Pharmaceutics presentation

SUGAR COATED TABLETS

 Contents
• Genral introduction on 1) Tablet
2) Tablet coating
• Sugar coated tablet
a) Introduction
b) Advantages
c) Disadvantages
d) Raw materials
e) Steps involved
• Biblography
• Credits
 General Introduction
Tablets
Tablets are solid dosage forms each containing a unit
dose of one or more medicaments .They are intended for
oral administration. Some tablets are swallowed whole or
after being chewed , some are disolved or dispersed in
water before administration. Some tablets are swallowed
whole or after being chewed, some are dissolved or
dispersed in water before administration and some are
retained in the mouth where the active ingredient is
liberated
Because of their composition , method of manufacture or
intented use , tablets present a variety of characteristics
and consequently there are several categories of tablets .
Tablets may be coated . Where coating is essential , the
monograph states ' The tablets are coated ' . In all other
cases , coating is optional . Unless otherwise directed ,
tablets may be coated in one of the different ways .
Tablet coating
“Tablet coating is the application of coating material to the
exterior of a tablet with the intention of conferring
benefits and properties to a dosage form over the
uncoated variety.”
As per I.P-
“Tablet coated with mixture of various substances such as
resins, gums, inactive and insoluble fillers, sugars, waxes,
etc.”
Why To Coat ???
• Mask Bitter taste
•Mask unpleasant odour.
• Protecting the drug from surroundings.
• To increase the Stability.
• Handling & ease of ingesting by patients.
• Mechanical protection from breakage.
• Avoid Light incompatibility.
• Protection from Environmental Oxidation.
• In- elegent core.
Introduction
Sugar coating is the most conventional multistep coating
process.
• As the name suggests, this process involve application of
sugar (sucrose) based coating solution to the tablets.
• It is carried out in coating pans having variable capacities
& mounted at an angel of 40 Degree celcius
• Its use of labour is more, require a fair degree of skill.
Advantages of Sugar coating -
1. Cheap, safe coating material
2. Cheap coating machine
3. Good patient compliance
4. Can be reprocessed
5. Require less hardness core
Disadvantages of Sugar coating-
1. Time consuming process.
2. High weight gain.
3. Increase in packaging & shipping.
4. Required trained personnel.
5. Imprinting problems.
Raw Materials for Sugar Coating -
• Sugar & it’s Subtituents:Glucose, lactose, isomalt , sugar
,alcohol
• Binders:Acacia, gelatin, PVP
• Coloring agents:Water soluble (dyes), water insoluble
(lakes)
• Anti- Adherents:Talcum, colloidal silica
• Fillers:CaCO3 , CaSO4 , starch, talcum, TiO2
• Polishing Agents:beeswax, carnauba wax, paraffin
• Other agents:Flavouring agents, surfactants