Professional Documents
Culture Documents
The Respiratory
System
ANGEL LYNN R. SANTOS, MDRN
Organs of the Respiratory system
• Nose
• Pharynx
• Larynx
• Trachea
• Bronchi
• Lungs –
alveoli
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Function of the Respiratory System
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13.3a
Upper Respiratory Tract
Figure 13.2
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13.3b
Anatomy of the Nasal Cavity
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13.4a
Anatomy of the Nasal Cavity
• Lateral walls have projections called
conchae
• Increases surface area
• Increases air turbulence within the nasal
cavity
• The nasal cavity is separated from the
oral cavity by the palate
• Anterior hard palate (bone)
• Posterior soft palate (muscle)
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13.4b
Paranasal Sinuses
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13.5a
Paranasal Sinuses
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13.5b
Pharynx (Throat)
• Muscular passage from nasal cavity to
larynx
• Three regions of the pharynx
• Nasopharynx – superior region behind
nasal cavity
• Oropharynx – middle region behind mouth
• Laryngopharynx – inferior region attached
to larynx
• The oropharynx and laryngopharynx are
common passageways for air and food
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide 13.6
Structures of the Pharynx
• Thyroid cartilage
• Largest hyaline cartilage
• Protrudes anteriorly (Adam’s apple)
• Epiglottis
• Superior opening of the larynx
• Routes food to the larynx and air toward the
trachea
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13.9a
Structures of the Larynx
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13.9b
Trachea (Windpipe)
• Connects larynx with bronchi
• Lined with ciliated mucosa
• Beat continuously in the opposite direction of
incoming air
• Expel mucus loaded with dust and other
debris away from lungs
• Walls are reinforced with C-shaped
hyaline cartilage
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13.10
Primary Bronchi
Figure 13.4b
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13.12b
Coverings of the Lungs
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13.13
Respiratory Tree Divisions
• Primary bronchi
• Secondary bronchi
• Tertiary bronchi
• Bronchioli
• Terminal bronchioli
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13.14
Bronchioles
• Smallest
branches of
the bronchi
Figure 13.5a
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13.15a
Bronchioles
• Terminal
bronchioles end
in alveoli
Figure 13.5a
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13.15c
Respiratory Zone
• Structures
• Respiratory bronchioli
• Alveolar duct
• Alveoli
• Site of gas exchange
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13.16
Alveoli
• Structure of alveoli
• Alveolar duct
• Alveolar sac
• Alveolus
• Gas exchange takes place within the alveoli
in the respiratory membrane
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13.17
Respiratory Membrane
(Air-Blood Barrier)
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13.18a
Respiratory Membrane
(Air-Blood Barrier)
Figure 13.6
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13.18b
Gas Exchange
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13.20a
Events of Respiration
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13.20b
Mechanics of Breathing
(Pulmonary Ventilation)
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13.21a
Mechanics of Breathing
(Pulmonary Ventilation)
• Two phases
• Inspiration – flow of air into lung
• Expiration – air leaving lung
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13.21b
Inspiration
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13.22a
Inspiration
Figure 13.7a
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13.22b
Exhalation
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13.23a
Exhalation
Figure 13.7b
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13.23b
Accessory Muscles of
Respiration
Pressure Differences in the
Thoracic Cavity
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13.24
Nonrespiratory Air Movements
• Can be caused by reflexes or voluntary
actions
• Examples
• Cough and sneeze – clears lungs of debris
• Laughing
• Crying
• Yawn
• Hiccup
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13.25
Respiratory Volumes and Capacities
• Normal breathing moves about 500 ml of air
with each breath (tidal volume [TV])
• Many factors that affect respiratory capacity
• A person’s size
• Sex
• Age
• Physical condition
• Residual volume of air – after exhalation,
about 1200 ml of air remains in the lungs
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13.26
Respiratory Volumes and Capacities
• Residual volume
• Air remaining in lung after expiration
• About 1200 ml
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13.27b
Respiratory Volumes and Capacities
• Vital capacity
• The total amount of exchangeable air
• Vital capacity = TV + IRV + ERV
• Dead space volume
• Air that remains in conducting zone and
never reaches alveoli
• About 150 ml
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13.28
Respiratory Volumes and Capacities
• Functional volume
• Air that actually reaches the respiratory
zone
• Usually about 350 ml
• Respiratory capacities are measured
with a spirometer
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13.29
Respiratory Capacities
Figure 13.9
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13.30
The Respiratory
System
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13.31
External Respiration
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13.32a
External Respiration
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13.33a
Gas Transport in the Blood
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13.33b
Internal Respiration
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13.34a
Internal Respiration
Figure 13.11
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13.34b
External Respiration,
Gas Transport, and
Internal Respiration
Summary
Figure 13.10
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13.35
Neural Regulation of Respiration
• Activity of respiratory muscles is transmitted
to the brain by the phrenic and intercostal
nerves
• Neural centers that control rate and depth are
located in the medulla
• The pons appears to smooth out respiratory
rate
• Normal respiratory rate (eupnea) is 12–15
respirations per minute
• Hypernia is increased respiratory rate often
due to extra oxygen needs
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13.36
Neural Regulation of Respiration
Figure 13.12
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13.37
Factors Influencing Respiratory
Rate and Depth
• Physical factors
• Increased body temperature
• Exercise
• Talking
• Coughing
• Volition (conscious control)
• Emotional factors
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13.38
Factors Influencing Respiratory
Rate and Depth
• Chemical factors
• Carbon dioxide levels
• Level of carbon dioxide in the blood is the
main regulatory chemical for respiration
• Increased carbon dioxide increases
respiration
• Changes in carbon dioxide act directly on
the medulla oblongata
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13.39a
Factors Influencing Respiratory
Rate and Depth
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13.39b
Respiratory Disorders: Chronic
Obstructive Pulmonary Disease
(COPD)
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13.40a
Respiratory Disorders: Chronic
Obstructive Pulmonary Disease
(COPD)
• Features of these diseases
• Patients almost always have a history of
smoking
• Labored breathing (dyspnea) becomes
progressively more severe
• Coughing and frequent pulmonary
infections are common
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13.40b
Respiratory Disorders: Chronic
Obstructive Pulmonary Disease
(COPD)
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13.40c
Emphysema
• Alveoli enlarge as adjacent chambers break
through
• Chronic inflammation promotes lung fibrosis
• Airways collapse during expiration
• Patients use a large amount of energy to
exhale
• Overinflation of the lungs leads to a
permanently expanded barrel chest
• Cyanosis appears late in the disease
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13.41
Chronic Bronchitis
• Mucosa of the lower respiratory
passages becomes severely inflamed
• Mucus production increases
• Pooled mucus impairs ventilation and
gas exchange
• Risk of lung infection increases
• Pneumonia is common
• Hypoxia and cyanosis occur early
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13.42
Chronic Obstructive Pulmonary Disease
(COPD)
Figure 13.13
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13.43
Lung Cancer
• Accounts for 1/3 of all cancer deaths in
the United States
• Increased incidence associated with
smoking
• Three common types
• Squamous cell carcinoma
• Adenocarcinoma
• Small cell carcinoma
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13.44
Sudden Infant Death syndrome
(SIDS)
• Apparently healthy infant stops
breathing and dies during sleep
• Some cases are thought to be a
problem of the neural respiratory control
center
• One third of cases appear to be due to
heart rhythm abnormalities
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13.45
Asthma
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13.46
BRONCHIAL TUBE
Developmental Aspects of the
Respiratory System
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13.47b
Aging Effects
Myasthenia Gravis
II.LOSS OF NORMAL
Guillain-Barre’ Synd
NEGATIVE
Multiple Sclerosis PRESSURE:
Amyotropic Lateral
Sclerosis (ALS) Pneumothorax
Scleroderma Hemothorax
Pleural Effusion
Kyphoscoliosis
Empyema Thoracis
Obesity
Multiple Rib
Brain/SC Injury
Fracture (Flail
Gen. Anes./ Narcotic O. Chest)
DIFFUSIVE DISORDERS
= Disorders affecting Alveolar Diffusion
Segmental Resection—removal of
segments but not entire lobe
Wedge Resection—removal of wedges but
not entire segment; commonly done for open
lung biopsy
Non-infectious
Inflammatory
Predisposing Etiology:
@ Heredity
Precipitating Etiology:
@Extrinsic allergens
@Intrinsic allergens
Types of Asthma
A. Extrinsic or Atopic Asthma: r/t
external allergens such as:
-contactants: dust, chemicals, soaps,
perfumes, lotions, make-up
-inhalants: dust, hay, scents, smoke,
sprays
-ingestants: food, milk, chicken, beef,
pork, eggs, etc.
-Sudden changes in temperature
Types of Asthma
B. Intrinsic or Non-Atopic
Asthma= not r/t external allergens
Stress
Fatigue
Lack of Sleep
Anxiety
C. MIXED type of Asthma= both
types present
Bronchial Asthma:
Heredity + Allergens
IgE
+ Mast cells of respiratory tract =
damage to mast cells
Release
of: Histamine, Bradykinin,
Serotonin, Leukotriennes,
Prostaglandins, ECF-A, SRS-A from
damaged mast cells to respiratory
membranes
Bronchial Asthma: Pathophysiology
Inflammatory reaction @ linings of
the airway
S-welling
H-eat
A-airway obstruction
R-edness
P-ain (Back pains)
Bronchial Asthma
=S-ecretions: copious, viscous,
sticky, stringy, whitish
=S-pasms: laryngo-tracheo-
bronchial spasm
=S-welling: edema of the airway
Airway Obstruction
Dyspnea
Signs and Symptoms: Asthma
Successive episodes of coughing:
dry, hacking, non-productive cough
Increased respiratory secretions:
whitish, stringy
Wheezing on expiration
Prolonged expiration
= Improve ventilation
= Relieve signs of dyspnea
Actions:
2. EPIDERMOID CARCINOMA
Squamous Cell Type
Entirely associated with heavy smoking
History: > 1p/y
Highest incidence among Males > 40
Most common cause of death among males in US today
Centrally located in large bronchi
Incidence: 2003 Statistics……………………..30-35%
Classification: Histology
3. OAT-CELL Ca
Fusiform, polygonal
Oat-like, small cells
4. LARGE-CELL Ca
Highly metastatic
Large cells
Peripherally-located Slow-growing
Usually not operable Prognosis: Good
at time of diagnosis
Poor Prognosis
Incidence: 2003
Statistics……20-25%
METASTASES: LUNG CA
Lymph nodes
Bones
Brain
Contralateral Lung
Adrenals
Kidneys
Liver
Peritoneal organs
Diagnostic Exams: Lung Ca
Chest X-ray
Tomography
Signs and Symptoms: Lung Ca
5. CHEST PAINS/Tightness=
1. COUGH spread to regional lymph nodes
Persistent for 2-3 weeks 6. Dysphagia= spread to
Changing quality esophagus, trachea
From hacking and non- 7. Head & neck edema=spread
productive to thick and to esophagus and lymphatic
purulent sputum structures
2. HEMOPTYSIS- esp in am 8. Dyspnea
3. UNILATERAL WHEEZE on 9. Anorexia, Weight loss,
expiration (partial
obstruction) Anemia,
4. CHX IN VOICE QUALITY 10. Infections=Fever, chills
= from hoarseness to Recurring
11. Dx:
aphonia (laryngeal n. Pneumonia
compression)
PULMONARY
EMPHYSEMA
Pulmonary Emphysema
Terminal stage : C.A.L. (Chronic Airway
Limitation)
Old Name: COPD
Chief characteristics:
Precipitating Factors:
S=moking
P=ollution
A=llergies
I=nfections
Pathophysiology: Pul. Emphysema
Chronic airway obstruction
Hypercapnea
Overdilation
A. If a culture of sputum is
prescribe, transport specimen to
laboratory immediately
B. Assist the client with mouth
care
BRONCHOSCOPY
1. Direct visual examination of the larynx, trachea,
and bronchi with a fiberoptic bronchoscope
PREPROCEDURE
A. Obtain informed consent
B. NPO from midnight prior to the procedure
C. Obtain vital signs
D. Assess the results of coagulation studies
E. Remove dentures or eyeglasses
F. Prepare suction equipment
G. Administer medication for sedation as prescribed
H. Have emergency resuscitation equipment readily
available
POSTPROCEDURE
A. Monitor vitals signs
B. Maintain semi-fowler’s position
C. Assess for the return of gag reflex
D. Maintain NPO status until gag reflex returns
E. Have an emesis basin readily available for
client to expectorate sputum
F. Monitor for bloody sputum
G. Monitor respiratory status, particularly if
sedation was administered
H. Monitor for complications, such as
bronchospasm , bronchial perforation
indicated by facial or neck crepitus,
dysrhythmias, fever, bacteremia, hemorrhage,
hypoxemia, and pneumothorax
I. Notify the physician if fever, difficulty of
PULMONARY ANGIOGRAPHY
1. An invasive fluoroscopic procedure in which
a catheter is inserted through the antecubital
or femoral vein into the pulmonary artery or
one of its branches
2. Involves an injection of iodine or
radiopaque or contrast material
PREPROCEDURE
A. Obtain informed consent
B. Assess for allergies to odine, seafood, or
other radioopaque dyes
C. Maintain NPO status for 8 hours prior to the
procedure
D. Monitor vital signs
E. Assess results of coagulation studies
F. Establish an IV access
PREPROCEDURE (CONT.)
H. Instruct the client that he or she
must lie still during the procedure
I. Instuct the client that she or he may
feel an urge to cough, flushing, nausea,
or a salty taste following injection of the
dye
J. Have emergency resuscitation
equipment available
POSTPROCEDURE
A. Monitor vital signs
B. Avoid taking blood pressures for 24
hours in the extremity used for the
injection
C. Monitor peripheral neurovascular
status
THORACENTESIS
Removal of fluid or air from the pleural space
via a transthoracic aspiration
PREPROCEDURE
A. Obtain consent
B. Obtain vital signs
C. Prepare the client for ultrasound or chest
radiograph, if prescribed, prior to procedure
D. Assess results of coagulation studies
E. Note that the client is positioned sitting
upright, with the arms and head supported
by a table at the bedside during the
procedure
F. If the client cannot sit up, the client is
placed lying in bed on the unaffected side
with the head of the bed elevated 45 degrees
G. Instruct the client not to cough, breath
POSTPROCEDURE
A. Monitor vital signs
B. Monitor respiratory status
C. Apply a pressure dressing, and
assess the puncture site for
bleeding and crepitus
D. Monitor for signs of
pneumothorax, air embolism, and
pulmonary edema
PULMONARY FUNCTION TEST
- Include a number of different tests used to evaluate
lung mechanics, gas exchange, and acid base
disturbance through spirometric measurements, lung
volumes, and arterial blood gases
PREPROCEDURE
C. Determine if an analgesic that may depress the
respiratory function is being administered
D. Consult with the physician regarding holding
bronchodilators prior to testing
E. Instruct the client to void prior to procedure
and to wear loose clothing
F. Remove denture
G. Instruct the client to refrain from smoking or
eating a heavy meal for 4 to 6 hours prior to
the test
POSTPROCEDURE
LUNG BIOPSY
1. A percutaneous lung biopsy is
performed to obtain tissue for analysis
by culture or cytologic examination
2. A needle biopsy is done to identify
pulmonary lesions, changes in lung
tissue, and the cause of pleural effusion
PREPROCEDURE
A. Obtain informed consent
B. Maintain NPO status prior to the procedure
C. Inform the client that a local anesthetic
will be used but that a sensation of pressure
during needle insertion and aspiration may
be felt
POSTPROCEDURE
A. Monitor vital signs
B. Apply a dressing to the biopsy site
and monitor for drainage or bleeding
C. Monitor for signs of respiratory
distress, and notify the physician if they
occur
D. Monitor for signs of pneumothorax
and air emboli, and notify the physician
if they occur
E. Prepare the client for chest x-ray film
if prescribed
VENTILATION PERFUSION LUNG
SCAN
1. In the perfusion scan, blood flow to the lungs
is evaluated
2. The ventilation scan determines the patency
of the pulmonary airways and detects
abnormalities in ventilation
3. A radionuclide may be injected for the
procedure
PREPROCEDURE
A. Obtain informed consent
B. Assess for allergy to dye, iodine, or seafood
C. Remove jewelry around the chest area
D. Review breathing methods that may be
required during testing
POSTPROCEDURE
A. Monitor client for reaction to the
radionulide
B. For 24 hours following the procedure,
rubber gloves worn when urine is being
discarded should be washed with soap
and water before removing; then the
hands should be washed after the
gloves are removed
C. Instruct client to wash hands
carefully with soap and water for 24
hours following the procedure
SKIN TESTS
An intradermal injection used to assist in
diagnosing various infectious diseases
PREPROCEDURE
Determine hypersensitivity or previous
reactions to skin tests
PROCEDURE
A. Use a test site that is free of excessive
body hair , dermatitis, and blemishes
B. Apply at the upper one third of inner
surface of left arm
C. Circle and mark the injection test site
D. Document the date, time, and test site
POSTPROCEDURE
A. Advise the client not to scratch the
test site, to prevent infection and
abscess formation
B. Instruct the client to avoid washing
the test site
C. Interpret the reaction of the injection
site 24 to 72 hours after administration
of the test antigen
D. Assess the test site for the amount of
induration (hard swelling) in millimeters
and the presense of erythema and
vesiculation (small blister like
elevations)
ARTERIAL BLOOD GASSES
Measure the dissolved oxygen and
carbon dioxide in the arterial blood and
reveal the acid-base state and how the
oxygen is being carried to the body
NORMAL ABG VALUES
Ph: 7.35 to 7.45
Pco2: 35 to 45 mm Hg
HCO3: 22 to 27 mEq/L
Po2: 80 to 100 mm Hg
O2 saturation: 96% to 100%
Oxyhemoglobin dissociation curve: no
shift
PREPROCEDURE
A. Perform Allen’s test prior to drawing
radial artery specimens
B. Have the client rest for 30 minutes
prior to specimen collection
C. Avoid suctioning prior to drawing
ABGs
D. Do not turn off oxygen unless the
ABGs are ordered to be drawn at room
air
POSTPROCEDURE
A. Place the specimen on ice