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Recommended literature:
Robert R. Crichton:
Biological Inorganic Chemistry, An Introduction, Elsevier,
Amsterdam, 2007
W. Kaim, B. Schwederski:
Bioinorganic Chemistry: Inorganic Elements in the
Chemistry of Life, John Wiley & Sons, 1994
The development and subject of bioinorganic chemistry
Classification
Essential elements
occur in a given concentration range,
they excert positive biological effects for several different
species
- Impurity elements
their quantity is a function of environmental effects
types : indifferent elements
beneficial elements
toxic elements
Biological effects of the elements
+ essential
normal
Physiological
response indifferent
-
toxic
Concentration in food
Essential elements
(conditions for classification)
For comparison: Pb: 80 mg/70 kg, Al: 100 mg/70 kg, Sr: 140 mg/70 kg
Factors affecting the selection of the trace elements
Source of acidity:
HCl (+ CO2, SO2)
Redox potential:
0,0 - 0,5 V 0,0 + 0,4 V ~ + 0,8V
Chemical constituents:
M+ and M2+ ions in increasing, while M3+ ions in decreasing
concentration
Elemental composition of earth crust and sea water (ppm)
4. W. Kaim, B. Schwederski:
Bioinorganic Chemistry: Inorganic Elements in the
Chemistry of Life, (John Wiley & Sons)
Hard-soft (kemny-lgy) sav-bzis elmlet (HSAB)
Lewis sav: elektronpr akceptor Lewis bzis: elektronpr donor
Csoportosts: polarizlhatsg (ionmret + tlts) alapjn
Hard (kemny): nehezen polarizlhat = kis mret + nagy tlts
Soft (lgy): knnyen polarizlhat = nagy mret + kis tlts
sav bzis
hard (s2p6) Li+, Be2+, Al3+, Ln3+ F-, O2-,...
Ti(IV), Mn(VII)