tibial fracture Genereous fluids (IVFD) Alkalization urine by : bicarbonates or acetazolamide Antibiotic COMPLICATION Local ischemic contracture General Renal failure Cardiac arrest Septicemia / septic shock Death Patophysiology and cause death of compartment syndromes Trauma / injury