Professional Documents
Culture Documents
Asplenia
Asplenia
Cancer
Cancer
recommendations
Review available
HIV
recommendations
vaccination in:
available
HIV
vaccination in:
diseases (IBD)
Primary immune
Primary immune
deficiency
deficiency
Psoriasis
Psoriasis
Inflammatory rheumatic
Inflammatory rheumatic
diseases (IRD).
diseases (IRD).
Materials and Methods
Data PubMed, EMBASE, Cochrane Library, and
Data
Sources
PubMed,society
professional EMBASE, Cochrane
websites (WHOLibrary, and
and NICE)
Sources professional
and society website
medical specialty websites(WHOsearchand NICE)
terms:
and and medical specialty website
((“Vaccination”[Mesh]) search terms:
OR “Vaccines”[Mesh])
and
searches ((“Vaccination”[Mesh]) OR “Vaccines”[Mesh])
AND “Guideline” [Publication Type]
searches AND “Guideline” [Publication Type]
Guidelines focusing on recommendations for
Guidelinesin
vaccination focusing on recommendations
adult patients (18 years) were for
Study vaccination
selected, in in adult and
patients (18language,
years) were
Study
selection selected,
English
in English
French
and and
French language,
published January 1, 2005 January, the
selection published January 1, 2005
31st of 2016 and January, the
31st of 2016
Data
Data
extractio
Titles and abstracts were screened by two
Titles and abstracts
independent were(AL
reviewers screened by two
and LPB)
extractio
n independent reviewers (AL and LPB)
n
Data Vaccination
Vaccination
Data
synthesis Informatio
Summariz
recommendations
recommendations
were listed by type
Informatio
synthesis
and
n was
n was
Summariz
ed
were
of listed(live
vaccine
of vaccine
vaccines
by type
and(live
and extracted ed vaccines and
inactivated
analysis extracted inactivated
vaccines)
analysis vaccines)
RESULT
Literature search results
389 citations
15 guidelines (Reasons for exclusion: irrelevant articles (n ¼ 149) (e.g. management of infectious
diseases, reports, safety studies, position on only one vaccine), guidelines in non-
immunocompromised patients (n ¼ 82), pediatric guidelines (n ¼ 61), non-English or French
language guidelines (n ¼ 42), animal recommendations (n ¼ 20), duplicates (n ¼ 10),:reviews (n ¼
Guidelines
6), guidelines' evaluations (n ¼ 5), sub-national recommendations (n ¼ 2).
Asplenic patients
Asplenic patients
Patients with oncologic malignancies
HIV patients
Hematopoietic stem cell
recipients
Inflammatory bowel disease patients
Primary immunocompromised patients
Patients with psoriasis
Inflammatory rheumatic disease patients
Solid organ transplant
recipients
Discussion
In some Guidelines a
countries, a valuable tool to improving the
sense of help clinicians quality of care
mistrust exists translate best and patient
research evidence
against into best practice
outcomes
vaccinee
review
systematic complete,
review and a unbiased,
comprehensive objective,
field transparent,
and repeatable.
Field review complete, unbiased, objective, transparent, and
repeatable.
Live vaccines are contraindicated immunosuppressive therapy or in HIV
patients with a CD4 count under 200/mm3
Few exceptions The MMR and the varicella recommended in seronegative
patients before transplantation or those with psoriasis and HIV
Renal transplant recipients mortality rate was 30% in varicella zoster virus infection
to better immunisation coverage for VZV large survey from Medicare of VZV
vaccination in patients with autoimmune diseases achieved the same protection
and the same safety as the whole population without high immunosuppression
the exclusion of
the exclusion
guidelines not inof
guidelines
English not in
or French
English or French
some guidelines
some
were guidelines
also partially
were also partially did not
built on existing did not
systematically
built on existing
recommendations systematically
recommendations appraise the
included appraise
guidelines the
for
included
guidelines were guidelines for
guidelines were quality
not strictly quality
not strictly
independent
independent
Conclusion