Professional Documents
Culture Documents
SYNDROME
Arien Rianti 1315207
• The movement of food and waste through the GI tract (“motility disturbance”)
• Heightened experience of pain in the internal organs (“visceral hypersensitivity”)
• Changes in the gut’s immune defenses (“altered mucosal and immune function”)
• Changes in the community of bacteria in the gut (“altered gut microbiota”)
• Changes in how the brain sends and receives from the gut (“altered central nervous system
processing”)
Epidemiologi
• Population-based studies estimate the prevalence of irritable bowel
syndrome at 10-20% and the incidence of irritable bowel syndrome at
1-2% per year.
Manifestasi Klinik
• Altered bowel habits
• Abdominal pain
• Abdominal bloating/distention
• Altered bowel habits in IBS may have the following characteristics:
• Weight loss
• Iron deficiency anemia
• Family history of certain organic GI illnesses (eg, inflammatory bowel
disease, celiac sprue, colorectal cancer)
• Screening studies to rule out disorders other than IBS include the
following: