Professional Documents
Culture Documents
- The Stomach
- The Duodenum
The Stomach
The stomach is a muscular, hollow, dilated part of the alimentary canal which functions as an important organ of the digestive tract. It is involved in the second phase of digestion, following mastication (chewing). The stomach is located between the oesophagus and the small intestine.
submucosa
Glands of Stomach
The epithelium of the stomach forms deep pits. The glands at these locations are named for the corresponding part of the stomach: Cardiac glands (at cardia) Pyloric glands (at pylorus) Fundic glands (at fundus)
GASTRIC GLAND
GASTRIC Juice
Hydrochloric acid Pepsin Intrinsic factor
1. 2. 3. 4. Mucosal cells Mucoid cells Parietal cells Chief cell
The Duodenum
The duodenum is the first section of the small intestine. The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine, where most chemical digestion takes place. In humans, the duodenum is a hollow jointed tube about 10 12 inch long connecting the stomach to the jejunum. It begins with the duodenal bulb and ends at the ligament of Treitz.
Duodenum parts
First part (superior) begins as a continuation of the duodenal end of the pylorus. Then 5cm it curves inferiorly into the superior duodenal flexure (the end of the superior part). begins at the superior duodenal flexure. At the end turn medially into the inferior duodenal flexure (the end of the descending part). begins at the inferior duodenal flexure and passes transversely to the left, crossing the right ureter. reaches the inferior border of the body of the pancreas. Then, it curves anteriorly and terminates at the duodenojejunal flexure where it joins the jejunum. The duodenojejunal flexure is surrounded by a peritoneal fold containing muscle fibres: the ligament of Treitz.
Second part
(descending)
Third part
(inferior/horizontal)
Fourth part
(ascending)
Ulcer
Definition
Destructive process of the mucous membranes and underlying layers, common in the stomach and duodenum, caused by the damaging action of chloride-peptic secretion
Other locations: distal esophagus, post-anastomotic jejunal loop, Meckel's diverticulum
Positions of Ulcers
STOMACH: on top of small curvature, in intermediate portion between the body and pyloric antrum DUODENUM: commonly in the bulb, immediate near the pylorus
almost every time, an acute gastric mucosal lesions is caused by the use or abuse of anti-inflammatory drugs, including aspirin, that is acetylsalicylic acid or other (indomethacin, ibuprofen, naproxen, tolmetin, sulindac, piroxicam, fenoprofen). In these cases in the patient, since the drug is absorbed through backscattering in the gastric mucosa, there are superficial antral erosions with bleeding.
Gastric Ulcers
very important is the differential diagnosis with stomach cancer the ulcer was confirmed by endoscopic examination and radiological the first symptom is commonly represented by epigastric pain. antacids provide prompt relief, while food, after a temporary wellness, can induce growth.
Duodenal Ulcer
The pain typically appears from 1 to 3 hours after a meal (late) An ingestion of food results in a resolution of pain in a short time A typical seasonal increase in spring and autumn
Clinical Differences
STOMACH: -older age - decreased motility - reduced secretion at rest -DUODENUM: - more sensitive to the resting basal stimulus - regress with food
Complications of Ulcers
Hemorrhage Perforation (the most common site duodenum) Pyloric stenosis Malignant degeneration (1-5% of gastric cases caused by Helicobacter Pylori)
Malignant ulcer: endoscopic view of cancer
Therapy
Before talking about the diet in case of ulcer, shown the severity of the disease, is right to say a word about medical treatments, which are much more timely and useful MEDICAL THERAPY In about of patients with ulcer, medical treatment (antacids, histamine H2 receptor antagonists, proton pump inhibitors, somatostatin) is sufficient to stop the bleeding and stabilize the condition. The placement of a nasogastric tube of large caliber allows flushing of the stomach, the aspiration of blood clots, and monitoring any resumption of bleeding. The electrocoagulation, a lasercoagulation, tissue adhesives, fibrin glue, collagen can be useful sometimes decisive. In patients infected by Helicobacter pylori will be associated an antibiotic therapy.
Surgical Therapy
25% of patients with an acute ulcer still requires the use of emergency surgery. The surgery is aimed first of all to identify and arrest (by suturing / or ligation) the source of hemorrhage. After, it's possible to proceed to one of the surgical treatment valid for ulcer: Vagotomy simple Vagotomy + antrectomy (with Reset of gastrointestinal continuity).
The diet in case of ulcer is a diet low in vitamins B1, C, calcium and iron. It can be used in case of gastric and duodenal ulcer, bleeding or healing phase). In general, the diet for an ulcer is governed by the following points: eat at regular intervals, variety of foods, exclude irritant and stimulants foods for of the secretions of the stomach. Other suggestions: Eat slowly, chewing carefully Have a snack between main meals and before bedtime Avoid heavy meals (with the ulcer is better to eat little but often) Avoid tea, coffee, alcohol, fried foods, fatty cheeses, fatty meats, spices
A new Discovery!
A recent study, published on the world-magazine of gastroenterology, discovered the protective effects of arugula about gastric and duodenal ulcer in an animal model (mouse). Although the prickly taste, the arugula protected the mice's stomach from damage, induced by alcohol and indomethacin. The results are very good, and certainly should be detailed on man before take conclusions.