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THE RESPIRATORY
ORGANS FUNCTION
Drugs affecting the respiratory organs
function
anticough drugs;
expectorants;
breathing stimulants;
drugs used for bronchial asthma;
drugs used for lungs edema
COUGH
PRODUCTIVE
Sputum with significant viscous-elastic
properties:
- muco- and proteolytic drugs
Sputum with significant adhesive properties: NONPRODUCTIVE
- drugs which stimulate production of surfactant Cataral inflammation (usually viral),
Decreasing of speed of mucociliar transport with reflector and central cough:
unchanged properties of sputum:
- anticough drugs
- drugs which stimulate ciliar function
Signs of allergic reaction:
Significant disorders of bronchial permeability,
morphological changes of bronchi (atrophy of - antihistamine drugs
mucous membrane, bronchial stenosis), Bronchospasm:
excessive production of mucus: - broncholytics
- alkali inhalations
Signs of allergic reaction with increased
histamine activity:
- antihistamine drugs
edema
mediators
increase microvascular permeability/ leakage
mucosal thickening & airway swelling
airway rigidity
To remove attack of bronchial asthma
Broncholytic drugs:
Adrenomimetics (α, β-adremonimetics, β-adrenomimetics, β2-
adrenomimetics)
Methylxantines
Cholinoblockers (M-cholinoblockers, ganglionblockers)
Zileuton
- a 5-lipoxygenase inhibitor
Zafirlukast
- a leukotriene-receptor antagonist
improved symptoms