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bi·o·tech·nol·o·gy
n.
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Biotechnology has been around for
years. Farmers have been practicing
the science of crop improvement for
over 75 years. However, a lot has
changed in these 75 years. Scientific
and technological advances now allow
humans to manipulate genomes
directly at the level of single genes and
their constituents with great speed and
precision.
The modern biotech sector is relatively
new, and a new industry name has
been proposed –Life Sciences.
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Life sciences is an industry where biotechnology,
agriculture, food, drugs and chemicals converge.
Through the combination of these divisions, firms are
able to produce new research & products. Crops are
now being designed to produce feedstocks for plastics,
vaccines, and foods that help to prevent or ward off
disease.
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Biotechnology Park - A Concept
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A Coherent Network
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Hotspots/Bioclusters
BioBusiness hotspot or biocluster - a concentration of life
science and biotechnology-related institutions, laboratories, and
businesses.
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Life Sciences Cluster – Bay Area
More biotechs located here than anywhere else, > 30 companies founded each year
5 major research universities, 3 medical schools, availability of managerial and technical
staff
Home to 34% of active US VCs; receives one of the largest share of NIH funding
820 life science companies, 250,000 direct & indirect employees (85,000 in biosciences)
Ranked #1 in Market Cap—Northern California holds 24% of the $200 Billion Biotech
Market Cap
Ranked #1 in Venture Capital Investment—recipient of 34% of total U.S. VC funding
Ranked # 1 in Entrepreneurial Climate—most companies with an annual revenue growth of
more than 20% for four consecutive years
Ranked #1 in NIH Research Grants—$ 2.49 Billion in 2002
Ranked # 2 for the Number of Patents Granted in 2002
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Life Sciences Cluster – RTP
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Life Sciences Cluster – Massachusetts
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German BioClusters Bioinitiative BioRegio
Nord Greifswald-Rostock
(Hamburg-
Region Kiel-Lübeck)
Nordwestl.
Region
Nieder-
Bremen
sachsen
BioTOP
Berlin-Brandenburg
BioRegio N
(Braunschweig-
Hannover-
Göttingen)
BioRegio
Rheinland BioRegion
(Köln-Bonn- Halle-Leipzig
Aachen)
BioMIT
Mittelhessen BioRegio
(Marburg- Jena
BioRegion Giessen)
Rhein-Main
(Frankfurt-Mainz)
BioRegio
BioRegion
Regensburg
Rhein-Neckar-
Dreieck
BioRegio
Stuttgart/ Biotech-
BioRegio Neckar-Alb nologie Biotechnologie
Freiburg (Tübingen) Ulm München
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India’s Biotech Clusters
• IBPL Biotech
Park – Hikal,
Shreya,
Emcure,
Advinus,
others
• R&D – NCL,
NIV, Agharkar
• SP Biotech, ICICI
• MNC R&D Centres
Knowledge Park
– Monsanto,
AstraZeneca, GE, • Biological
Sigma-Aldrich manufacturing -
DRL, Shantha,
• Startups – Strand,
Bharat Biotech,
X-Cyton, Metahelix,
BE, Zenotech
Avesthagen,
Gangagen • Bioagri –
Emergent,
• Services –
Nuzeeveedu, JK
ReaMetrix, MWG,
CROs, Jubilant • R&D – CCMB,
CDFDRI, IICT
• Other – Apotex,
Aurigene
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Facts About Maharashtra
9.4 % of Country’s 50%Of India’s Foreign
Population ( Produces Trade is Handled By
19% of National output ) Seaports &
International Airport
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Sound Social Infrastructure
12 % of Country’s Universities
19 % of Management institutions
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Subsequent
Phases
• Jalgaon
• Horticulture • Nagpur
food • Copper,
processing manganese
coal-power-
intensive
• Nashik
Auto
General Industries • Chandrapur
Industries • Aurangabad
• Nanded
• Mumbai
Knowledge •Pune
Corridor •Sugar-based •Cotton
•Chemicals
•Paper
• Ratnagiri based
• Kolhapur
•Food
processing
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Bio-Tech and Pharma
• Contribute about 40% of the
total turnover
• Presence of International
players like GlaxoWellcome,
Novartis, Pfizer, Johnson &
Johnson, Abbott
• Major Indian companies
such as Wockhardt, Cipla,
Lupin, Nicholas Piramal are
making big headway in the
areas of biotechnology.
• Bio-Technology Park in Pune
and Agri-Biotech Park in
Jalna are shaping up
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Experience suggest to consider some issues (1):
Strong Science Base
Which specific fields of excellence ?
Regional brand needed : Biotechnology is a buzzword.
Entrepreneurial Culture
Growing Company Base
Ability to attract key staff
Regional attractiveness not to be neglected
Attracting staff = attracting families
Competitive wages rather than stocks
Availability of Finance
Need for public early money
Funds will eventually come where critical mass is
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Experience suggest to consider some issues (2):
Premises and Infrastructure
Adequate facilities at the right moment.
Do not expect empty buildings to attract companies
Take care of your own companies, they attract new tenants
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Bioclusters
What do we have ?
Inventory of local actors and facilitators. Think WIDE
Federate local actors before attracting external resources
What do we want ?
Sustainable Economic development
New Knowledge-based economy
Wealth from innovation
What do we need ?
Partners and friends : join networks
Political commitment, national, federal, local
Shared vision and roadmap
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US Science Park Model : Scripps Florida
… until Now ?
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Need for Bio-Clusters
Industry / Research
Entrepreneurs institutes / R&D
programs
Contract
outsourcing
Inadequate
Inadequate Reduced
Low Pvt.
Private
Capitalisation Equity capital
Equity Flow
Capitalisation
Lack
Lackof
ofstrong
strong
Promoter equity
Promoter
CAPACITY BUILDING
Directed Investments and further
facilitation through
Managerial Inputs
Liaison support (Funding agencies /
Regulatory Bodies etc)
Industry linkages and other support
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Key Constituents
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Key Constituents
Centre of Excellence
– A unit established to support and promote a particular activity and open for
collaborations.
– Could include the following:
• Demonstration Park
• Decentralised Technologies
• Central Coordination Office & Regulatory Support Cell
• Clinical Trial Coordination Offices
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Case Study – IBPL Pune
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Case Study – Haryana
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Some thoughts
Higher risk
model
Tenants
o Need to identify robust anchor companies to set up business in the Park and help in developing the eco-system
o New entrants to Indian Market (Research based firms, contract research organisations and manufacturing outfits)
o Small start-up companies and Incubation centre for nurturing ideas to inception
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Bio Services Consortium
Model 1 Model 2
MNC/New entrants,
Existing Players
Entrepreneurs
Park tenants/Other Pvt. Players/
Government run institutes
Incubation Companies
• Developmental work
IP driven research
• Sample for testing on call
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Incubation Services
Incubation Services
+
Flexibility
of accessing
Investor
- Interest
+ Infrastructure
-
Upfront Capital - Funding Probability -
Requirement Market testing
Burn Rate (BR) cost
- +
Entrepreneurs
Probability of
-
Equity partnerships success Probability of
through cheap rentals incubation centre
as trial site
+ + +
IP Creation +
Revenue Probability of
For DSC (R) India exposure
+
Incubation Services Entrepreneurs
+
CVP
+
+ +
MNC/Existing Players IP Generation
+
+
Low Upfront
Capital Requirement
+ +
+ +
+ Outsourced
Services CRADS
Shared Instrumentation Overall Client Value
Volume (OS) +
and Analytical Services + Proposition (CVP) +
+ +
Revenue
for BSC (R)
Low Cost of Services +
+
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Thank you
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