Dermatitis.

Eczema
Dermatitis
 Classification of dermatitis

Simple contact (artificial)

dermatitis Allergic

Contact Toxicoderma
Simple contact (artificial)
dermatitis
 Etiology :

Appears under the action of

of an obligatory
(unconditional irritants), by
which dermatitis is caused
in any subject
 Obligatory stimuli include:
Concentrated acids and alkali
High and low temperatures
Friction, the prolonged pressure
Electricity
UV rays
The ionizing radiation
Salts of heavy and alkali metals
Biological
Weapons of massive destruction
 Clinical signs:
Appears in the place of the action of the
irritant
Disappears after the elimination of the
irritant
Process is focal
Effect is asymmetric
Boundaries are clear
Is manifested by erythema, by bullae and
papules
Simple contact dermatitis
Burn of the second
degree
 Burn of the
third degree
 Contact
dermatitis
Simple contact dermatitis
Simple contact dermatitis
Frostbite of the third degree
Simple contact dermatitis
Chemical burn of the third degree
Electricity effect
X-ray ulcer
X-ray dermatitis
Solar dermatitis
Phytodermatitis
Mechanical dermatitis
Dry corns
 Allergic
dermatitis
 Classification of the allergic dermatitis

Contact allergic dermatitis Toxicoderma

 Etiology:

is caused by facultative
(conditional) irritants after the
preliminary sensitization of the
organism
Ways of the penetration of
allergen into the organism:

Contact allergic dermatitis:

Through the skin
 Ways of the penetration of
allergen into the organism:
Toxicoderma:
Through the respiratory
tract
Through the GIT
Parenteral
Contact allergic
dermatitis
 Clinical signs of contact allergic
dermatitis:

Process is focal
Eruptions are asymmetric in the
place of contact with the allergen
Boundaries are clear
Rash is polymorphic (spots, papules,
bullae and the pustules)
Contact allergic dermatitis
Contact allergic dermatitis of the face
Contact allergic
dermatitis of the
face
Contact allergic
dermatitis of the
face
Contact allergic dermatitis
Contact allergic dermatitis of the inguinal region
Contact allergic dermatitis of feet
Contact nickel dermatitis
Allergic dermatitis of palms
Contact allergic dermatitis of the face
 Contact allergic
dermatitis of hand
Allergic heylitis
Toxicoderma
 Clinical signs of toxicoderma:

Process is diffuse
Eruptions are symmetric
Boundaries are ill-defined
Rash is polymorphic
Diffused allergic
dermatitis
Diffused allergic dermatitis
Toxicoderma
Toxicoderma
Toxicoderma
Toxicoderma
Toxicoderma
Erythroderma
Erythroderma
Erythroderma
Toxicoderma should be
differentiated with:
- Zhiber`s pink lichen
- Psoriatic erythroderma

- ichthyosis
- Late skin porfiria
- scabies
- scabies,complicated by
dermatitis and eczema
Scabies with eczematization
Scabies with eczematization
Scabies with eczematization
Scabies with eczematization
Scabies with eczematization
- Darie disease
- Lichen ruber planus
- syphillis
Photodermatitis
Photodermatitis
Photodermatitis
Photodermatitis
Photodermatitis
Photodermatitis
Layell`s syndrome
 Layell`s
syndrome
 Layell`s
syndrome
Layell`s syndrome
Layell`s syndrome
Layell`s syndrome should be
differentiated with:
- Stiven-Johnson
syndrome
- bullous epidermolisis
Bullous epidermolisis
Bullous epidermolisis
Bullous epidermolisis
Bullous epidermolisis
Bullous epidermolisis of hands
Bullous epidermolisis
Nikolsky
symptom
- pemphigus
Atopic dermatitis
Atopic dermatitis
Atopic dermatitis
 Atopic
dermatitis of
legs
Atopic dermatitis
of legs
Atopic dermatitis of mammary glands
 Perioral
dermatitis
Atopic dermatitis with follicular papules
Atopic dermatitis of the vulva
Urticaria
Urticaria
Urticaria
Urticaria
Quincke`s oedema
Urticaria
Quincke`s oedema
Cold urticaria
Pigment
Urticaria
Pigment mastocytosis
Pigment urticaria
(urtical
dermographism)
 Urtical
dermographism
Urtical dermographism
Fixed drug
erythema
Fixed drug toxicoderma
Hyperemia from the
agitation
(vasomotoric
reaction)
Hyperemia of
the face after
the bottle of
wine
Eczema
 Classification
True
Occupational
Infantile
Microbial
Seborrheal
Dishydrotic
Tylotic
 True eczema

Begins on face and hands

Eruptions are symmetrical
Process is extended
Boundaries are ill-defined
True polymorphism
Tendency towards vesiculation and
the exudation (weeping)
 Stages of development

Exudation

Vesicles Crusts

Papules Scales

Erythema Pigmentation
 True
eczema
Generalized eczema
Eczema of the fingers
Eczema of the palms
Eczema
True eczema
True eczema
Numular eczema
Numular
eczema
Numular eczema
Numular
eczema
Dishydrosiformous eczema
Hyperkeratotic eczema of the palms
Dyshidrosiformous eczema
Dyshidrotic eczema
Dishydrosis
Dishydrosis
Damages of fingers in case of eczema
Infantile
eczema
Clinical attributes
the same as true
eczema has.
Exudative
diathesis
Infantile eczema
Microbic
eczema
 Microbic eczema

Begins more often on shins

Eruptions are asymmetrical
In the beginning the process is focal
Borders of focuses are well-defined
Eruptions are polymorphic with
prevalense of pyogenic elements
Initial stage of
venous
hypertension
Teleangiectases, initial stage of
venous hypertension
 Varicous disease,
hyperpigmentation
Trophic ulcer
Trophic ulcer
 Paraulcerous
microbial eczema
Paraulcerous
microbial
eczema
 Microbial
eczema of
shins
Microbial eczema of shins
 Microbial
eczema of
shins
Paratraumatical eczema
during treatment
Microbial eczema
Seborrheic
eczema
 Places of
localisation of
seborrhea on
the face
Seborrheal
dermatitis
Seborrheal
dermatitis
Seborrheal eczema of the infants
Seborrheal
eczema
Seborrheal
eczema
Seborrheal eczema
Seborrheal eczema
Occupational
eczema
 Appears after effect from industrial allergens
Has clinical attributes of true eczema
Appears more often on the opened parts of the
body
Similar clinical eruptions appear at other workers
of the same profession.
There is clinical improvement of the health during
a long break in work and an acute condition when
returning on manifacture.
Positive skin test with the industrial allergens
Compressive skin tests
Positive skin tests
Technics of perfomance of the
scarificational test
 Technincs of
the
perfomance of
the
intracutaneous
test
 Positive
intracutaneous
test
 Mechanism of
development of the
allergic reaction of
the immediate type
Antigen Macrophage Il-I

T - helper

Il-II
Ig E
Forerunners of the
effector cells
Ig E

Plasmatical
cells
Ig E
 Imuune deficiency

Plasmatical cell T - supress.

Immune
Ig E complex
Ig E complex
Immune

Basophil Mast cell

Histamine
Histamine
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs

Inflammation
 Histamine

Antihistamine drugs
 Histamine

Early cancelling
of antihistamine
drugs
 Histamine

Early cancelling of
antihistamine drugs
 Histamine

Early cancelling of
antihistamine drugs

Inflammation
Antihistamine drugs
HI-blockators
 Antihistamine
drugs decreasing
level of histamine
in blood
 Mechanism of
development of the
allergic reaction of
slowed-down type
 Ag

Il Macrophag Il
e
T-help T-supr

Il
Supressive factor

T ef
Hypersensitivity of the slow-down type
 T ef Deficiency
Hypersensitivity of the slow-down type T supr

Factors of
inflammation
Histamine
 T ef Corticosteroid hormons
Hypersensitivity of the slow-down type
 Treatment of
dermatitis and
eczema
General treatment
Hyposensibilisators
Glucocorticoids
Local treatment
Medicinal forms
Solutions for lotions
Shaken up mixes
Pastes and ointments
Corticosteroid drugs
for external
application
Complications of the
external
corticosteroid
therapy
 Peryoral
dermatitis
Peryoral dermatitis
Atrophy of the skin in case of long treatment
with hormonal ointments
Thanks for
the
attention