Answer the following questions with your

elbow partner:
 What physical traits did you inherit and from
whom?
 What traits can be inherited?
 Definition – diagram of family relationships that
use symbols to represent people and lines to
represent genetic relationships. (genotypes &
phenotypes)
 Example :

 Sentence – Write a sentence using the word

pedigree on your graphic organizer.
 Definition – a genotype is the genetic make
up of a cell, or the alleles
 Example – AA (homozygous dominant) Aa
(heterozygous) aa (homozygous recessive)
 Non-Example – Freckles
 Sentence
 Definition – is an organisms observable traits,
or physical characteristics.
 Example – Blue eyes, Freckles, Brown Hair
 Non-Example – Aa, AA, aa
 Sentence
 Read pages 396-397 out of your textbook.
 Answer the following questions with your
elbow partner.
◦ What are pedigree charts?
◦ What are the symbols and what do they mean?
◦ In the sample pedigree pictured on page 397, what
are the genotypes of both parents on the left in the
second generation?
◦ How do you know?
 Males & females are equally likely to have the
trait
 Traits DO NOT skip generation
 Males can transmit to both sons and
daughters
 The trait is present whenever the
corresponding gene is present
Parent 1 = Huntington’s Disease
H h
Parent 2 = Normal

h Hh (Huntington’s) hh

h Hh (Huntington’s) hh

Parent 1 = Normal
h h
Parent 2 = Normal

h hh hh

h hh hh

Parent 1 = Huntington’s Disease

H h
Parent 2 = Huntington’s Disease

H Hh (Huntington’s) Hh (Huntington’s)

h Hh (Huntington’s) Hh (Huntington’s)
 Partner 1, tell Partner 2 some of the
characteristics of an Autosomal Dominant
disorder.
 Males & females are equally likely to have the
trait
 Trait often skips generations
 Only homozygous individuals have the trait
 Parents who have children with the trait must
be heterozygous
 If a parent has the trait, their offspring who
do not have it are heterozygous carriers for
the trait
 Parent 1 = Carrier
F f
Parent 2 = Normal

F FF Ff (Carrier)

F FF Ff (Carrier)

Parent 1 = Carrier
F f
Parent 2 = Carrier

F FF Ff (Carrier)

f Ff (Carrier) ff (Cystic Fibrosis)

Parent 1 = Cystic
Fibrosis f f
Parent 2 = Carrier

F Ff (Carrier) Ff (Carrier)

f ff (Cystic Fibrosis) ff (Cystic Fibrosis)

 Partner 2, tell Partner 1 what some
characteristics of Autosomal Recessive
disorders are.
 Trait is coded for on the X chromosome
 All sons of a male who has the trait will also
have the trait
 A father can not pass the trait on to their
daughter
 A female who has the trait may or may not
pass the gene for that trait to her son or
daughter
Mom = Carrier
X0 X
Dad = Normal
X0X (CL XX
X
Syndrome)
X0Y (CL XY
Y
Syndrome)

Mom = Normal
X X
Dad = Normal

X XX XX

Y XY XY
 Partner 1, tell Partner 2 explain some of the
characteristics of an X-link Dominant
disorder.
 Trait is coded for on the X chromosome
 Trait more common in males than females
 If a male has the trait, all of his daughters will be
heterozygous carriers
 Sons of female carriers have a 50% chance of
having the trait
 Males can not pass the trait to their sons
 A male inherits the trait from his mother who is a
carrier
 Daughters of female carriers have a 50% chance
of being a carrier
Mom=Carrier
X0 X
Dad = Normal
X X0X (Carrier) XX
Y X0Y (DMD) XY

Mom = Normal
X X
Dad = Normal

X XX XX

Y XY XY
 Partner 2, tell Partner 1 some characteristics
of an X-link Recessive disorder.
 With a partner, determine whether the
pedigree is an example of a AR, AD, XR, or
XD.
 Write the answers in on your graphic
organizer.
 Does alkaptonuria
appear to be caused by a
dominant or recessive
allele?
 What are the genotypes
of the following
individuals?
◦ George
◦ Carla
◦ Tom
◦ Arlene
◦ Michael
 Work through question 18 with your elbow
partner. Be prepared to share your answers
with the class.
 Bob = Aa
 Barb = aa
 Charlie = Aa
 Ethan = aa
 Candice = Aa
 Isabelle = aa

Candice = A a
Huntington’s
50% Chance
Parker = Normal
a Aa aa
a Aa aa
 Answer the questions for question 19
individually. Be prepared to share out to the
class.
 Edward VII = XY
 Alice = XhX
 Queen Victoria = XhX
 Leopold = XhY
 Beatrice = XhX
 Henry of Prussia = XY
Leopold = Xh Y
Hemophilia 0% Chance of
Wife = Non-Carrier Hemophilia
100% Chance o
X XhX XY
being a carrier
X XhX XY
Working with a partner, read through the case
study of the Grouch family.
 Answer 20 a and 20 b with your partner.
 Hemoglobin is the iron-
containing oxygen-
transport protein in red
blood cells.
 Methemoglobin is a form
of a hemoglobin that
can’t bind oxygen. When
excess methemoglobin is
present, the blood
becomes abnormally
dark and can cause some
skin discoloration.
 Read paragraphs 1-20. Stop and write a
short summary.
 Read paragraphs 21-40. Stop and write a
short summary.
 Read paragraphs 41-58. Stop and write a
short summary.
Answer the following questions about your reading
with your partner on your graphic organizer:
 What is the name of the disorder described in the
article?
 Describe the group of people effected by this
disorder.
 Is the disorder autosomal or x-linked?
 Is the disorder recessive or dominant?
 Where did this population reside?
 Describe the symptoms of the disorder?
 How was this disorder inherited?
 Why was the disorder isolated to this population?
 Draw a pedigree chart of your family
including yourself, your parents and siblings,
your parents.
◦ Identify and color the symbols accordingly for one
of the following traits:
 Right or left handed
 Freckles
 Free/attached earlobes
 Widows peak
 Tongue roller/non-roller